Investigating the dual causative pathways linking immune cells and venous thromboembolism via Mendelian randomization analysis by Ning Qi, Zhuochen Lyu, Lu Huang, Yun Zhao, Wan Zhang, Xinfeng Zhou, Yang Zhang, Jiasen Cui

“…Five commonly used Mendelian randomization (MR) methods were employed, including inverse-variance weighted (IVW), MR-Egger regression, weighted median estimator (WME), and both weighted and simple models to analyze their associations. Sensitivity checks for the results included pleiotropy tests, heterogeneity tests, and leave-one-out analyses. …”
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Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment by Yeongjin Gwon, Yuanyuan Ji, Jesse D Berman, Azar M Abadi, Ronald D Leeper, Jared Rennie, Jesse E Bell

“…A Bayesian two-stage time-series modeling approach was applied to estimate the county-level and overall risk along with the 95% Credible Intervals (Cr). …”
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External beam radiation therapy versus radical prostatectomy for high-risk prostate cancer: protocol of the RECOVER study by Caroline M. van der Starre, Chris H. Bangma, Maarten J. Bijlsma, Alfons C.M. van den Bergh, Lambertus A.L.M. Kiemeney, Wietske Kievit, Kees Vos, Diederik M. Somford, Sally M. Wildeman, Katja K.H. Aben, Igle J. de Jong, Floris J. Pos, Berdine L. Heesterman

“…Descriptive statistics and mixed-effects models are used to assess differences in HRQoL and functional outcomes over time between the patients treated with radical prostatectomy versus EBRT (+ ADT). …”
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Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study by Fataneh Esmaeili, Keyvan Karimi, Samaneh Akbarpour, Mohammadreza Naderian, Shirin Djalalinia, Ozra Tabatabaei-Malazy, Ali Golestani, Nazila Rezaei

“…Multivariate logistic regression models were performed to determine the association between different obesity patterns and uncontrolled HTN, adjusting for confounders including demographic variables, lifestyle factors, and history of metabolic abnormalities. …”
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Early onset neonatal bloodstream infections in South African hospitals by Genevieve Theron, Adrie Bekker, Larisse Bolton, Andrew Whitelaw, Arnoldus Engelbrecht, Louisa Erasmus, Aaqilah Fataar, Chandre Geldenhuys, Marlize Kunneke, Dave Le Roux, Natasha O’Connell, Kessendri Reddy, Natasha Rhoda, Lloyd Tooke, Mark Wates, Thandi Wessels, Angela Dramowski

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Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study by Ibdah R, Al-Nusair M, Abuhalimeh R, Mahmoud SA, Laswi B, Rawashdeh S, Hamoudeh A, Kheirallah KA

“…Bivariate analyses and logistic regression models were used to predict independent risk factors of ACS using adjusted odds ratios (AOR) and 95% confidence intervals (CI).Results: The study included 572 young women (≤ 50-years) with a median age of 45-years, divided into an ACS group (n=154, 26.9%) and a control group with no atherosclerotic cardiovascular disease (n=418, 73.1%). …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…Second, we used the estimated dairy consumption in linear regression models on general cognition, assessed by the Mini-Mental State Examination (MMSE) and the Mental Alternation Test, executive function, verbal fluency, verbal learning, and memory. …”
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Health Risk of Ingested Heavy Metals in Fluidized Canned Milks: Are We Drinking Heavy Metals? by Victor Eshu Okpashi

“…Peak Milk did not contain copper (Cu). Standard models for daily consumption of different heavy metals, such as Pb in Nunu (3.7E − 03) and Cowbell (−1.8E − 03), were used to construct the health risk evaluations. …”
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Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis by Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa

“…All analyses were performed in R software (v.4.2.2) using random effects models. Heterogeneity was assessed using I2 test. …”
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Pragmatic performance, its relationship with symptom severity, and early clinical predictors of pragmatics in 5 ~ 6-year-old children with autism spectrum disorder by Lu Qian, Ning Ding, Hui Fang, Ting Xiao, Bei Sun, HuiYun Gao, XiaoYan Ke

“…Third, hierarchical multiple regression analyses and machine learning techniques indicated that the proportions of SJE during parent‒child interactions, as well as the degree of social symptoms and structural language impairments, were significant contributors to pragmatic development for the ASD group in the prediction models. Conclusion In summary, our findings suggest that pragmatic language difficulties are present in children with ASD as early as preschool age. …”
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Examining differences in exposure to digital marketing of unhealthy foods reported by Canadian children and adolescents in two policy environments by Laura Vergeer, Carolina Soto, Mariangela Bagnato, Elise Pauzé, Ashley Amson, Tim Ramsay, Dana Lee Olstad, Vivian Welch, Monique Potvin Kent

