Extend Plastron Longevity on Superhydrophobic Surface Using Gas Soluble and Gas Permeable Polydimethylsiloxane (PDMS) by Ankit Gupta, Hangjian Ling

“…However, the longevity of the plastron is significantly affected by gas diffusion, a process where gas molecules slowly diffuse into the ambient liquid. In this work, we demonstrated that plastron longevity could be extended using a gas-soluble and gas-permeable polydimethylsiloxane (PDMS) surface. …”
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The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome by Si Cheng, Haibo Wang, Hong Zhou

“…However, TLR4 provides a third signal for B cell activation and then promotes B cells better receiving signals from both B cell antigen receptor (BCR) and CD40, thus promoting B cell activation, surface molecules expression, anti-β2GPI Ab production, and cytokines secretion and making B cell functioning like an antigen presenting cell (APC). …”
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Do cytokines play a role in the transition from acute to chronic musculoskeletal pain? by Andrea Ebersberger, Hans-Georg Schaible

“…Possible mechanisms for the development of such pain states are often reflected in inflammatory or neuropathic processes involving, among others, cytokines and other molecules. Since biologics such as blockers of TNF or IL-6 can attenuate inflammation and pain in a subset of patients with rheumatoid arthritis, the question arises to what extent cytokines are involved in the generation of pain in human musculoskeletal diseases. …”
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Effects of α-ZrP on Crystallinity and Flame-Retardant Behaviors of PA6/MCA Composites by Yuanfang Xiao, Jiayou Xu, Siwen Huang, Haiming Deng

“…MCA-α-ZrP were synthesized through the self-assembly of α-ZrP, Melamine (ME), and cyanuric acid (CA) molecules. The results of differential scanning calorimetry (DSC) and X-ray diffraction (XRD) showed that the incorporation of enough α-ZrP (30 wt% MCA) caused the increased crystallinity of PA6 and tended to form γ phase. …”
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Accurate measurements of slice electron beam parameters at the undulator in seeded free-electron lasers by Enrico Allaria, Paolo Cinquegrana, Miltcho B. Danailov, Eugenio Ferrari, Fabian Pannek, Giuseppe Penco, Eleonore Roussel, Carlo Spezzani

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In silico identification of switching nodes in metabolic networks by Mairet, Francis

“…A major challenge to better understand metabolic regulation is to identify, from the hundreds or thousands of molecules, the key metabolites where the re-orientation of fluxes occurs. …”
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Lithocholic acid controls adaptive immune responses by inhibition of Th1 activation through the Vitamin D receptor. by Thijs W H Pols, Teresa Puchner, H Inci Korkmaz, Mariska Vos, Maarten R Soeters, Carlie J M de Vries

“…Bile acids are established signaling molecules next to their role in the intestinal emulsification and uptake of lipids. …”
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Efficient F Labeling of Cysteine-Containing Peptides and Proteins Using Tetrazine–-Cyclooctene Ligation by Shuanglong Liu, Matthew Hassink, Ramajeyam Selvaraj, Li-Peng Yap, Ryan Park, Hui Wang, Xiaoyuan Chen, Joseph M. Fox, Zibo Li, Peter S. Conti

“…However, the short half-life of 18 F and the poor nucleophilicity of fluoride introduce challenges for the incorporation of 18 F into complex molecules. Recently, the tetrazine- trans -cyclooctene ligation was introduced as a novel 18 F labeling method that proceeds with fast reaction rates without catalysis. …”
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Knowledge on the Use of Biosimilars in Hematological Malignancies Amongst Health Care Workers at a Tertiary Hospital in Northeast Nigeria by Rufai A. Dachi, Mustapha S. Umar, Maryam Mahdi, Nura H. Alkali, Falmata G. Mustapha, Fatima M. Muhammad, Alhaji Abdu

“…Their treatments have been revolutionized using biological molecules (biologics and biosimilars). These novel agents are used in the care of cancer patients and have significantly improved survival. …”
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Green Biosynthesis of Silver Nanoparticles from Moringa oleifera Leaves and Its Antimicrobial and Cytotoxicity Activities by Gufran Mahmood Mohammed, Sumaiya Naeema Hawar

“…Fourier transform infrared analysis shows the possible interactions between silver and bioactive molecules in Moringa oleifera leaves extracts, which may be responsible for the synthesis and stabilization of silver nanoparticles. …”
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Production of HMF-derivatives from wine residues using Saccharomyces cerevisiae as whole-cell biocatalyst by Joana T. Cunha, Aloia Romaní, Lucília Domingues

