Genes Induced by Panax Notoginseng in a Rodent Model of Ischemia-Reperfusion Injury by Lanqing Meng, Qing Huang, Xuebin Li, Ping Liang, Yueyong Li, Xiaohua Huang, Jingjie Zhao, Qiuping Chen, Rong Qiu, Lan Li, Chongdong Jian, Hongfei Yao, Jianmin Huang, Xionglin Tang, Zechen Wang, Zhongheng Wei, Jun Wu, Liuzhi Wei, Qiuju Wei, Qianli Tang, Lu Huang, Jihua Wei, Dinggui Lu, Qunqiang Luo, Kegong Xie, Yang Ouyang, Jian Chen, Genliang Li, Linxue Luo, Linbo He, Chenyi Zhuo, Anding Xu, Lingzhang Meng

Get full text

A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma by Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner

Get full text

Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

Get full text

Rapid molecular assays versus blood culture for bloodstream infections: a systematic review and meta-analysisResearch in context by Gabriella Anna Rapszky, Uyen Nguyen Do To, Veronika Eszter Kiss, Tamás Kói, Anna Walter, Dorottya Gergő, Fanni Adél Meznerics, Márton Rakovics, Szilárd Váncsa, Lajos Vince Kemény, Dezső Csupor, Péter Hegyi, Michael R. Filbin, Csaba Varga, Bánk G. Fenyves

Get full text

HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis by Hong Wang, Dong Qian, Jiabei Wang, Yao Liu, Wenguang Luo, Hongyan Zhang, Jingjing Cheng, Heng Li, Yang Wu, Wuhan Li, Jing Wang, Xia Yang, Tianzhi Zhang, Dong Han, Qinyao Wang, Chris Zhiyi Zhang, Lianxin Liu

Get full text

Expression‐based machine learning models for predicting plant tissue identity by Sourabh Palande, Jeremy Arsenault, Patricia Basurto‐Lozada, Andrew Bleich, Brianna N. I. Brown, Sophia F. Buysse, Noelle A. Connors, Sikta Das Adhikari, Kara C. Dobson, Francisco Xavier Guerra‐Castillo, Maria F. Guerrero‐Carrillo, Sophia Harlow, Héctor Herrera‐Orozco, Asia T. Hightower, Paulo Izquierdo, MacKenzie Jacobs, Nicholas A. Johnson, Wendy Leuenberger, Alessandro Lopez‐Hernandez, Alicia Luckie‐Duque, Camila Martínez‐Avila, Eddy J. Mendoza‐Galindo, David Cruz Plancarte, Jenny M. Schuster, Harry Shomer, Sidney C. Sitar, Anne K. Steensma, Joanne Elise Thomson, Damián Villaseñor‐Amador, Robin Waterman, Brandon M. Webster, Madison Whyte, Sofía Zorilla‐Azcué, Beronda L. Montgomery, Aman Y. Husbands, Arjun Krishnan, Sarah Percival, Elizabeth Munch, Robert VanBuren, Daniel H. Chitwood, Alejandra Rougon‐Cardoso

Get full text

AdipoRon ameliorates the progression of heart failure with preserved ejection fraction via mitigating lipid accumulation and fibrosis by Wuping Tan, Yijun Wang, Siyi Cheng, Zhihao Liu, Mengjie Xie, Lingpeng Song, Qinfang Qiu, Xiaofei Wang, Zeyan Li, Tianyuan Liu, Fuding Guo, Jun Wang, Xiaoya Zhou

“…Cardiac function was evaluated using echocardiography, and Postmortem analysis included RNA-sequencing, untargeted metabolomics, transmission electron microscopy and molecular biology methods. Results: Our study presents the pioneering evidence that AdipoR was downregulated and impaired fatty acid oxidation in the myocardia of HFpEF mice, which was associated with lipid metabolism as indicated by untargeted metabolomics. …”
Get full text

