Elucidating the Correlation of D-Dimer Levels with COVID-19 Severity: A Scoping Review by Wesam Ahmed Nasif, Abeer Shaker El-Moursy Ali, Mohammed Hasan Mukhtar, Aali Marzouq H. Alhuzali, Yahya Ahmed Yahya Alnashri, Ziyad Ishaq Ahmed Gadah, Eyyad Adeeb A. Edrees, Hussam Abdulaziz Mabruk Albarakati, Hussam Saud Muhji Aloufi

“…A D-dimer is a complex protein molecule that is formed during plasmin-mediated degradation of the fibrin network. …”
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VCAM-1 Promotes Angiogenesis of Bone Marrow Mesenchymal Stem Cells Derived from Patients with Trauma-Induced Osteonecrosis of the Femoral Head by Regulating the Apelin/CCN2 Pathway by Yiming Shao, Lei Sun, Baodong Ma, Ranran Jin, Yueyao Ban, Ruibo Li, Jianfa Wang, Hongkai Lian, Han Yue

“…Vascular cell adhesion molecule 1 (VCAM-1) has been shown to have potent proangiogenic activity, but the role in angiogenesis of TI-ONFH is unclear. …”
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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

“…The induction of genes associated with pectin degradation, adhesion, and colonization was notable during the early infection phase, whereas during the necrotrophic phase, some structural molecule activity-related genes were prominently induced. …”
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Development of a Simple and Powerful Analytical Method for Formaldehyde Detection and Quantitation in Blood Samples by Yong-Hyun Kim, Jeongsik Park

“…The pretreated samples were analyzed using a high-performance liquid chromatography-UV system, which is the most common choice for analyzing small-molecule aldehydes like formaldehyde. Verification of the pretreatment methods (stabilization and derivatization) using FA standards confirmed that the pretreatment methods are highly reliable in the calibration range 0.012–5.761 ng μL–1 (slope = 684,898, R2 = 0.9998, and limit of detection = 0.251 pg·μL–1). …”
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Pooled PPIseq: Screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform. by Darach Miller, Adam Dziulko, Sasha Levy

“…At higher scales, viral-host PPI screening could also be used to screen for small-molecule antivirals that interfere with essential viral-host interactions, or to explore how the PPI networks between interacting viral and host genomes co-evolve. …”
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Restoration of Genetic Code in Macular Mouse Fibroblasts via APOBEC1-Mediated RNA Editing by Sonali Bhakta, Hiroko Kodama, Masakazu Mimaki, Toshifumi Tsukahara

“…RNA editing is a significant mechanism underlying genetic variation and protein molecule alteration; C-to-U RNA editing, specifically, is important in the regulation of mammalian genetic diversity. …”
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Disrupted Endothelial Cell Layer and Exposed Extracellular Matrix Proteins Promote Capture of Late Outgrowth Endothelial Progenitor Cells by Jing Zhao, Claudia-Gabriela Mitrofan, Sarah L. Appleby, Nicholas W. Morrell, Andrew M. L. Lever

“…The interaction was not adhesion molecule-dependent and not enhanced by EC activation. …”
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A Chromosomal-Level Genome of Dermatophagoides farinae, a Common Allergenic Mite Species by Rongxuan Hu, Haifeng Huang, Ying Zhou, Yanshan Liu, Yaning Ren, Yuanfen Liao, Cunyin Yuan, Xiaohong Gu, Yubao Cui

“…We achieved a chromosome-level assembly of D. farinae’s genome by integrating PacBio single-molecule real-time sequencing, Illumina paired-end sequencing, and Hi-C technology, followed by annotating allergens and mapping them to specific chromosomes. …”
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Nano‐pyrite as a plant hormone regulator: Emulating seed hormopriming by Brijesh Kaler, Himanshi Jangir, Sabyasachi Sarkar, Jayprakash Sharma, Mainak Das

“…Recently, several nanomaterials have emerged as economical seed and root priming agents, with nanoiron pyrite standing out as a particularly promising molecule. The observed enhancement in germination of nano‐pyrite treated seeds across various plant species indicate a shared underlying mechanism. …”
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Structural modeling of NAD+ binding modes to PARP-1 by N. V. Ivanisenko, D. A. Zhechev, V. A. Ivanisenko

