Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism by L. Di Cesare Mannelli, G. D'Agostino, A. Pacini, R. Russo, M. Zanardelli, C. Ghelardini, A. Calignano

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Neuroprotective Effect of Leaf Extract of Moringa Oleifera And Fenofibrate on Learning and Memory in Wistar Rats Subjected to Water Immersion Restraint Stress by Stephen, Olawale Ajayi, Iliya, Ezekiel, Iliya, Andesire, Agnes, Igimi Odey, Ajayi, Damilola Ife, Ejike, Daniel Eze

Subjects: “…Neuroprotective…”
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Neuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson’s Disease: Involvement of the PI3K/Akt/GSK3β Pathway by Wei Zhang, Hong He, Hujie Song, Junjie Zhao, Tao Li, Leitao Wu, Xiaojun Zhang, Jianzong Chen

“…These results show that Sal prevents the loss of dopaminergic neurons and the PI3K/Akt/GSK3β pathway signaling pathway may have mediated the protection of Sal against MPTP, suggesting that Sal may be a potential candidate in neuroprotective treatment for PD.…”
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Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer’s disease: an overview of pre-clinical studies focused on β-amyloid peptide by Kumju Youn, Chi-Tang Ho, Mira Jun

“…This review demonstrated multiple neuroprotective efficacies of EGCG by focusing on the involvement of Aβ-evoked damage and its Aβ regulation. …”
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Neuroprotective effects of gastrodin in both in vivo and in vitro models of Parkinson's disease: Mechanisms from the perspective of oxidative stress, ferroptosis, and cellular senescence by Shanshan Li, Meng Wang, Buyun Jia, Baikun Li, Hui Cheng, Shasha Tian, Qinglin Li

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GENI as an AMPK Activator Binds α and γ Subunits and Improves the Memory Dysfunction of Alzheimer’s Disease Mouse Models via Autophagy and Neuroprotection by Ying Wang, Lanjie Li, Danni Chen, Jiaheng Shan, Meijuan Yi, Hiroyuki Osada, Minoru Yoshida, Lan Xiang, Jianhua Qi

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Neuroprotective and Antiapoptotic Activity of Lineage-Negative Bone Marrow Cells after Intravitreal Injection in a Mouse Model of Acute Retinal Injury by Anna Machalińska, Dorota Rogińska, Ewa Pius-Sadowska, Miłosz P. Kawa, Edyta Paczkowska, Michał Rudnicki, Renata Lejkowska, Bartłomiej Baumert, Barbara Wiszniewska, Bogusław Machaliński

“…Collectively, our data demonstrate that transplanted Lin−BMCs exert neuroprotective function against acute retinal injury and this effect may be associated with their antiapoptotic properties and ability to express neurotrophic factors.…”
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Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson’s Disease by Kelly Rose Tavares Neves, Hélio Vitoriano Nobre, Luzia Kalyne A. M. Leal, Geanne Matos de Andrade, Gerly Anne de Castro Brito, Glauce Socorro de Barros Viana

“…In conclusion, we demonstrated a neuroprotective effect of PTX, possibly related to its anti-inflammatory and antioxidant actions, indicating its potential as an adjunct treatment for PD.…”
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N-Acetylcysteine in Combination with IGF-1 Enhances Neuroprotection against Proteasome Dysfunction-Induced Neurotoxicity in SH-SY5Y Cells by Benxu Cheng, Pinki Anand, Anxiu Kuang, Feroz Akhtar, Virginia L. Scofield

“…Previous studies focused on individual neuroprotective agents and their respective abilities to prevent neurotoxicity following a variety of toxic insults. …”
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Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy by Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji, Bin Liu

“…The present study aimed to explore the neuroprotective role of cortistatin-14 in sepsis-associated encephalopathy and its underlying mechanisms in a mouse model. …”
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Retinal Protection of New Nutraceutical Formulation by Luca Rosario La Rosa, Veronica Pepe, Francesca Lazzara, Giovanni Luca Romano, Federica Conti, Erika Giuffrida, Claudio Bucolo, Santa Viola, Giuseppe De Pasquale, Maria Cristina Curatolo, Cristina Zappulla