A split-GAL4 driver line resource for Drosophila neuron types by Geoffrey W Meissner, Allison Vannan, Jennifer Jeter, Kari Close, Gina M DePasquale, Zachary Dorman, Kaitlyn Forster, Jaye Anne Beringer, Theresa Gibney, Joanna H Hausenfluck, Yisheng He, Kristin Henderson, Lauren Johnson, Rebecca M Johnston, Gudrun Ihrke, Nirmala A Iyer, Rachel Lazarus, Kelley Lee, Hsing-Hsi Li, Hua-Peng Liaw, Brian Melton, Scott Miller, Reeham Motaher, Alexandra Novak, Omotara Ogundeyi, Alyson Petruncio, Jacquelyn Price, Sophia Protopapas, Susana Tae, Jennifer Taylor, Rebecca Vorimo, Brianna Yarbrough, Kevin Xiankun Zeng, Christopher T Zugates, Heather Dionne, Claire Angstadt, Kelly Ashley, Amanda Cavallaro, Tam Dang, Guillermo A Gonzalez III, Karen L Hibbard, Cuizhen Huang, Jui-Chun Kao, Todd Laverty, Monti Mercer, Brenda Perez, Scarlett Rose Pitts, Danielle Ruiz, Viruthika Vallanadu, Grace Zhiyu Zheng, Cristian Goina, Hideo Otsuna, Konrad Rokicki, Robert R Svirskas, Han SJ Cheong, Michael-John Dolan, Erica Ehrhardt, Kai Feng, Basel EI Galfi, Jens Goldammer, Stephen J Huston, Nan Hu, Masayoshi Ito, Claire McKellar, Ryo Minegishi, Shigehiro Namiki, Aljoscha Nern, Catherine E Schretter, Gabriella R Sterne, Lalanti Venkatasubramanian, Kaiyu Wang, Tanya Wolff, Ming Wu, Reed George, Oz Malkesman, Yoshinori Aso, Gwyneth M Card, Barry J Dickson, Wyatt Korff, Kei Ito, James W Truman, Marta Zlatic, Gerald M Rubin, FlyLight Project Team

