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In vitro stimulation of lymphocytes by mycoplasma synoviae derived mitogen
Published 1997-12-01Subjects: Get full text
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Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling
Published 2009-04-01“…We demonstrate that GAB1 behaves as a non‐linear amplifier of mitogenic responses and insulin endows EGF signaling with robustness to GAB1 suppression. …”
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Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer
Published 2021-08-01“…We defined patient‐overarching colorectal cancer cell clusters characterized by differential activities of oncogenic signaling pathways such as mitogen‐activated protein kinase and oncogenic traits such as replication stress. …”
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Probenecid Inhibits NLRP3 Inflammasome Activity and Mitogen-Activated Protein Kinases (MAPKs)
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Tomato mitogen-activated protein kinase: mechanisms of adaptation in response to biotic and abiotic stresses
Published 2025-02-01Subjects: “…mitogen-activated protein kinases…”
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Inhibitors of Mitogen-Activated Protein Kinases Downregulate COX-2 Expression in Human Chondrocytes
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LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy
Published 2021-11-01“…Abstract In the course of our studies aiming to discover vascular bed‐specific endothelial cell (EC) mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (BCE), although LIF has been mainly characterized as an EC growth inhibitor and an anti‐angiogenic molecule. …”
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Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses
Published 2014-01-01“…Inflammation is a natural host defensive process that is largely regulated by macrophages during the innate immune response. Mitogen-activated protein kinases (MAPKs) are proline-directed serine and threonine protein kinases that regulate many physiological and pathophysiological cell responses. p38 MAPKs are key MAPKs involved in the production of inflammatory mediators, including tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2). p38 MAPK signaling plays an essential role in regulating cellular processes, especially inflammation. …”
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Unlocking the components of mitogen-activated protein kinase pathway in Glycine max activated during herbivory
Published 2025-06-01“…Mitogen-activated protein kinases (MPKs) substantially govern plant immune reactions. …”
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Influence on mitogen-activated protein kinases as a new direction of connective tissue growth regulation
Published 2018-01-01Subjects: “…mitogen-activated protein kinase…”
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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics.
Published 2025-01-01“…Mitogen-activated protein kinase 1 (MAPK1) is a serine/threonine kinase that plays a crucial role in the MAP kinase signaling transduction pathway. …”
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Mitogen-Activated Protein Kinase Kinase Kinase 1 Overexpression Disrupts Development of the Ocular Surface Epithelium
Published 2025-06-01“…Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) is a key signaling molecule essential for eyelid closure during embryogenesis. …”
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Polymorphism of Mitogen-activated protein kinase 12 (MAPK12) gene in Vechur and Kasargod cattle of Kerala
Published 2025-06-01“…The mitogen-activated protein kinase 12 (MAPK12) gene, located on chromosome 5 of the cattle genome and consists of 12 exons. …”
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p38α Mitogen-Activated Protein Kinase—An Emerging Drug Target for the Treatment of Alzheimer’s Disease
Published 2024-09-01Subjects: Get full text
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EFFECTS OF STATINS AND OTHER BIOLOGICAL PREPARATIONS UPON ACTIVATION OF MITOGEN-ACTIVATED PROTEIN KINASES IN PATIENTS WITH RHEUMATOID ARTHRITIS
Published 2014-07-01Subjects: Get full text
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Expression and effect of P38 mitogen-activated protein kinase and transforming growth factor-β in gastric cancer
Published 2025-01-01Subjects: “…p38 mitogen-activated protein kinase…”
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Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathway.
Published 2014-01-01“…Furthermore, lidocaine and bupivacaine attenuated extracellular signal-regulated kinase 1/2 (ERK1/2) activity and induced activation of p38 mitogen-activated protein kinase (MAPK) and c-jun N-terminal kinase. …”
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p38 mitogen-activated protein kinase drives senescence in CD4+ T lymphocytes and increases their pathological potential
Published 2025-07-01“…It is well known that the activation of p38 mitogen-activated protein kinase (p38 MAPK) orchestrates senescence in CD8+ T lymphocytes. …”
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