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4721
Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice
Published 2025-01-01“…Traumatic brain injury (TBI) is one of the major causes of severe neurological disorders and long-term dysfunction in the nervous system. …”
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4722
Characterization of patients operated on for non-syndromic craniosynostosis. Villa Clara, 2018-2022
Published 2023-03-01“…The most frequent form of presentation is scaphocephaly and it can be associated with neurological symptoms and signs. Surgical techniques performed for remodeling of the cranial vault must be performed before the first year of life, in order to reduce the complications rate.…”
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4723
Conformational diversity in class C GPCR positive allosteric modulation
Published 2025-01-01“…The mGlu receptors signal transduction can be allosterically potentiated by positive allosteric modulators (PAMs) binding to the 7TMs, which are of therapeutic interest in various neurological disorders. Here, we report the cryoEM structures of metabotropic glutamate receptor 5 (mGlu5) purified with three chemically and pharmacologically distinct PAMs. …”
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4724
Mortality Due to Subarachnoid Hemorrhage from 1999 to 2003.
Published 2007-08-01“…Two thirds of the deaths were neurological where cerebral edema with endocrania hypertension and herniation followed by bronchopneumonia were predominant. …”
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4725
Th17 Cell Response in SOD1G93A Mice following Motor Nerve Injury
Published 2016-01-01“…In conclusion, SOD1G93A mice exhibit abnormal CD4+ T cell activation with increased levels of Th17 cells prior to the onset of neurological symptoms. Motor nerve injury exacerbates Th17 cell responses and may contribute to the development of ALS, especially in those who carry genetic susceptibility to this disease.…”
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4726
Phenotyping the males of mouse and rat strains with genetically defined behavioral disturbances in a model of sexual activation
Published 2015-12-01“…Sexual dysfunctions are caused by aging, stress, or side effects of psychotropic drugs; they are symptoms of a variety of neurological and psychiatric disorders. Therefore, the study of sexual behavior appears to be an important step in modeling various animal pathologies and the effects of psychotropic drugs. …”
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4727
Expansion of Natural Killer Cells in Peripheral Blood in a Japanese Elderly with Human T-Cell Lymphotropic Virus Type 1-Related Skin Lesions
Published 2014-01-01“…Natural killer (NK) cells were proposed to play an important role in the pathogenesis of human T-cell lymphotropic virus type 1- (HTLV-1-) associated neurologic disease. Our patient was a 77-year-old Japanese man, who had been treated for infective dermatitis associated with HTLV-1 for nearly 10 years. …”
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4728
deutetrabenazine for the treatment of chorea associated with Huntington’s disease
Published 2022-06-01“…Chorea is a movement disorder present in multiple neurologic diseases that causes involuntary and irregular muscle movements theorized to be stemming from high dopamine levels. …”
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4729
Bifurcation Analysis and Synchronous Patterns between Field Coupled Neurons with Time Delay
Published 2022-01-01“…Exploring the biophysical properties of coupling channels is of great significance for further understanding the rhythm transitions of neural network electrical activity patterns and preventing neurological diseases. From the perspective of biophysics, the activation of magnetic field coupling is the result of the continuous release and propagation of intracellular and extracellular ions, which is very similar to the activation of chemical synaptic coupling through the continuous release of neurotransmitters. …”
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4730
Drug response is related to NR3C1 and FAAH polymorphism in Chinese pediatric epilepsy patients
Published 2025-02-01“…Abstract Background Childhood epilepsy is a common neurological syndrome with complex etiology and recurrent seizures. …”
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4731
The Prevalence of Restless Legs Syndrome in Patients with Migraine: A Systematic Review and Meta-Analysis
Published 2020-01-01“…Migraine is a severe and debilitating neurologic disorder and is claimed to be the sixth disabling illness in the world. …”
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4732
Neurosurgical aspects of marble bone disease: treatment modalities and outcome
Published 2025-02-01“…Conclusion Marble bone disease or osteopetrosis is a rare hereditary disorder with multiple neurological impacts. Increased ICP and CNs compression are the most common. …”
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4733
Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease
Published 2025-01-01“…Enterovirus-D68 (EV68) continues to present as a global health issue causing respiratory illness and outbreaks associated with long-lasting neurological disease, with no antivirals or specific treatment options. …”
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4734
Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease
Published 2024-11-01“…Our data suggest that PDE12 regulates mitochondrial RNA processing and its loss results in neurological and muscular phenotypes.…”
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4735
Prion Diseases and the Gastrointestinal Tract
Published 2006-01-01“…They are uniformly fatal neurological diseases, which are characterized by ataxia and vacuolation in the central nervous system. …”
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4736
Altered Brain Glucose Consumption in Cogan’s Syndrome
Published 2016-01-01“…This study revealed areas of significantly altered CMRglc in patients with CS (any subform) without neurologic complains and normal conventional neuroimaging. …”
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4737
Myasthenic Crisis in an Elderly Patient with Positive Antibodies against Acetylcholine and Anti-MuSK, Successfully Treated with Noninvasive Mechanical Ventilation
Published 2015-01-01“…After 24 hours the patient showed respiratory deterioration and neurological impairment. Endotracheal intubation was rejected, so ventilatory support with noninvasive ventilation was started. …”
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4738
Dose and strain dependent lethality of Usutu virus in an Ifnar−/− mouse model
Published 2025-01-01“…While usually mild or asymptomatic in humans, neurological disorders are increasingly observed, which has boosted interest and the need for better understanding of the pathogenesis of various USUV lineages. …”
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4739
Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury
Published 2025-03-01“…Our findings demonstrate that EJCDs effectively reduce myeloid cell infiltration post-spinal cord injury and promote neurological recovery, making them promising therapeutic candidates for treating spinal cord injuries.…”
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4740
Basic Medical Emergency Treatment for Maxillofacial Injuries
Published 2025-01-01“…These modifications often incorporate DRSABCDE, a comprehensive evaluation that includes airway clearance with C-spine control, breathing, ventilation, oxygenation, circulation, disability-neurologic status, exposure-environment, and body temperature. …”
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