Get full text

Perceptions of science, science communication, and climate change attitudes in 68 countries – the TISP dataset by Niels G. Mede, Viktoria Cologna, Sebastian Berger, John Besley, Cameron Brick, Marina Joubert, Edward W. Maibach, Sabina Mihelj, Naomi Oreskes, Mike S. Schäfer, Sander van der Linden, Nor Izzatina Abdul Aziz, Suleiman Abdulsalam, Nurulaini Abu Shamsi, Balazs Aczel, Indro Adinugroho, Eleonora Alabrese, Alaa Aldoh, Mark Alfano, Innocent Mbulli Ali, Mohammed Alsobay, Marlene Altenmüller, R. Michael Alvarez, Richard Amoako, Tabitha Amollo, Patrick Ansah, Denisa Apriliawati, Flavio Azevedo, Ani Bajrami, Ronita Bardhan, Keagile Bati, Eri Bertsou, Cornelia Betsch, Apurav Yash Bhatiya, Rahul Bhui, Olga Białobrzeska, Michał Bilewicz, Ayoub Bouguettaya, Katherine Breeden, Amélie Bret, Ondrej Buchel, Pablo Cabrera-Álvarez, Federica Cagnoli, André Calero Valdez, Timothy Callaghan, Rizza Kaye Cases, Sami Çoksan, Gabriela Czarnek, Steven De Peuter, Ramit Debnath, Sylvain Delouvée, Lucia Di Stefano, Celia Díaz-Catalán, Kimberly C. Doell, Simone Dohle, Karen M. Douglas, Charlotte Dries, Dmitrii Dubrov, Małgorzata Dzimińska, Ullrich K. H. Ecker, Christian T. Elbaek, Mahmoud Elsherif, Benjamin Enke, Tom W. Etienne, Matthew Facciani, Antoinette Fage-Butler, Md. Zaki Faisal, Xiaoli Fan, Christina Farhart, Christoph Feldhaus, Marinus Ferreira, Stefan Feuerriegel, Helen Fischer, Jana Freundt, Malte Friese, Simon Fuglsang, Albina Gallyamova, Patricia Garrido-Vásquez, Mauricio E. Garrido Vásquez, Winfred Gatua, Oliver Genschow, Omid Ghasemi, Theofilos Gkinopoulos, Jamie L. Gloor, Ellen Goddard, Mario Gollwitzer, Claudia González-Brambila, Hazel Gordon, Dmitry Grigoryev, Gina M. Grimshaw, Lars Guenther, Håvard Haarstad, Dana Harari, Lelia N. Hawkins, Przemysław Hensel, Alma Cristal Hernández-Mondragón, Atar Herziger, Guanxiong Huang, Markus Huff, Mairéad Hurley, Nygmet Ibadildin, Maho Ishibashi, Mohammad Tarikul Islam, Younes Jeddi, Tao Jin, Charlotte A. Jones, Sebastian Jungkunz, Dominika Jurgiel, Zhangir Kabdulkair, Jo-Ju Kao, Sarah Kavassalis, John R. Kerr, Mariana Kitsa, Tereza Klabíková Rábová, Olivier Klein, Hoyoun Koh, Aki Koivula, Lilian Kojan, Elizaveta Komyaginskaya, Laura König, Lina Koppel, Kochav Koren Nobre Cavalcante, Alexandra Kosachenko, John Kotcher, Laura S. Kranz, Pradeep Krishnan, Silje Kristiansen, André Krouwel, Toon Kuppens, Eleni A. Kyza, Claus Lamm, Anthony Lantian, Aleksandra Lazić, Oscar Lecuona, Jean-Baptiste Légal, Zoe Leviston, Neil Levy, Amanda M. Lindkvist, Grégoire Lits, Andreas Löschel, Alberto López-Ortega, Carlos Lopez-Villavicencio, Nigel Mantou Lou, Chloe H. Lucas, Kristin Lunz-Trujillo, Mathew D. Marques, Sabrina J. Mayer, Ryan McKay, Hugo Mercier, Julia Metag, Taciano L. Milfont, Joanne M. Miller, Panagiotis Mitkidis, Fredy Monge-Rodríguez, Matt Motta, Iryna Mudra, Zarja Muršič, Jennifer Namutebi, Eryn J. Newman, Jonas P. Nitschke, Ntui-Njock Vincent Ntui, Daniel Nwogwugwu, Thomas Ostermann, Tobias Otterbring, Jaime Palmer-Hague, Myrto Pantazi, Philip Pärnamets, Paolo Parra Saiani, Mariola Paruzel-Czachura, Michal Parzuchowski, Yuri G. Pavlov, Adam R. Pearson, Myron A. Penner, Charlotte R. Pennington, Katerina Petkanopoulou, Marija M. Petrović, Jan Pfänder, Dinara Pisareva, Adam Ploszaj, Karolína Poliaková, Ekaterina Pronizius, Katarzyna Pypno-Blajda, Diwa Malaya A. Quiñones, Pekka Räsänen, Adrian Rauchfleisch, Felix G. Rebitschek, Cintia Refojo Seronero, Gabriel Rêgo, James P. Reynolds, Joseph Roche, Simone Rödder, Jan Philipp Röer, Robert M. Ross, Isabelle Ruin, Osvaldo Santos, Ricardo R. Santos, Philipp Schmid, Stefan Schulreich, Bermond Scoggins, Amena Sharaf, Justin Sheria Nfundiko, Emily Shuckburgh, Johan Six, Nevin Solak, Leonhard Späth, Bram Spruyt, Olivier Standaert, Samantha K. Stanley, Gert Storms, Noel Strahm, Stylianos Syropoulos, Barnabas Szaszi, Ewa Szumowska, Mikihito Tanaka, Claudia Teran-Escobar, Boryana Todorova, Abdoul Kafid Toko, Renata Tokrri, Daniel Toribio-Florez, Manos Tsakiris, Michael Tyrala, Özden Melis Uluğ, Ijeoma Chinwe Uzoma, Jochem van Noord, Christiana Varda, Steven Verheyen, Iris Vilares, Madalina Vlasceanu, Andreas von Bubnoff, Iain Walker, Izabela Warwas, Marcel Weber, Tim Weninger, Mareike Westfal, Florian Wintterlin, Adrian Dominik Wojcik, Ziqian Xia, Jinliang Xie, Ewa Zegler-Poleska, Amber Zenklusen, Rolf A. Zwaan

Get full text

Heterogeneous Chromosomal Aberrations in Intraductal Breast Lesions Adjacent to Invasive Carcinoma by Michaela Aubele, Margaret Cummings, Axel Walch, Horst Zitzelsberger, Jörg Nährig, Heinz Höfler, Martin Werner

“…There is evidence that breast cancer is a heterogeneous disease phenotypically as well as molecular biologically. So far, heterogeneity on the molecular biological level has not been investigated in potential precursor lesions, such as ductal hyperplasia (DH) and ductal carcinoma in situ (DCIS). …”
Get full text