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Maximizing the neuroprotection from Citrus aurantium leaves: Optimization of a blended extract from a sequential extraction process with compressed fluids and NADES by Victor M. Amador-Luna, Miguel Herrero, Marta Jiménez de la Parra, Ángel Gómez Arribas, Elena Ibáñez, Lidia Montero

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Neuroprotective Effect of Taurine against Cell Death, Glial Changes, and Neuronal Loss in the Cerebellum of Rats Exposed to Chronic-Recurrent Neuroinflammation Induced by LPS by Samara P. Silva, Adriana M. Zago, Fabiano B. Carvalho, Lucas Germann, Gabriela de M. Colombo, Francine L. Rahmeier, Jessié M. Gutierres, Cristina R. Reschke, Margarete D. Bagatini, Charles E. Assmann, Marilda da C. Fernandes

“…The present study investigated the neuroprotective effect of taurine against the deleterious effects of chronic-recurrent neuroinflammation induced by LPS in the cerebellum of rats. …”
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NMDA Receptor-Mediated Neuroprotective Effect of the Scutellaria baicalensis Georgi Extract on the Excitotoxic Neuronal Cell Death in Primary Rat Cortical Cell Cultures by Jinsong Yang, Xiaohong Wu, Haogang Yu, Xinbiao Liao, Lisong Teng

“…Thus, S.B. extract exhibited neuroprotection against excitotoxic cell death, and this neuroprotection was mediated through the inhibition of NMDA receptor function by interacting with the glycine binding site of the NMDA receptor. …”
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Inhibition of the Transforming Growth Factor-β Signaling Pathway Confers Neuroprotective Effects on Beta-Amyloid-Induced Direct Neurotoxicity and Microglia-Mediated Neuroinflammation by Shao Qin Tiong, Raxshanaa N. Mohgan, Jia Yee Quek, Jennifer Yue Suan Liew, Grace Yee Seen Wong, Zi Qing Thang, Zhi Ling Chan, Sook Yee Gan, Elaine Wan Ling Chan

“…Conclusion: The inhibition of the TGF-β signaling pathway in neuronal and microglia cells by TGF-βR1 inhibitors resulted in neuroprotection against Aβ-induced direct neurotoxicity and microglia-mediated neuroinflammation. …”
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MFG-E8 Exerts Neuroprotection in Neural Stem Cells Induced by Anesthetic Sevoflurane via Regulating the PI3K/AKT Pathways by Minmin Cai, Liufang Sheng

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Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury by Wen-zhao Liu, Zhan-jun Ma, Ji-he Kang, Ai-xin Lin, Zhao-heng Wang, Hai-wei Chen, Xu-dong Guo, Xue-gang He, Xue-wen Kang

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Exploring phytochemicals and their pharmacological applications from ethnomedicinal plants: A focus on Lycium barbarum, Solanacea by Baiken Baimakhanova, Amankeldi Sadanov, Andrey Bogoyavlenskiy, Vladimir Berezin, Lyudmila Trenozhnikova, Gul Baimakhanova, Aibat Ibraimov, Elmira Serikbayeva, Zhalgaskali Arystanov, Tanagul Arystanova, Rakhym Nazakat, Ainura Khammetova, Gulnaz Seitimova, Aknur Turgumbayeva

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Protective effects of wogonin in the treatment of central nervous system and degenerative diseases by Qingan Fu, Qingyun Yu, Hongdan Luo, Zhekang Liu, Xiaowei Ma, Huijian Wang, Zhijuan Cheng

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Citrulline – The Powerhouse Nutrient for Cardiometabolic and Brain Health by Daria Pedrycz, Mateusz Drabczyk, Emilia Pedrycz, Karolina Karoń, Grzegorz Drapała, Wojciech Grabowski, Łukasz Karoń, Anna Zygmunt, Sławomir Karoń

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