Effects of Dietary Mannan Oligosaccharides on Growth, Nonspecific Immunity and Tolerance to Salinity Stress and Streptococcus iniae Challenge in Golden Pompano, Trachinotus ovatus by Hoang Do-Huu, Hue Thi Nguyet Nguyen, Hai Thi Vo

“…Dietary MOS increased lymphocytes count (P≤0.042) and reduced monocytes and basophils counts (P≤0.019); however, no effects were found on neutrophils and eosinophil numbers (P≥0.064). …”
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CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway. by Shuaini Yang, Jinxi Yu, Xue Dong, Jiajia Zeng, Lu Tan, Hong Zhang, Ruoyuan Sun, Yuqing Tuo, Jing Yang, Chunxiao Wan, Hong Bai

“…CCR2, a member of the G protein-coupled receptor (GPCR) superfamily, is widely expressed on monocytes, macrophages, activated T cells, and other cell types, and plays a critical role in coordinating the immune response to various infections. …”
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Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita by Sana Alam, Gulnaz Afzal, Riaz Hussain, Hafiz Muhammad Ali, Amtul Sami, Rabbiah Manzoor Malik, Raheela Jabeen, Farid Shokry Ataya, Kun Li

“…Hematological analysis showed a significant (p < 0.05) increase in leukocytes and neutrophils while lymphocytes and monocytes, RBCs and hemoglobin concentration were significantly (p < 0.05) decreased. …”
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Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon by Ornella J. T. Ngalani, Armelle T. Mbaveng, Wiliane J. T. Marbou, Roland Y. Ngai, Victor Kuete

“…The average values of CD4+ T-cell count (p<0.0001), lymphocytes (p=0.0258), monocytes (p=0.0317), and total WBC count (p=0.0277) were significantly higher in HIV− patients compared to HIV+ patients. …”
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PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood by Bo Han, Qiaobo Xie, Weishi Liang, Peng Yin, Xianjun Qu, Yong Hai

“…Immune infiltration analysis found that naive CD4+ T cells and monocytes may be involved in the process of AS. PLCG2 and IFNAR1 genes were obtained by screening genes meeting the conditions of immune cell infiltration and osteoclast differentiation in AS patients among IGF2R, GRN, SH2D1A, LILRB3, IFNAR1, PLCG2, and TNFRSF1B. …”
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The potential of aloe vera gel utilization for skin wound healing in rats based on GC–MS and HPLC chemical profile by Nadia Mohamed Said Arafa, Huda Mohammad Ahmad Hummadi, Gehan Moustafa Badr

“…Results after 21 days were recorded in + ve control 80.50% wound contraction and showed significantly decreased values of IL-4, lymphocytes, Hb, RBCs and skin glycine, proline, hydroxyproline and NO. Neutrophils, monocytes, platelets and MDA were significantly increased. …”
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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

“…Using single-cell multiomics sequencing, we identify cell-specific gene expression changes associated with DNMT3A mutations, along with significant epigenomic deregulation affecting enhancer accessibility, resulting in overexpression of interleukin-32 (IL-32), a proinflammatory cytokine that can result in inflammasome activation in monocytes and macrophages. Finally, we show with single-cell resolution that the loss of function of DNMT3A is directly associated with increased chromatin accessibility in mutant cells. …”
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Strength Training Session Induces Important Changes on Physiological, Immunological, and Inflammatory Biomarkers by Ayla Karine Fortunato, Washington Martins Pontes, Débora Maria Soares De Souza, Jéssica Santos Ferreira Prazeres, Lucas Soares Marcucci-Barbosa, Júlia Miranda Mól Santos, Érica Leandro Marciano Veira, Eduardo Bearzoti, Kelerson Mauro De Castro Pinto, André Talvani, Albená Nunes Da Silva

“…Lymphocytes increased postexercise but reduced 2 h after exercise in both groups, while the number of monocytes increased only immediately after the exercise session in UTG and TG. …”
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The immunoregulatory effects of scoparone on immune-mediated inflammatory diseases by Feifei Qiu, Jingru Lin, Xiaofei Huang, Bin Yang, Weihui Lu, Weihui Lu, Zhenhua Dai, Zhenhua Dai

“…SCO has an impact on various immune cells, including mast cells, monocytes, macrophages, neutrophils and T cells, and affects a broad range of intracellular signaling pathways, including TLR4/Myd88/NFκB, TGFβR/Smad3 and JNK/Sab/SHP-1 etc. …”
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Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency by Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E. Goldfinger, Jeremy G.T. Wurtzel, Kiwon Lee, Michele P. Lambert, Mortimer Poncz, A. Koneti Rao

