Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice by Jens J Kort, Julie L Eiseman

“…Cells of the monocyte/macrophage lineage (MM cells) are known to be infected by retroviruses, including the human immunodeficiency virus (HIV), without cytopathic changes and may serve as a persistent reservoir for the virus during the development of immunodeficiency disease. …”
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Deranged aortic intima-media thickness, plasma triglycerides and granulopoiesis in Sl/Sld mice by Kottarappat N. Dileepan, Thomas P. Johnston, Yuai Li, Ossama Tawfik, Daniel J. Stechschulte

“…Interestingly, the high-fat diet regimen elevated leukocyte counts and the number of monocytes and granulocytes in Sl/Sld mice.…”
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Boehmeria nivea Attenuates the Development of Dextran Sulfate Sodium-Induced Experimental Colitis by Eun Ju Shin, Mi Jeong Sung, Hye Jeong Yang, Myung Sunny Kim, Jin-Taek Hwang

“…In addition, EBN decreased the DSS-induced secretion of the inflammatory cytokine interleukin-6 (IL-6) and chemokine monocyte chemotactic protein-1 (MCP-1). Taken together, these data suggest that B. nivea extract is effective in preventing colitis.…”
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Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium by Fawaz Abomaray, Sebastian Gidlöf, Cecilia Götherström

“…Finally, ESC were functionally examined for their effects on monocyte differentiation into macrophages. ESCcyst and ESCendo expressed MSC markers, formed colonies, and differentiated into osteoblasts and adipocytes. …”
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Impaired Inflammatory Response to LPS in Type 2 Diabetes Mellitus by Lusine Khondkaryan, Sona Margaryan, David Poghosyan, Gayane Manukyan

“…However, innate immune responses, including monocyte functions, in T2DM are poorly investigated. …”
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Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

“…To investigate these mechanisms, triacylglycerol (TG) accumulation induced by apolipoprotein-free chylomicron remnant-like particles (CRLPw/o) in human monocyte-derived macrophages was evaluated. Macrophage TG content increased about 5-fold after incubation with CRLPw/o, and this effect was not reduced by the inhibition of phagocytosis, macropinocytosis, apolipoprotein E function, or proteoglycan bridging. …”
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Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle by A. D. Alekseev

“…The product was injected subcutaneously at a dose of 0.025 ml/kg of live weight to cows in late gestation and calves showing mild anemia, low red blood cells counts, leukocytosis, high lymphocyte and monocyte counts and elevated erythrocyte sedimentation rate, which suggest inflammatory processes in the animal body. …”
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The Mechanisms of Systemic Inflammatory and Immunosuppressive Acute-on-Chronic Liver Failure and Application Prospect of Single-Cell Sequencing by Kai Kou, Xiaodong Sun, Guangyao Tian, Yao Zhi, Zhongqi Fan, Guoyue Lv

“…Activated KCs can secrete inflammatory factors as well as chemokines and recruit bone marrow-derived cells such as neutrophils and monocytes to the liver to enhance the inflammatory process. …”
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Aging-regulated TUG1 is dispensable for endothelial cell function. by Anna Theresa Gimbel, Susanne Koziarek, Kosta Theodorou, Jana Felicitas Schulz, Laura Stanicek, Veerle Kremer, Tamer Ali, Stefan Günther, Sandeep Kumar, Hanjoong Jo, Norbert Hübner, Lars Maegdefessel, Stefanie Dimmeler, Sebastiaan van Heesch, Reinier A Boon

“…We therefore investigated if, and how, TUG1 might function in aging ECs, but despite extensive phenotyping found no alterations in basal EC proliferation, apoptosis, barrier function, migration, mitochondrial function, or monocyte adhesion upon TUG1 silencing in vitro. TUG1 knockdown did slightly and significantly decrease cumulative sprout length upon vascular endothelial growth factor A stimulation in human umbilical vein endothelial cells (HUVECs), though TUG1-silenced HUVECs displayed no transcriptome-wide mRNA expression changes explaining this effect. …”
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Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice by Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser

“…This was accompanied by a significant increase in relative monocyte and neutrophil counts and in spleen cellularity. …”
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Protective Effects of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, against Cisplatin-Induced Nephrotoxicity in Mice by Seung Hee Choi, Jaechan Leem, In-Kyu Lee