“…Logistic regression and proportional odds models examined differences in exposure by province and age group, adjusting for sociodemographic characteristics and digital device usage. …”
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Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Finally, candidate genes were validated in ferroptosis models using reverse transcription quantitative PCR (RT-qPCR) and immunofluorescence methods.Results: Bulk RNA-seq analysis identified SLC11A1, an inflammatory gene associated with AD. …”
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Risk of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Randomized Clinical Trials: A Systematic Review and Meta-Analysis by Abdullah Reda, Alireza Hasanzadeh, Sherief Ghozy, Hossein Sanjari Moghaddam, Tanin Adl Parvar, Mohsen Motevaselian, Ramanathan Kadirvel, David F. Kallmes, Alejandro Rabinstein

“…Methods: Randomized controlled trials were included, following a comprehensive search of different databases from inception to 1 March 2024. Random-effect models in a meta-analysis were employed to obtain the pooled risk ratios (RRs) and their corresponding 95% confidence intervals (95% CI) for sICH with MT, and were then compared to other reperfusion treatment regimens, including best medical treatment and intravenous thrombolysis (IVT). …”
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Association of social frailty, sarcopenia, and oral frailty with depressive symptoms in Chinese older adults: a cross-sectional study by Yuanhao Sun, Huan Liu, Xiangdong Li, Lin Zhang, Wenwen Xu, Hairong liu, Ting Yuan

“…A chi-square test was performed to evaluate the differences between categorical variables, spearman correlation analysis was used to find the correlation between depressive symptoms and factors. Four regression models were set up to evaluate the effect of factors on depressive symptoms and select the appropriate adjustment variables. …”
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Il luogo e il senso: creazione e significazione degli spazi nel mondo globale by Gambardella, Fabiana, Amodio, Paolo

“…The “Sapiens 2.0” continues to construct his world as a place of signification and habitability, modelling his own “surroundings” in a way that is once again unprecedented, due to the transformations that he produces and which, in a circular and recursive process, continue to renew his features As plastic, versatile and changing entities, we exist in a global world, we easily move between semantically relevant places – home, neighbourhood, square, café – and the so-called “non-places”, spaces of transit, from airports and shopping malls to the web, which has now became the sapiens’ second home, the home within the home, or rather the ubiquitous home, in which we spend most of our time. …”
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Quality of life among residents of informal urban settlements during the COVID-19 pandemic in Salvador, Brazil by Albert I Ko, Federico Costa, Hammed Mogaji, Nivison Nery, Hernan D Argibay, Jaqueline S Cruz, Ianei O Carneiro, Ricardo Lustosa, Mike Begon, Hussein Khalil

“…We describe the HRQOL of residents, explored participants’ perception about the pandemic, and the relationship between sociodemographic, economic and employment data on physical and mental health scores using both χ2 statistics and separate mixed-effects regression models.Results Most participants were female (58.9%), aged 18–45 years (45%), with nearly half (49.7%) employed before pandemic, of whom 38.8% lost jobs during the pandemic. …”
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Sedentarismo e inactividad física según sexo, edad y nivel socioeconómico en el País Vasco. Estudio transversal by Marta Ijalba Martínez, Antonio Moreno Llamas, Unai Martín Roncero

“…Crude prevalences of sedentarism and physical inactivity, overall and by age group, were calculated, as well as the existence of a socioeconomic pattern was assessed through robust Poisson regression models. Results: The overall prevalence of sedentarism was around 32% in sexes, reaching 60% in the age group older than 85 years and 45% in young people aged 18 to 29 years. …”
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The protein structurome of Orthornavirae and its dark matter by Pascal Mutz, Antonio Pedro Camargo, Harutyun Sahakyan, Uri Neri, Anamarija Butkovic, Yuri I. Wolf, Mart Krupovic, Valerian V. Dolja, Eugene V. Koonin

“…We used protein structure modeling and similarity searches to illuminate the remaining dark matter in hundreds of thousands of orthornavirus genomes. …”
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Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials by Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu

“…Data were pooled using random-effects models. Results Eleven randomized controlled trials were finally included. …”
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