“…Transitioning to a bio-based economy requires prioritizing chemical production processes that utilize renewable resources, ensuring sustainability and environmental responsibility. 5-Hydroxymethylfurfural (HMF) and its derivatives are promising building blocks, ranked among the top 12 bio-based molecules derived from biomass. This study investigates the potential of wine residues as substrates for HMF production and explores the yeast Saccharomyces cerevisiae, a robust industrial microbial cell factory, as a whole-cell biocatalyst for converting HMF into high-value compounds, offering an alternative to chemical synthesis. …”
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Protonation and Solvation Thermodynamics of Some Naphthol Derivatives in KCl Aqueous Solution of Different Ionic Strengths by Farid I. El-Dossoki

“…The results reveal that naphthalen-1-ol and naphthalene-1,5-diol molecules have two ionisable protons (of the hydroxyl groups) while 4-amino-3-hydroxynaphthalene-1-sulphonic acid has three ionisable protons (hydrogen ion of the hydroxyl group, SO3H, and NH3+). …”
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Structural evolution characteristics of sulfur in coal during gold-tube thermal simulation by Liping Xue, Yuegang Tang, Shuo Gao

“…At Easy%Ro = 1.75, small molecules of free organic sulfur are most abundant in coal. …”
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Exosomes Regulate the Transformation of Cancer Cells in Cancer Stem Cell Homeostasis by Jiasheng Xu, Kaili Liao, Weimin Zhou

“…Exosomes, as extracellular vesicles, participate in physiological and pathological processes by transmitting signaling molecules such as proteins, nucleic acids, and lipids. …”
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Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis by N. V. Basov, A. V. Adamovskaya, A. D. Rogachev, E. V. Gaisler, P. S. Demenkov, T. V. Ivanisenko, A. S. Venzel, S. V. Mishinov, V. V. Stupak, S. V. Cheresiz, O. S. Oleshko, E. A. Butikova, A. E. Osechkova, Yu. S. Sotnikova, Y. V. Patrushev, A. S. Pozdnyakov, I. N. Lavrik, V. A. Ivanisenko, A. G. Pokrovsky

“…Pathway analysis using the KEGG database, conducted with MetaboAnalyst 6.0, revealed a statistically sig­nificant overrepresentation of sphingolipid metabolism, suggesting a critical role of these lipid molecules in glio­blastoma pathogenesis. Using computational systems biology and artificial intelligence methods implemented in a cognitive platform, ANDSystem, molecular genetic regulatory pathways were reconstructed to describe potential mechanisms underlying the dysfunction of sphingolipid metabolism enzymes. …”
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The Expression Pattern and Functional Analysis of Extracellular Vesicle Long Non-Coding RNAs from Uterine Fluid During Implantation in Pig by Yijun Shang, Qiuping Zhang, Yue Ding, Yongzhong Wang, Shengchen Gu, Xupeng Zang, Zheng Xu, Sixiu Huang, Zicong Li, Zhenfang Wu, Ting Gu, Linjun Hong, Gengyuan Cai

“…Extracellular vesicles (EVs) in the uterine fluid (UF) can target and deliver maternal endometrial signalling molecules to embryonic trophoblast cells, exerting crucial regulatory effects during embryo implantation. …”
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Surface topography modulates initial platelet adhesion to titanium substrata by Cecilia Yan Guo, Raymond Mo, Hugh Kim

“…In addition, the secretion of critical molecules stored in platelet granules (platelet factor 4, PF4; soluble P-selectin, sCD62P; transforming growth factor-beta1, TGF-β1; platelet-derived growth factor-AB, PDGF-AB) was measured by enzyme-linked immunosorbent assay (ELISA) analysis of the supernatants. …”
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Screening of multi deep learning-based de novo molecular generation models and their application for specific target molecular generation by Yishu Wang, Mengyao Guo, Xiaomin Chen, Dongmei Ai

“…With the development of deep learning techniques for the de novo generation of molecules, also known as inverse molecular design, the increasingly widespread application of various types of deep learning algorithms has led to revolutionary changes in de novo molecular generation research. …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

“…Extracellular vesicles (EVs) carry bioactive molecules in the same way as their originating cells and are more stable and considered much safer than cells for therapies. …”
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The role of lipids and lipids lowering drugs in human papillomavirus (HPV) and HPV-associated cancers by Ehsan Shabani, Aida Hasanzadi, Omer Qutaiba B. Allela, Radhwan Abdul Kareem, Riyad E. Abed, Ali M. Ali Al-Nuaimi, Zainab H. Athab, Shiva Khodarahmi

“…One of the most noticeable metabolic abnormalities in cancer is lipid metabolism reprogramming, in which cancer cells dysregulate lipid metabolism to obtain sufficient energy, building blocks for cell membranes, and signaling molecules necessary for invasion, metastasis, proliferation, and survival. …”
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