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The antioxidant potential of bacoside and its derivatives in Alzheimer's disease: The molecular mechanistic paths and therapeutic prospects
Published 2025-06-01Subjects: Get full text
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3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors
Published 2025-01-01Subjects: “…neuroprotective activity…”
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144
4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
Published 2023-07-01Subjects: Get full text
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145
Pharmacological inhibition of carbonic anhydrases with a positively charged pyridinium sulfonamide phenocopies the neuroprotective effects of Car9 genetic ablation in a murine setting of oxygen/glucose deprivation followed by re-oxygenation and is associated with improved neuronal function in ischemic rats
Published 2025-02-01“…The treatments exerted neuroprotective effects on neurons from Car9 knockout mice. …”
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146
Multivalent Neuroprotective Activity of <i>Elettaria cardamomum</i> (Cardamom) and <i>Foeniculum vulgare</i> (Fennel) in H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress in SH-SY5Y Cells and Acellular Assays
Published 2024-12-01“…This study was performed to evaluate their neuroprotective ability based on certain acellular and cellular assays. …”
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147
The intricate interplay between dietary habits and cognitive function: insights from the gut-brain axis
Published 2025-01-01Subjects: Get full text
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148
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The potential therapeutic effects of coenzyme Q10 on the sciatic nerve regeneration following short- and long-term injury
Published 2025-01-01“…Exploration of Neuroprotective Therapy…”
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150
The E3-ligase Siah2 activates mitochondrial quality control in neurons to maintain energy metabolism during ischemic brain tolerance
Published 2025-01-01“…Therefore, in the present study, we investigated the role of Siah2 in the IPC-induced neuroprotection in in vitro and in vivo models of IPC. …”
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151
Amelioration of Behavioural, Biochemical, and Neurophysiological Deficits by Combination of Monosodium Glutamate with Resveratrol/Alpha-Lipoic Acid/Coenzyme Q10 in Rat Model of Cis...
Published 2013-01-01“…The results suggested that pretreatment with the combination of MSG (500 mg/kg/day po) with resveratrol (10 mg/kg/day i.p.) or ALA (20 mg/kg/day i.p.) or CoQ10 (10 mg/kg weekly thrice i.p.) exhibited neuroprotective effect. The maximum neuroprotection of MSG was observed in the combination with resveratrol.…”
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152
Long-Standing Motor and Sensory Recovery following Acute Fibrin Sealant Based Neonatal Sciatic Nerve Repair
Published 2016-01-01“…Therefore, this study evaluated neuroprotection and regeneration after neonatal peripheral nerve coaptation with fibrin sealant. …”
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153
Bioprospecting of Microbes for Valuable Compounds to Mankind
Published 2020-06-01“…Hence, soils become an intensively utilized ecological niche for the inhabitants to generate various useful biologically active natural products such as antibiotics, antifungal, antiviral, antioxidant, neuroprotection, anticancer and other important compounds. …”
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154
Effects of Electroacupuncture at Governor Vessel Acupoints on Neurotrophin-3 in Rats with Experimental Spinal Cord Injury
Published 2016-01-01“…We investigated the response of EA at Dazhui (GV 14) and Mingmen (GV 4) acupoints to understand the effects and mechanisms of EA in neuroprotection and neuronal function recovery after SCI. …”
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Correlation between the Neutrophil-to-Lymphocyte Ratio and Multiple Sclerosis: Recent Understanding and Potential Application Perspectives
Published 2022-01-01“…The underlying pathophysiology is highlighted to identify new potential targets for neuroprotection and to develop novel therapeutic strategies.…”
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156
A Review of Nonanesthetic Uses of Ketamine
Published 2020-01-01“…MEDLINE, CINAHL, and Google Scholar databases were queried to find articles related to ketamine in the treatment of depression, pain syndromes including acute pain, chronic pain, and headache, neurologic applications including neuroprotection and seizures, and alcohol and substance use disorders. …”
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157
Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX...
Published 2024-01-01“…The present study aimed to explore the neuroprotective effects of total flavonoids extracted from A. membranaceus (TFA) and their protective mechanisms. …”
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158
Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions
Published 2018-01-01“…This review will discuss the role of TDP-43 and FUS in RNA metabolism, with an emphasis on the involvement of this process in synaptic function and neuroprotection. This will be followed by a discussion of the potential phase separation mechanism for forming RNP granules and pathological inclusions.…”
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Impact of Aging in Microglia-Mediated D-Serine Balance in the CNS
Published 2018-01-01“…A mild chronic inflammatory state, like that observed in aged individuals, affects microglial function, inducing a dysfunctional phenotype that potentiates neuroinflammation and cytotoxicity instead of neuroprotection in response to additional challenges. …”
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160
Day and Night GSH and MDA Levels in Healthy Adults and Effects of Different Doses of Melatonin on These Parameters
Published 2011-01-01“…The pineal secretory product melatonin (chemically, N-acetyl-5-methoxytryptamine) acts as an effective antioxidant and free-radical scavenger and plays an important role in several physiological functions such as sleep induction, immunomodulation, cardiovascular protection, thermoregulation, neuroprotection, tumor-suppression and oncostasis. Membrane lipid-peroxidation in terms of malondialdehyde (MDA) and intracellular glutathione (GSH) is considered to be a reliable marker of oxidative stress. …”
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