Cultivable Anaerobic Microbiota of Infected Root Canals by Takuichi Sato, Keiko Yamaki, Naoko Ishida, Kazuhiro Hashimoto, Yasuhisa Takeuchi, Megumi Shoji, Emika Sato, Junko Matsuyama, Hidetoshi Shimauchi, Nobuhiro Takahashi

“…In the present study, profiling of the microbiota in infected root canals was performed using anaerobic culture and molecular biological techniques for bacterial identification. …”
Get full text

Clinical Characteristics of Aldosterone- and Cortisol-Coproducing Adrenal Adenoma in Primary Aldosteronism by Lu Tang, Xintao Li, Baojun Wang, Xin Ma, Hongzhao Li, Yu Gao, Liangyou Gu, Wenyuan Nie, Xu Zhang

“…This study investigated the incidence, clinical characteristics, and molecular biological features of patients with A/CPAs. We retrospectively identified 22 A/CPA patients from 555 PA patients who visited the Chinese People’s Liberation Army General Hospital between 2004 and 2015. …”
Get full text

Issues occult hepatitis B virus infection by I. A. Morozov, L. Yu. Ilchenko, N. I. Gromova, I. G. Fyedorov, I. V. Gordeychuk, A. K. Knyazhentseva, E. V. Zverkova, M. I. Mikhaylov

“…With the help of up-to-date molecular-biological and morphological methods to determine frequency of the occult form of chronic hepatitis B (CHB) among HBsAg-negative patients with chronic liver diseases (CLD) of various etiology and to present clinical and morphological characteristic.Material and methods. …”
Get full text

Laser Capture Microdissection in Dentistry by Uraiwan Chokechanachaisakul, Tomoatsu Kaneko, Takashi Okiji, Reika Kaneko, Hideaki Suda, Jacques E. Nör

“…Thus, the advance of immuno-LCM method allows us to improve the validity of molecular biological analysis and to get more accurate diagnosis in pathological field in contrast to conventional LCM. …”
Get full text

A relação entre ciência e ideologia em tempos de hegemonia financeira: a biotecnociência e o mercado de promessas by Leandro Módolo Paschoalotte

“…From the need to understand the systematic presence, in the most different media of scientific dissemination, of the figuration of the human being as being ontologically equal to other animals, mainly because of their molecular biological characteristics, such as genetic ones. …”
Get full text

Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages by Haruaki Tomioka, Yutaka Tatano, Win Win Maw, Chiaki Sano, Yuichi Kanehiro, Toshiaki Shimizu

“…In addition, this paper highlights the immunological and molecular biological characteristics of suppressor macrophages generated in hosts with mycobacterial infections, especially MAC infection.…”
Get full text

Integration of bifurcation analysis and optimal control of a molecular network by Lakshmi N Sridhar

“…Molecular biological networks are highly nonlinear systems that exhibit limit point singularities. …”
Get full text

Unveiling the impact of CD133 on cell cycle regulation in radio- and chemo-resistance of cancer stem cells by Luyao Wu, Luyao Wu, Takanori Katsube, Xiaofei Li, Bing Wang, Yi Xie

“…The current understanding of the molecular biological function of CD133 is limited, leading to ongoing debates about its role in cancer biology. …”
Get full text

Breeding of medicinal and essential oil crops in VILAR: achievements and prospects by I. N. Korotkikh, D. N. Baleev, A. I. Morozov, P. G. Mizina, N. I. Sidelnikov

“…In breeding with the use of modern molecular biological methods, related species and generic complexes of the All-Russian Research Institute of Medicinal and Aromatic Plants (VILAR) collection can be involved, where there is extensive original genetic material of medicinal, essential oil, rare and endangered species. …”
Get full text

CRISPR/Cas Enzyme Catalysis in Liquid–Liquid Phase‐Separated Systems by Yaqin Zhang, Jianai Chen, Zhina Wu, Chenfei Zhao, Rui Wang, Zhiping Li, Jiasi Wang, Di Wang

“…The study provides novel insights into the catalytic mechanisms of CRISPR/Cas systems under physiological conditions and may contribute to the development of CRISPR‐based molecular biological tools.…”
Get full text