“…The structure of complex of human poly (ADP-ribose) polymerase-1 with NAD+ can be a starting point for rational design of small molecule inhibitors based on NAD+ derivatives. Indeed there is no crystal structure of complex poly (ADP-ribose) polymerase-1 with nicotinamide adenine dinucleotide (NAD+) available yet. …”
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Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

“…JNK and p38 MAPK activation contributes to myocardial IR injury after prolonged hypothermic storage. p38 MAPK inhibition improves cardiac function after cold storage, rewarming and reperfusion. Small-molecule p38 MAPK inhibitors have been tested clinically in patients with chronic inflammatory diseases, but not in transplanted patients, so far. …”
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Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy by Alireza Shoari, Arghavan Ashja Ardalan, Alexandra M. Dimesa, Mathew A. Coban

“…We also critically evaluate recent advancements in the development of gelatinase inhibitors, including small molecule inhibitors, natural compounds, and novel therapeutic approaches like gene silencing techniques. …”
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Cinnamaldehyde impacts key cellular signaling pathways for induction of programmed cell death in high-grade and low-grade human glioma cells by Yoo Na Kim, Ketki Patil, S. Balakrishna Pai

“…Notably, the cell survival/death pivotal molecule Bcl-2 was impacted. These effects were observed in both the types of brain tumor cells studied: GBMs, represented by U251 cells (p53 mutated cell line) and LGGs represented by H4 cells. …”
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New insights into the DNA extraction and PCR amplification of minute ascomycetes in the genus Laboulbenia (Pezizomycotina, Laboulbeniales) by Warre Van Caenegem, Danny Haelewaters

“…This is attributed to the presence of melanin, a molecule known to inhibit PCR, in the cells. We evaluated the efficacy of a standard single cell-based DNA extraction protocol by halving the recommended amount of reagents to reduce the cost per extraction and adding bovine serum albumin (BSA) during the multiple displacement amplification step to reverse the effect of melanin. …”
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Hydroxymethylfurfural in honey: a public health problem by Bruno Soares Toledo, Lévison da Costa Cipriano, Thais Regina de Castro Pereira, Sérgio Borges Mano, Adriano Gomes da Cruz, Erick Almeida Esmerino, Eliane Teixeira Mársico

“…Due to its composition can form a compound called 5-hydromethylfurfural or HMF (a furanic ring with functional groups of aldehyde and alcohol), classified as an organic molecule produced from the degradation of sugar after the Maillard reaction that has harmful effects on consumer´s healthy. …”
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Quorum sensing-mediated inter-specific conidial anastomosis tube fusion between Colletotrichum gloeosporioides and C. siamense by Nikita Mehta, Abhishek Baghela

“…This CAT fusion involved a quorum sensing phenomenon, wherein the CAT induction was dependent on conidial density and the putative quorum sensing molecule was extractable in chloroform. Movement of nuclei, mitochondria, and lipid droplets were observed during the CAT fusion. …”
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Insight into unusual complex thermodynamical behaviour of citric acid and ethanolamine solution by Reshma Karunakaran, Rajagopal Shanmugasundaram

“…This paper reports the IFF phenomenon with basic chemicals such as citric acid and ethanolamine subjected to different conditions. The amine molecule within the precursor compound is crucial in attaining this phenomenon. …”
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Effect of preparation method in the properties of iron oxide catalysts for fenton reaction by Fabiana Maria Barbosa, Andre Rosa Martins

“… This work discusses methods of preparing iron oxide for the Fenton reaction, using methylene blue as a model molecule. The solids were prepared by precipitation, complexation, combustion, and decomposition and characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electronic microscopy, energy dispersive X-ray spectroscopy, specific surface area measurement and were evaluated for methylene blue removal. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…The identification of the active molecule/s in the chloroform extract will serve as drug candidate for colorectal carcinoma. …”
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Adsorption removing various basic nitrogen compounds from model diesel over allochroic silica gel by Xin Hong, Yunhe Li, Chang Gao, Yonghua Zhao, Ke Tang

“…The N–Co bond between Co in allochroic silica gel and N atom in the basic nitrogen compounds molecule played a significant role. Furthermore, the allochroic silica gel could be easily regenerated by its adsorption denitrogenation performance for quinoline and pyridine by using calcination once or several times, except aniline. …”
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