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COMPARISON OF COGNITIVE FUNCTION AND DEPRESSIVE SYMPTOMS IN INSTITUTIONALIZED HEALTHY AND OLDER PERSON WITH ALZHEIMER’S DISEASE
Published 2024-09-01“…So, the purpose of this study was to compare cognitive function and depressive symptoms in two groups: a group of older adults with Alzheimer’s disease and a group of older adults without neurodegenerative diseases, by sex and level of physical activity. …”
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222
4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
Published 2023-07-01“…Many approaches to neurodegenerative diseases that focus on amyloid-β clearance and gene therapy have not been successful. …”
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223
Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
Published 2010-01-01“…While TLR signaling was linked to neurogenesis, it was also found to be involved in the pathogenesis of neurodegenerative diseases. This paper will focus on TLR signaling in glial cells in neurodegenerative diseases such as Alzheimer's disease, prion diseases, amyotrophic lateral sclerosis, and Parkinson's disease. …”
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224
The Emerging Role of Proteolysis in Mitochondrial Quality Control and the Etiology of Parkinson’s Disease
Published 2012-01-01“…Mitochondrial biology and dysfunction have recently been linked to different types of cancers and neurodegenerative diseases, most notably Parkinson’s disease. …”
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225
Dynamics of retinal changes in early-stage Parkinson’s disease
Published 2025-01-01Get full text
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226
MitoSeg: Mitochondria segmentation tool
Published 2025-05-01“…Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and cristae structures of mitochondria in detail. …”
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227
Strategies for Regenerating Striatal Neurons in the Adult Brain by Using Endogenous Neural Stem Cells
Published 2011-01-01“…Currently, there is no effective treatment for the marked neuronal loss caused by neurodegenerative diseases, such as Huntington's disease (HD) or ischemic stroke. …”
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228
The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases
Published 2016-01-01“…The ongoing epidemics of metabolic diseases and increase in the older population have increased the incidences of neurodegenerative diseases. Evidence from murine and cell line models has implicated calcineurin-nuclear factor of activated T-lymphocytes (NFAT) signaling pathway, a Ca2+/calmodulin-dependent major proinflammatory pathway, in the pathogenesis of these diseases. …”
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229
Change of Accent as an Atypical Onset of non Fluent Primary Progressive Aphasia
Published 2013-01-01“…Language disorders can be the first symptom of many neurodegenerative diseases, including Alzheimer's disease (AD) and primary progressive aphasia (PPA). …”
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230
Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease
Published 2025-01-01“…Currently, available treatments for various neurodegenerative diseases can alleviate symptoms but do not provide a definitive cure. …”
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231
Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence
Published 2024-12-01“…The article aims to highlight the potential role of HERVs in neurodegenerative diseases such as Alzheimer’s disease and senescence. …”
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232
Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease
Published 2018-01-01“…Neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) impose a pressing burden on our developed and consequently aging society. …”
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233
Genetic Insights Into the Role of Cathepsins in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis: Evidence From Mendelian Randomization Study
Published 2025-01-01“…Abstract Background Previous studies have confirmed the significant role of cathepsins in the development of neurodegenerative diseases. We aimed to determine whether genetically predicted 10 cathepsins may have a causal effect on Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). …”
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234
Sleep Quality and Levodopa Intestinal Gel Infusion in Parkinson’s Disease: A Pilot Study
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235
Emerging role of gut microbiota extracellular vesicle in neurodegenerative disorders and insights on their therapeutic management
Published 2024-12-01“…Vesicle components contact immune receptors, initiating neuroinflammatory immune responses and causing neurodegenerative diseases. This study seeks to explain how the gut microbiota and its extracellular vesicles cause or worsen neurodegenerative diseases. …”
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Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reacti...
Published 2012-01-01“…Reduced activity of brain α-ketoglutarate dehydrogenase complex (KGDHC) occurs in a number of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. …”
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238
Microglia and Synapse: Interactions in Health and Neurodegeneration
Published 2013-01-01“…However, in neurodegenerative diseases that are associated with misfolding and aggregation of synaptic proteins, these vital defensive functions appear to be compromised. …”
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239
Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease
Published 2015-01-01Get full text
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240
Biomechanics Parameters of Gait Analysis to Characterize Parkinson’s Disease: A Scoping Review
Published 2025-01-01Get full text
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