Immune Regulation and Antitumor Effect of TIM-1 by Peng Du, Ruihua Xiong, Xiaodong Li, Jingting Jiang

“…T cells play an important role in antitumor immunity, and the T cell immunoglobulin domain and the mucin domain protein-1 (TIM-1) on its surface, as a costimulatory molecule, has a strong regulatory effect on T cells. …”
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On the Resistance-Harary Index of Graphs Given Cut Edges by Hongzhuan Wang, Hongbo Hua, Libing Zhang, Shu Wen

“…Each vertex in the graph represents the molecule and each edge represents the bond between the atoms. …”
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Studies of axially chiral atropisomers of an indole-substituted phthalonitrile derivative by Ayari, Sami, Elleuch, Haitham, Thebti, Amal, Ouzari, Hadda-Imene

“…Structural confirmation of the molecule was achieved using 1H, 13C NMR and mass spectroscopy. …”
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A Study of the Electronic Absorption and Emission Spectra of DBDMA Dye: Solvent Effect, Energy Transfer, and Fluorescence Quenching by Sadeq M. Al-Hazmy, Jameelah Al-Harby, Mohammed Hassan, Sabri Messaoudi, Ibrahim A. Alhagri, Ahmed N. Alhakimi

“…The rigidity of the DBDMA molecule is the main reason for the photochemical stability and the absence of a considerable shift as a result of the change in the polarity of the solvents. …”
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Analysis of the Cytokine Expression in the Aqueous Humor of Individuals with BRVO-Associated Macular Edema by Chengyi Zhu, Lanlan Pan, Qiong Yi, Qiping Wei

“…This study aimed to determine the expression levels of vascular endothelial growth factor (VEGF), interleukin-6 (IL-6), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in the aqueous humor of patients with macular edema (ME) caused by branch retinal vein occlusion (BRVO), as well as to investigate the relationship between the cytokines as mentioned earlier and best-corrected visual acuity (BCVA), ME, and the degree of ME from the molecular level. …”
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Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation by Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia

“…This approach might be helpful to understand the selectivity of the given drug molecule in the treatment of Alzheimer's disease. The study provides evidence for consideration of C28H34N2O6 as a valuable small ligand molecule in treatment and prevention of AD associated disorders and further in vitro and in vivo investigations may prove its therapeutic potential.…”
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Identification of a Novel PPAR Signature for Predicting Prognosis, Immune Microenvironment, and Chemotherapy Response in Bladder Cancer by Ke Zhu, Wen Deng, Hui Deng, Xiaoqiang Liu, Gongxian Wang, Bin Fu

“…Moreover, 11 candidate small molecule drugs were identified for the treatment of BLCA. …”
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Unveiling the role of SYNGR4 in breast cancer development: a novel target for immunotherapy by Jie Ma, Hongtao Wang, Zhengwei Gui, Yuanrong Yang

“…The effect of SYNGR4 on breast cancer prognosis was analyzed using bioinformatics and possible pathways by which this molecule affects breast cancer prognosis were explored. …”
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Methane Adsorption in Anthracite Coal under Different Pressures and Temperatures—A Study Combining Isothermal Adsorption and Molecular Simulation by Tieya Jing, Jian Zhang, Mingyu Zhu, Wentao Zhao, Juan Zhou, Yulong Yin

“…Carbons connected to the oxygen atoms contribute 13.7% of the total carbons in coal molecule, and the oxygen atoms are mainly in the form of carbonyl. …”
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Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on P... by Mpho Ndou, Marthe C. D. Fotsing, Michael H. K. Kengne, Edwin M. Mmutlane, Derek T. Ndinteh, Mthokozisi B.C. Simelane, Lesetja Motadi, Mpho Choene

“…The study suggests that the study molecule can be a promising chemotherapeutic agent in the development of new anticancer drugs. …”
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A Novel Fluorescent Chemosensor Based on Rhodamine Schiff Base: Synthesis, Photophysical, Computational and Bioimaging Application in Live Cells by Oyedoyin Aduroja, Roosevelt Shaw, Sisay Uota, Isaac Abiye, James Wachira, Fasil Abebe

