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5021
CLINICAL CHARACTERISTICS OF DEBUT AND RISK FACTORS OF PEDIATRIC MULTIPLE SCLEROSIS
Published 2024-11-01“…The study was conducted on the basis of the neurological departments of the State Children's Clinical Hospital N 3 and the Collective Children's Clinical Hospital in Omsk. …”
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5022
Association between edaravone use and activities of daily living in older patients with atherothrombotic stroke: an observational study using Japanese real-world data
Published 2025-01-01“…Abstract Background Edaravone is marketed in nine countries, although only Japan has approved edaravone for improvement of neurological symptom, disability of activities of daily living (ADL), and functional disability associated with acute stroke. …”
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5023
Skeletal abnormalities caused by a Connexin43R239Q mutation in a mouse model for autosomal recessive craniometaphyseal dysplasia
Published 2025-01-01“…Many patients with CMD suffer from neurological symptoms. The pathogenesis of CMD is not fully understood. …”
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5024
Stroke Event Factors among Adult Patients Admitted to Stroke Unit of Jimma University Medical Center: Prospective Observational Study
Published 2019-01-01“…Majority of patients (40.5%) showed severe neurological deficit on admission and the mean National Institute of health stroke scale (NIHSS) was 15.71 ± 7.52. …”
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5025
Pleomorphic xanthoastrocytoma, case series and review of literature
Published 2025-02-01“…All cases presented with seizures, only one case showed neurological deficit. The solid portions showed hyperintense signal in diffusion-weighted image in three cases (Pleomorphic xanthoastrocytoma grade 3), while two cases showed isointense signal (Pleomorphic xanthoastrocytoma grade 2). …”
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5026
Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neu...
Published 2023-01-01“…Mesenchymal stem cells have been shown to be potential therapeutic agents for neurological disorders. In the current study, we aimed to examine the effects of Wharton’s jelly-derived mesenchymal stem cell-conditioned medium (WJMSC-CM) on learning and memory, oxidative stress, apoptosis, and histological changes in the hippocampus of diabetic rats. …”
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5027
Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro.
Published 2025-01-01“…Epilepsy is a prevalent neurological disorder that affects approximately 1% of the global population. …”
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5028
Navigating large-volume subcutaneous injections of biopharmaceuticals: a systematic review of clinical pipelines and approved products
Published 2024-12-01“…These LVSCs are designed to target cancer and a range of non-cancer chronic disease states, including autoimmune, neurological, and cardiovascular diseases. Results show that anti-cancer LVSCs (n = 75) typically require 5.0 to 20.0 mL doses every three weeks and are administered by healthcare professionals. …”
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5029
Risk factors for re-hospitalization within 90 days of discharge for severe influenza in children
Published 2025-01-01“…M. pneumoniae and influenza virus are the most common infections for readmission The children who were readmitted were more likely to have critical influenza and neurological comorbidities compared to patients without readmission. …”
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5030
Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail
Published 2019-01-01“…Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders. MSCs can be obtained from many different sources, and the present study compares the potential of neuronal transdifferentiation in MSCs from adult and neonatal sources (Wharton’s jelly (WhJ), dental pulp (DP), periodontal ligament (PDL), gingival tissue (GT), dermis (SK), placenta (PLAC), and umbilical cord blood (UCB)) with a protocol previously tested in bone marrow- (BM-) MSCs consisting of a cocktail of six small molecules: I-BET151, CHIR99021, forskolin, RepSox, Y-27632, and dbcAMP (ICFRYA). …”
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5031
Non-Redox-Based Electrochemical Detection of Adrenaline: A Simple and Reliable Approach Using Glass Nanopipets
Published 2025-01-01“…The detection of adrenaline (Adr) is essential for monitoring physiological and clinical conditions, including stress response, cardiovascular health, and neurological disorders. We present a novel glass-nanopipet electrode sensor based on a non-redox ion-transfer approach using ion transfer across two immiscible electrolyte solutions (ITIES). …”
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5032
Six Novel ATM Gene Variants in Sri Lankan Patients with Ataxia Telangiectasia
Published 2020-01-01“…It is characterized by progressive ataxia beginning from early childhood. The neurological deficit associated with this condition affects one’s balance, coordination, walking, and speech and can be accompanied by chorea, myoclonus, and neuropathy. …”
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5033
Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients
Published 2025-02-01“…Our findings offer a new insight into the neural mechanism of ALS, underscoring the importance of personalized diagnostic approaches for this complex neurological disorder.…”
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5034
Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022–2023
Published 2025-03-01“…Ducks inoculated with genotypes 22G1 or 22G7 (A/duck/Korea/H537/2022(H5N1)) showed neurological signs, with 60 %–80 % mortality rate. In the contact groups of ducks, 100 % of transmissibility was observed. …”
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5035
Evaluating the mental and emotional effects of Sahand Bonab thermal power plant greenhouse on rural communities, Case study: Rurlas in Bonab
Published 2019-06-01“…Also, analysis of the results by using a Pearson test showed that six variables including neurological and disturbing variables p= 0.272, stress and psychological stress p= 0.325, feeling of energy decrease, p= 0.287, feeling of despair and disappointment in life p = 0.142, feeling Depression in life of p= 0.211 and change in behavior patterns in everyday life p= 0.269 had the most effect on air pollution. …”
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5036
Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice
Published 2021-01-01“…In addition, effective pharmacotherapy for PDP may also facilitate the use of other medications needed to treat neurological symptoms of PD (e.g., tremor, bradykinesia, and dyskinesia), although they may also have adverse effects that contribute to symptoms of PDP.…”
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5037
Disposition to pediatric intensive care unit post supraglottoplasty repair: a systematic review
Published 2023-04-01“…The included studies revealed several patient and surgical factors have been linked to postoperative respiratory issues requiring PICU admission, including: neurological disease, perioperative oxygen saturation < 95%, prolonged surgical time and age < 2 months. …”
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5038
Monoclonal Gammopathy of Undetermined Significance with Amyloid Deposition in the Lung and Non-Amyloid Eosinophilic Deposition in the Brain: A Case Report
Published 2010-01-01“…There was no focal deficit on neurological exam. Past medical history (PMH) included hypertension, hypercholesterolemia, aortic valve replacement (nonmetallic), incomplete heart block controlled by a pacemaker and IgG- IgA type Monoclonal Gammopathy of Undetermined Significance. …”
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5039
Identification of a pathogenic founder variant in the WFS1 gene that causes Wolfram syndrome in the Druze population
Published 2025-01-01“…Three had hearing loss and neurological involvement, and none had diabetes insipidus. …”
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5040
Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents
Published 2024-01-01“…Their deregulation is associated with neurological dysfunction and leukaemia. Variation in allele frequencies showed differences between continents, with rs757110 and rs2066827 having higher expression than rs12140153 and rs140386498. …”
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