The role of CXCL12/CXCR4/CXCR7 axis in cognitive impairment associated with neurodegenerative diseases by Rojin Sarallah, Shima Jahani, Alireza Soltani Khaboushan, Amir Kian Moaveni, Maryam Amiri, Masoumeh Majidi Zolbin

“…The: Cysteine-X-cysteine chemokine ligand 12(CXCL12)/CXC chemokine receptor type 4 (CXCR4)/CXC chemokine receptor type 7 (CXCR7) axis has emerged as a critical molecular pathway in the development of CI in these disorders. …”
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<i>Pleurotus ostreatus</i>: Nutritional Enhancement and Antioxidant Activity Improvement Through Cultivation on Spent Mushroom Substrate and Roots of Leafy Vegetables by Eirini-Maria Melanouri, Ilias Diamantis, Marianna Dedousi, Eleni Dalaka, Paraskevi Antonopoulou, Seraphim Papanikolaou, Ioannis Politis, Georgios Theodorou, Panagiota Diamantopoulou

“…This study also enhances our knowledge by which SMS and RLV influence the NFE2L2/HMOX-1 molecular pathway, thereby affecting specific antioxidant-related genes. …”
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Chromosome-level reference genome and annotation of the Arctic fish Anisarchus medius by Ruoyu Liu, Ziyu Meng, Yinan Mu, Ran Zhang, Hanhui Ma, Jingjing Hu, Yanan Wang, Yuxin Shi, Yanan Li, Chaofeng Wang, Weini Zhang, Longshan Lin, Ping Zheng, Xinhua Chen

“…A total of 30,345 protein-coding genes were identified, encoding 46,603 proteins, with a BUSCO completeness of 94.98%. Molecular pathway related to the endocrine system, carbohydrate metabolism, folding, sorting, and degradation, signal transduction, and transport and catabolism contribute to A. medius adaptation to extreme Arctic environments. …”
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Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901 by Zhiying Ai, Jingjing Shao, Xinglong Shi, Mengying Yu, Yongyan Wu, Juan Du, Yong Zhang, Zekun Guo

“…Embryonic stem cells (ESCs) have the ability to grow indefinitely and retain their pluripotency in culture, and this self-renewal capacity is governed by several crucial molecular pathways controlled by specific regulatory genes and epigenetic modifications. …”
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PPARG Could Work as a Valid Therapeutic Strategy for the Treatment of Lung Squamous Cell Carcinoma by Shunbin Shi, Guiping Yu, Bin Huang, Yedong Mi, Yan Kang, Julia Pia Simon

“…Then, literature-based molecular pathways between PPARG and LSCC were established. …”
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14-3-3 Proteins in Glutamatergic Synapses by Jiajing Zhang, Yi Zhou

“…A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.…”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

“…However, the shared genetic signatures and molecular pathways underlying these two conditions remain elusive. …”
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Inflammation in Retinal Vein Occlusion by Avnish Deobhakta, Louis K. Chang

“…A number of more recent laboratory and clinical studies have begun to elucidate the role inflammation may play in the molecular pathways responsible for the vision-impairing consequences of retinal vein occlusion, such as macular edema. …”
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Aortic Disease in the Young: Genetic Aneurysm Syndromes, Connective Tissue Disorders, and Familial Aortic Aneurysms and Dissections by Marcelo Cury, Fernanda Zeidan, Armando C. Lobato

“…In this study, we propose the review of the current genetic knowledge in the aortic disease, observing, in the results that the causative genes and molecular pathways involved in the pathophysiology of aortic aneurysm disease remain undiscovered and continue to be an area of intensive research.…”
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Protocol for generating liver metastasis microtissues to decipher cellular interactions between metastatic intestinal cancer and liver tissue by Maria Lamprou, Ana Krotenberg Garcia, Saskia Jacoba Elisabeth Suijkerbuijk

“…Cancer cells exploit these mechanisms for expansion, but the underlying molecular pathways remain elusive. Here, we present a protocol for generating matrix-free microtissues recapitulating cellular interactions between intestinal cancer and hepatocyte-like cells using microscopy or transcriptomics/proteomics. …”
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Role of B-Cell Lymphoma/Leukemia 11A in Normal and Malignant Hematopoiesis by Haihang Zhang, Junhao Zeng, Fangling Zhang, Jing Liu, Long Liang

“…The dysregulation of BCL11A disrupts downstream molecular pathways, contributing to the development of several hematological malignancies, particularly leukemias. …”
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Convergence of evolving artificial intelligence and machine learning techniques in precision oncology by Elena Fountzilas, Tillman Pearce, Mehmet A. Baysal, Abhijit Chakraborty, Apostolia M. Tsimberidou

“…By analyzing multi-dimensional, multiomic, spatial pathology, and radiomic data, these technologies enable a deeper understanding of the intricate molecular pathways, aiding in the identification of critical nodes within the tumor’s biology to optimize treatment selection. …”
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Molecular Pathogenesis of Cholangiocarcinoma by G. Fava, I. Lorenzini

“…This Paper describes the scientific progresses made in the last years in defining the molecular pathways implicated in the generation of this devastating disease.…”
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A structural model of the VEGF signalling pathway: Emergence of robustness and redundancy properties by Floriane Lignet, Vincent Calvez, Emmanuel Grenier, Benjamin Ribba

“…In this paper, we propose a structural model of the main molecular pathways involved in the endothelial cells response to VEGF stimuli. …”
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Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming by Androniki Kretsovali, Christiana Hadjimichael, Nikolaos Charmpilas

“…Here we review the molecular pathways that are involved in the functions of HDAC inhibitors on stem cell differentiation and reprogramming of somatic cells into pluripotency. …”
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Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence by Nicola Alessio, Tiziana Squillaro, Giovanni Di Bernardo, Giovanni Galano, Roberto De Rosa, Mariarosa AB Melone, Gianfranco Peluso, Umberto Galderisi

“…We then analyzed how genotoxic stressors may promote the release of IGFBP-4 and the molecular pathways associated with the induction of senescence by this protein.…”
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Emerging Roles of Synapse Organizers in the Regulation of Critical Periods by Adema Ribic, Thomas Biederer

“…The synaptic specificity of these processes points towards the involvement of distinct molecular pathways. Attractive candidates are pre- and postsynaptic transmembrane proteins that form adhesive complexes across the synaptic cleft. …”
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Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting by GV Naveen Kumar, Rui-Sheng Wang, Ankit X. Sharma, Natalie L. David, Tânia Amorim, Daniel S. Sinden, Nandini K. Doshi, Martin Wabitsch, Sebastien Gingras, Asim Ejaz, J. Peter Rubin, Bradley A. Maron, Pouneh K. Fazeli, Matthew L. Steinhauser

“…Abstract Physiological adaptations to fasting enable humans to survive for prolonged periods without food and involve molecular pathways that may drive life-prolonging effects of dietary restriction in model organisms. …”
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Proteomic dataset of sorghum leaf and root responses to single and combined drought and heat stress by Ali Elnaeim Elbasheir Ali, Robert E. Sharp, Laura Greeley, Scott C. Peck, David L. Tabb, Ndiko Ludidi

“…GO and KEGG annotation revealed biological processes and molecular pathways associated with sorghum responses to these treatments. …”
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Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes by Gina Manda, Alexandru-Ionel Checherita, Maria Victoria Comanescu, Mihail Eugen Hinescu

“…It highlights key molecular pathways and new hypothesis in diabetic nephropathy, related to the interferences of metabolic, oxidative, and inflammatory stresses. …”
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