“…Gemigliptin also decreased the plasma levels of tumor necrosis factor-α and monocyte chemoattractant protein-1 and attenuated nuclear staining of nuclear factor kappa-B p65 in the kidneys. …”
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Mutual causal effects between immune cells and hepatocellular carcinoma: a Mendelian randomization study by Zheng Wang, Mengshu Pan, Jie Zhu, Changhong Liu

“…These 15 immune cells were distributed in the Monocyte (4 cells), Treg panel (4 cells), TBNK (3 cells), Maturation stages of T cell panel (3 cells), and cDC panel (1 cells). …”
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Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…In the present study, we present the time course of the patients’ plasma or serum levels of soluble markers (IL-8, IL-6, IL-10, IL-1ra, sE-selectin, PCT) and monocyte and neutrophil cell surface (CD11b, CD14, CD62L, HLA-DR) markers of systemic inflammatory response during the first 14 days after the randomization. …”
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Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway by Sang-Hoon Lee, Sung-Hwan Eom, Na-Young Yoon, Moon-Moo Kim, Yong-Xin Li, Sang Keun Ha, Se-Kwon Kim

“…An enzyme-linked immunosorbent assay and cytometric bead array assay demonstrated that FF significantly reduced the production of proinflammatory cytokines, such as interleukin-6 and tumor necrosis factor-α, and that of the monocyte chemoattractant protein-1. Moreover, FF reduced the activation of nuclear factor κB (NF-κB) and mitogen-activated protein kinases (MAPKs). …”
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Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells by Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt

“…Cathepsins are powerful elastases and collagenases secreted by endothelial cells and monocyte-derived macrophages in atherosclerosis, but their involvement in sickle cell disease has not been studied. …”
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Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2 by Naomi Kioka, Koichi Minami, Akira Tamura, Norishige Yoshikawa

“…Expression of both interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP-1) mRNA in HASTs was significantly upregulated by Stx2. …”
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Allergic Contact Dermatitis Is Associated with Significant Oxidative Stress by S. Kaur, K. Zilmer, V. Leping, M. Zilmer

“…In 40 patients, interleukin- (IL-) 6, monocyte chemoattractant protein (MCP-1), and IL-10 levels were measured in sera with the Evidence Investigator Cytokine & Growth factors High-Sensitivity Array, total peroxide concentration (TPX) and total antioxidant capacity (TAC) by means of spectrophotometry, and the plasma concentrations of adiponectin and leptin by the quantitative sandwich enzyme immunoassay technique. …”
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Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1 by Yong Li, Qi Zhang, Na Li, Liting Ding, Jinping Yi, Yue Xiao, Shibiao Chen, Xuan Huang

“…Overexpression of Ataxin-10 markedly inhibited the mRNA expressions of VCAM-1 and several cytokines including MCP-1, CXCL-1, CCL-5, and TNF-α; thus, it can also suppress monocyte adhesion to endothelial cells. Accordingly, Ataxin-10 silencing promoted endothelial inflammation. …”
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Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes by Murali Ganesan, Anup S. Pathania, Grace Bybee, Kusum K. Kharbanda, Larisa Y. Poluektova, Natalia A. Osna

“…This study was performed on HBV-replicating HepG2.2.15 cells and human monocyte-derived macrophages (MDMs). We found that exposure of HepG2.2.15 cells to an acetaldehyde-generating system (AGS) increased HBV RNA, HBV DNA, and cccDNA expressions and suppressed the activation of ISGs, <i>APOBEC3G</i>, <i>ISG15</i>, and <i>OAS1</i>. …”
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Effect of Oral and Vaginal Hormonal Contraceptives on Inflammatory Blood Biomarkers by Afshin A. Divani, Xianghua Luo, Yvonne H. Datta, James D. Flaherty, Angela Panoskaltsis-Mortari

“…We assessed the effect of hormonal contraceptive use on inflammatory cytokines including CRP, monocyte chemotactic protein-1, soluble tumor necrosis factor (sTNF), interleukin-6 (IL-6), and soluble CD40 ligand. …”
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