Sicca Symptoms in Parkinson’s Disease: Association with Other Nonmotor Symptoms and Health-Related Quality of Life by Tino Prell, Denise Schaller, Caroline Perner, Otto W. Witte, Julian Grosskreutz

“…Autonomic symptoms (Survey of Autonomic Symptoms, SASs), motor function (Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale III, MDS-UPDRS III), nonmotor symptoms (nonmotor symptoms questionnaire, NMS-Quest), and QoL (PD Questionnaire-39, PDQ-39) were analysed in 93 PD patients without dementia. …”
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Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways by Zeynab Pirmoradi, Zahra Esmaili, Mohsen Nakhaie, Kristi A. Kohlmeier, Mohammad Shabani, Moazamehosadat Razavinasab, Mehran Ilaghi

“…ABSTRACT Purpose Essential tremor (ET) is a prevalent movement disorder, yet current therapeutic options remain limited. …”
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Multiple Comorbidities, Psychiatric Disorders, Healthcare Resource Utilization and Costs Among Adults with Essential Tremor: A Retrospective Observational Study in a Large US Comme... by Dingwei Dai, Ali Samiian, Joaquim Fernandes, Henriette Coetzer

“…**Background:** Essential tremor (ET), the most common movement disorder, often impairs patients’ ability to perform activities of daily living, mental health, and quality of life. …”
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Addenbrooke’s Cognitive Examination and Individual Domain Cut-Off Scores for Discriminating between Different Cognitive Subtypes of Parkinson’s Disease by Dagmar Berankova, Eva Janousova, Martina Mrackova, Ilona Eliasova, Milena Kostalova, Svetlana Skutilova, Irena Rektorova

“…We examined three age-matched groups of PD patients diagnosed according to the Movement Disorder Society Task Force criteria: PD-NC, PD-MCI, and PD-D. …”
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Trait Impulsivity Is Independent of Mild Cognitive Impairment in a Parkinson’s Disease Cohort by Ashani Jeyadevan, Megan C. Bakeberg, Michelle Byrnes, Jade Kenna, Soumya Ghosh, Rick Stell, Sue Walters, Tess Evans, Sarah McGregor, Malcolm Horne, Frank L. Mastaglia, Ryan S. Anderton

“…A total of 302 patients with idiopathic PD were recruited sequentially from three Australian Movement Disorder clinics. Based on cognitive scores, participants were divided into two groups, one defined as having mild cognitive impairment (PD-MCI; n = 113) and the other with normal cognitive function (PD-C; n = 189). …”
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Cross-Cultural Validity, Reliability, and Psychometric Properties of the Persian Version of the Scales for Outcomes in Parkinson’s Disease-Psychosocial Questionnaire by Seyed-Mohammad Fereshtehnejad, Farzaneh Farhadi, Hasti Hadizadeh, Gholam Ali Shahidi, Ahmad Delbari, Johan Lökk

“…One hundred and ten nondemented idiopathic Parkinson’s disease (IPD) patients were consecutively recruited from an outpatient referral movement disorder clinic. Eligible patients filled up a number of questionnaires including the Persian version of SCOPA-PS during the face-to-face interview session and clinical examination to measure disease severity, nonmotor psychiatric symptoms, and health-related quality of life (HRQoL). …”
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A Rare Case of Mosaic 3pter and 5pter Deletion-Duplication with Autism Spectrum Disorder and Dyskinesia by Luna Bajracharya, Meena Lall, Sunita Bijarnia-Mahay, Praveen Kumar, Imran Mushtaq, Pushpa Saviour, Preeti Paliwal, Anju Joshi, Shruti Agarwal, Praveen Suman

“…This case highlights a rare genetic finding and the need for timely genetic testing in a child with dysmorphism and autism with movement disorder to enable appropriate management and genetic counselling.…”
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Clinical Characteristics of Visual Dysfunction in Carbon Monoxide Poisoning Patients by Wei-Kang Bi, Jin-Lin Wang, Xu-Dong Zhou, Ze-Kun Li, Wen-Wen Jiang, Shao-Bin Zhang, Yong Zou, Ming-Jun Bi, Qin Li

“…The main ocular symptoms were local pain, eye movement disorder, and visual field defect. The key pathological factors were keratopathy, retinal nerve cell damage, optic nerve damage, retinal vascular disease, macular disease, and occipital visual center damage. …”
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Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease by Cristine de Paula Nascimento-Castro, Ana Claudia Wink, Victor Silva da Fônseca, Claudia Daniele Bianco, Elisa C. Winkelmann-Duarte, Marcelo Farina, Ana Lúcia S. Rodrigues, Joana Gil-Mohapel, Andreza Fabro de Bem, Patricia S. Brocardo

“…HD is traditionally viewed as a movement disorder, but cognitive and neuropsychiatric symptoms also contribute to the clinical presentation. …”
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A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson’s Disease by Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse, Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, Min Li