“…FXIII-A is synthesized by hematopoietic cells, megakaryocytes, and monocytes. Objectives: To understand RUNX1 regulation of F13A1 expression in platelets/megakaryocytes and the mechanisms and consequences of decreased F13A1 in RHD. …”
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Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…Multiparametric analysis was performed on the peripheral blood of 60 MDD patients using flow cytometry to identify lymphocytes (naïve/effector, memory, regulatory) and myeloid cells (dendritic cells, monocytes). We studied the associations between immunophenotype and depressive symptoms, social and working functioning, and subjective quality of life during the acute phase and after three months of treatment. …”
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Immune responses in rodent whole eye transplantation: elucidation and preliminary investigations into rejection diagnosis and monitoring by Bing Li, Yong Wang, Charles R. Owens, Touka Banaee, Charleen T. Chu, Kayvon Jabbari, Anna D. Lee, Neil J. Khatter, Alan G. Palestine, An-Jey A. Su, Christene A. Huang, Kia M. Washington

“…These methodologies collectively contribute to the development of non-invasive diagnostic and monitoring strategies for WET.ResultsOur study revealed a rapid and acute immune response following WET, characterized by an early innate immune response dominated by complement involvement, and infiltration of neutrophils and monocytes by post-operative day (POD) 2. This was succeeded by an acute T-cell-mediated immune reaction, predominantly involving T helper 1 (Th1) cells and cytotoxic T lymphocytes (CTLs). …”
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Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence by Xiaoyin Wu, Xiaoyin Wu, Buyu Guo, Buyu Guo, Xingyu Chang, Xingyu Chang, Yuxuan Yang, Yuxuan Yang, Qianqian Liu, Qianqian Liu, Jiahui Liu, Jiahui Liu, Yichen Yang, Yichen Yang, Kang Zhang, Yumei Ma, Songbo Fu, Songbo Fu, Songbo Fu

“…GScore was significantly associated with neutrophils and non-classical monocytes. Potential agents including esmolol, estradiol, ganciclovir, and felbamate, targeting the 12 diagnostic signatures were identified. …”
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Sickle Cell Anemia Patients Display an Intricate Cellular and Serum Biomarker Network Highlighted by TCD4+CD69+ Lymphocytes, IL-17/MIP-1β, IL-12/VEGF, and IL-10/IP-10 Axis by Nadja Pinto Garcia, Alexander Leonardo S. Júnior, Geyse Adriana S. Soares, Thainá Cristina C. Costa, Alicia Patrine C. dos Santos, Allyson Guimarães Costa, Andréa Monteiro Tarragô, Rejane Nina Martins, Flávia do Carmo Leão Pontes, Emerson Garcia de Almeida, Erich Vinícius de Paula, Olindo Assis Martins-Filho, Adriana Malheiro

“…High expression of TLR2 in monocytes and VLA-4 in TCD8+ lymphocytes and high levels of MIP-1β and RANTES appear to be relevant in high death risk conditions. …”
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Exploring the comorbidity mechanisms between atherosclerosis and hashimoto’s thyroiditis based on microarray and single-cell sequencing analysis by Yirong Ma, Shuguang Wu, Junyu Lai, Qiang Wan, Jingxuan Hu, Yanhong Liu, Ziyi Zhou, Jianguang Wu

“…Single-cell analysis demonstrated predominant expression of the core genes in macrophages, monocytes, T cells and Common Myeloid Progenitor (CMP). …”
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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, the number of MITF+ monocytic (MO)-MDSCs was examined in human tumor tissues or tumor-free lymph nodes by immunohistochemistry (IHC).Results The expression of MITF was strongly increased in MO-MDSCs from tumors of breast cancer-bearing mice compared with polymorphonuclear MDSCs. …”
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Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis by Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z

“…As a heavily glycosylated transmembrane protein, CD36 is widely expressed in diverse cell types, including placental trophoblasts, monocytes/macrophages, adipocytes, and pancreatic cells et al. …”
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Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers by Gloria Aranda, Cristina Lopez, Rebeca Fernandez-Ruiz, Yaiza Esteban, Guillermo Garcia-Eguren, Mireia Mora, Irene Halperin, Gregori Casals, Joaquim Enseñat, Felicia A. Hanzu

“…Material and Methods. 16 ACTH-dependent CS (ACTH-D), 10 ACTH-independent (ACTH-ID) CS, and 16 healthy controls (C) were included. Leukocytes (Leuc), monocytes (MN), lymphocytes (Lym), and neutrophils (N) were analyzed by flow cytometry for atherosclerosis previously associated with CDs. …”
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De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature by Venkata Rakesh Sethapati, Ra’ed Jabr, Leyla Shune, Wissam El Atrouni, Patrick R. Gonzales, Wei Cui, Shivani Golem

“…Bone marrow evaluation and flow cytometry analysis were compatible with AML with monocytic features. Cytogenetic studies revealed two-related clones, a minor clone with inv(16) and a major clone with concurrent inv(16) and t(9;22) rearrangements. …”
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Th2-Immune Polarizing and Anti-Inflammatory Properties of Insulin Are Not Effective in Type 2 Diabetic Pregnancy by Adnette Fagninou, Magloire Pandoua Nekoua, Darius Sossou, Kabirou Moutairou, Nadine Fievet, Akadiri Yessoufou

“…The frequencies of total CD3+ and CD4+ T cells and nonclassical monocytes significantly increased in insulin-treated T2D pregnant women compared to pregnant controls. …”
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