“…Colorimetric and photophysical studies have demonstrated that the molecule produced can selectively sense Pb²⁺ and Cu²⁺ ions in a solution of CH₃CN/H₂O (9:1, <i>v</i>/<i>v</i>). …”
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Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound by Do Won Hwang, Hyun Woo Kwon, Jaeho Jang, Hee Jung Jung, Kwang Rok Kim, Dong Soo Lee

“…This method would help further our understanding of the differentiation of MSCs to produce neurons by simple treatment of small molecule.…”
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Novel Organotin(IV) Schiff Base Complexes with Histidine Derivatives: Synthesis, Characterization, and Biological Activity by Ariadna Garza-Ortiz, Carlos Camacho-Camacho, Teresita Sainz-Espuñes, Irma Rojas-Oviedo, Luis Raúl Gutiérrez-Lucas, Atilano Gutierrez Carrillo, Marco A. Vera Ramirez

“…The spectroscopic evidence shows two types of structures: a trigonal bipyramidal stereochemistry with the tin atom coordinated to five donating atoms (two oxygen atoms, one nitrogen atom, and two carbon atoms belonging to the alkyl moieties), where one molecule of ligand is coordinated in a three dentate fashion. …”
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Selenoprotein S Attenuates Tumor Necrosis Factor-α-Induced Dysfunction in Endothelial Cells by Siyuan Cui, Lili Men, Yu Li, Yingshuo Zhong, Shanshan Yu, Fang Li, Jianling Du

“…Furthermore, SelS overexpression blocks the TNF-α-induced adhesion of THP-1 cells to HUVECs and inhibits the increase in intercellular adhesion molecule-1 and vascular cell adhesion molecule-1. Moreover, SelS overexpression regulates TNF-α-induced inflammatory factors including interleukin-1β, interleukin-6, interleukin-8, and monocyte chemotactic protein-1 and attenuates the TNF-α-induced activation of p38 mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) pathways. …”
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MARVEL Analysis of the Measured High-resolution Spectra of 12C16O by Salman Mahmoud, Nayla El-Kork, Nariman Abu Elkher, Mubarak Almehairbi, Malathe Samir Khalil, Tibor Furtenbacher, Attila G. Császár, Olga P. Yurchenko, Sergey N. Yurchenko, Jonathan Tennyson

“…The Measured Active Rotational–Vibrational Energy Levels (MARVEL) algorithm is used to determine accurate empirical rotational–vibrational energy levels for the ground electronic state of the diatomic ^12 C ^16 O molecule. 2293 energy levels have been obtained through a careful analysis of lines measured and assigned in high-resolution experimental spectra reported previously in 68 publications. …”
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Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery by Francisco Javier Hermoso-Pinilla, Aitor Valdivia, María-José Camarasa, Tiziana Ginex, Francisco Javier Luque

“…The final section will be dedicated to elucidating novel and promising antiviral strategies proceeding from the transformation of known small molecule antivirals in proteolysis targeting chimera (PROTAC)-based targeted protein degradation. …”
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New Investigation of Millimeter-Wave Rotational Spectrum of CF3CN in the Excited Vibrational States v7=1 and v8=1 by Masoud Motamedi, Bahram Vahabzadeh Zargari

“…The millimeter-wave rotational spectra of the excited vibrational states v7=1 and v8=1 of the symmetric top molecule trifluoroacetonitrile, CF3CN, have been analyzed again. …”
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Role of NKT Cells in the Pathogenesis of NAFLD by Kazuto Tajiri, Yukihiro Shimizu

“…Those processes are thought to depend on interaction between NKT cells and CD1d molecule in the liver.…”
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Animal Models of Diabetes and Related Metabolic Diseases by Tomohiko Sasase, Fatchiyah Fatchiyah, Katsuhiro Miyajima, Masayo Koide

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Safety and efficacy of an Anti-CD20 Monoclonal antibody (RedituxTM) In Indian patients with seropositive rheumatoid arthritis by Arun Hegde, Vivek Vasdev, Krishnan Shanmuganandan, Kavita Singh, Sivasami Kartik, Abhishek Kumar

“…Limited data are available about the safety and efficacy of biosimilar version of this molecule. In this study, we assessed the clinical efficacy and safety profile of biosimilar RTX, RedituxTM. …”
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