“…Outcome measures were baseline to week 32 changes in Movement Disorder Society-Sponsored Revision of Unified PD Rating Scale (MDS-UPDRS) Parts I–IV and in NMS assessment scale for PD (NMSS). …”
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Accelerated symptom improvement in Parkinson’s disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial by Alireza Gharabaghi, Sergiu Groppa, Marta Navas-Garcia, Alfons Schnitzler, Laura Muñoz-Delgado, Vicky L. Marshall, Jessica Karl, Lin Zhang, Ramiro Alvarez, Mary S. Feldman, Michael J. Soileau, Lan Luo, S. Elizabeth Zauber, Benjamin L. Walter, Chengyuan Wu, Hong Lei, Damian M. Herz, Ming-Hua Chung, Yagna Pathak, Bram Blomme, Binith Cheeran, Corneliu Luca, Daniel Weiss

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LRRK2 Mutations and Asian Disease-Associated Variants in the First Parkinson’s Disease Cohort from Kazakhstan by Rauan Kaiyrzhanov, Akbota Aitkulova, Chingiz Shashkin, Nazira Zharkinbekova, Mie Rizig, Elena Zholdybayeva, Zharkyn Jarmukhanov, Vadim Akhmetzhanov, Gulnaz Kaishibayeva, Talgat Khaibullin, Altynay Karimova, Serik Akshulakov, Askhat Bralov, Nurlan Kissamedenov, Zhanar Seidinova, Anjela Taskinbayeva, Aliya Muratbaikyzy, Henry Houlden

“…Methods. 246 PD patients were consecutively recruited by movement disorder specialists from four medical centers in Kazakhstan, and clinicodemographic data and genomic DNA from blood were systematically obtained and shipped to the Institute of Neurology University College London together with DNAs from 200 healthy controls. …”
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Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia by Mary Kay Koenig, Vincenzo Leuzzi, Riadh Gouider, Riadh Gouider, Eppie M. Yiu, Eppie M. Yiu, Barbara Pietrucha, Asbjørg Stray-Pedersen, Susan L. Perlman, Steve Wu, Trudy Burgers, Rupam Borgohain, Rukmini Mridula Kandadai, Isabelle Meyts, Giorgia Bucciol, Anaita Udwadia-Hegde, Ravi Yadav, Donna Roberts, Aaron Dane, Maureen Roden, Dirk Thye, Biljana Horn, Howard M. Lederman, William P. Whitehouse

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Author Correction: MRgFUS subthalamotomy in Parkinson’s disease: an approach aimed at minimizing Lesion Volume by Marina Campins-Romeu, Rebeca Conde-Sardón, Isabel Sastre-Bataller, Carlos Morata-Martínez, Mireya Losada-López, José Luís León-Guijarro, Luis Raga-Rodríguez, Julia Pérez-García, Antonio Gutiérrez-Martín, Andrés M. Lozano, Raquel Baviera-Muñoz, Irene Martínez-Torres

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Pisa Syndrome in Parkinson’s Disease: Electromyographic Aspects and Implications for Rehabilitation by Giuseppe Frazzitta, Pietro Balbi, Francesco Gotti, Roberto Maestri, Annarita Sabetta, Luca Caremani, Laura Gobbi, Marina Capobianco, Rossana Bera, Nir Giladi, Davide Ferrazzoli

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MRgFUS subthalamotomy in Parkinson’s disease: an approach aimed at minimizing Lesion Volume by Marina Campins-Romeu, Rebeca Conde-Sardón, Isabel Sastre-Bataller, Carlos Morata-Martínez, Mireya Losada-López, José Luís León-Guijarro, Luis Raga-Rodríguez, Julia Pérez-García, Antonio Gutiérrez-Martín, Andrés M. Lozano, Raquel Baviera-Muñoz, Irene Martínez-Torres

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A Polysomnographic Study of Parkinson’s Disease Sleep Architecture by Daniel Martinez-Ramirez, Sol De Jesus, Roger Walz, Amin Cervantes-Arriaga, Zhongxing Peng-Chen, Michael S. Okun, Vanessa Alatriste-Booth, Mayela Rodríguez-Violante

“…Only lower levodopa equivalent dose (LED) was associated with periodic limb movement disorders (PLMD). REM sleep behavior disorder (RBD) was more common among older patients, with higher MDS-UPDRS III scores, and LED. …”
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Proactive and Integrated Management and Empowerment in Parkinson’s Disease: Designing a New Model of Care by Emma Tenison, Agnes Smink, Sabi Redwood, Sirwan Darweesh, Hazel Cottle, Angelika van Halteren, Pieter van den Haak, Ruth Hamlin, Jan Ypinga, Bastiaan R. Bloem, Yoav Ben-Shlomo, Marten Munneke, Emily Henderson

“…A multidisciplinary team of professionals in the United Kingdom and the Netherlands, all with a long history of caring for patients with movement disorders, used knowledge of deficiencies with the current model of care, an understanding of integrated care in chronic disease and the process of logic modelling, to develop a novel approach to the care of patients with Parkinson’s disease. …”
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Association of a BACE1 Gene Polymorphism with Parkinson’s Disease in a Norwegian Population by Johannes Lange, Kristin Aaser Lunde, Camilla Sletten, Simon Geir Møller, Ole-Bjørn Tysnes, Guido Alves, Jan Petter Larsen, Jodi Maple-Grødem

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A Preliminary Investigation of the Running Digit Span As a Test of Working Memory by Marjan Jahanshahi, T. Saleem, Aileen K. Ho, R. Fuller, Georg Dirnberger

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