Showing 1 - 20 results of 960 for search '"mitogen"', query time: 0.08s Refine Results
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    Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling by Nikolay Borisov, Edita Aksamitiene, Anatoly Kiyatkin, Stefan Legewie, Jan Berkhout, Thomas Maiwald, Nikolai P Kaimachnikov, Jens Timmer, Jan B Hoek, Boris N Kholodenko

    Published 2009-04-01
    “…We demonstrate that GAB1 behaves as a non‐linear amplifier of mitogenic responses and insulin endows EGF signaling with robustness to GAB1 suppression. …”
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    Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer by Florian Uhlitz, Philip Bischoff, Stefan Peidli, Anja Sieber, Alexandra Trinks, Mareen Lüthen, Benedikt Obermayer, Eric Blanc, Yana Ruchiy, Thomas Sell, Soulafa Mamlouk, Roberto Arsie, Tzu‐Ting Wei, Kathleen Klotz‐Noack, Roland F Schwarz, Birgit Sawitzki, Carsten Kamphues, Dieter Beule, Markus Landthaler, Christine Sers, David Horst, Nils Blüthgen, Markus Morkel

    Published 2021-08-01
    “…We defined patient‐overarching colorectal cancer cell clusters characterized by differential activities of oncogenic signaling pathways such as mitogen‐activated protein kinase and oncogenic traits such as replication stress. …”
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    LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy by Pin Li, Qin Li, Nilima Biswas, Hong Xin, Tanja Diemer, Lixian Liu, Lorena Perez Gutierrez, Giovanni Paternostro, Carlo Piermarocchi, Sergii Domanskyi, Ruikang K Wang, Napoleone Ferrara

    Published 2021-11-01
    “…Abstract In the course of our studies aiming to discover vascular bed‐specific endothelial cell (EC) mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (BCE), although LIF has been mainly characterized as an EC growth inhibitor and an anti‐angiogenic molecule. …”
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    Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses by Yanyan Yang, Seung Cheol Kim, Tao Yu, Young-Su Yi, Man Hee Rhee, Gi-Ho Sung, Byong Chul Yoo, Jae Youl Cho

    Published 2014-01-01
    “…Inflammation is a natural host defensive process that is largely regulated by macrophages during the innate immune response. Mitogen-activated protein kinases (MAPKs) are proline-directed serine and threonine protein kinases that regulate many physiological and pathophysiological cell responses. p38 MAPKs are key MAPKs involved in the production of inflammatory mediators, including tumor necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2). p38 MAPK signaling plays an essential role in regulating cellular processes, especially inflammation. …”
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    Unlocking the components of mitogen-activated protein kinase pathway in Glycine max activated during herbivory by Megha Kumari, Indrakant K. Singh, Kshama Sharma, Archana Singh

    Published 2025-06-01
    “…Mitogen-activated protein kinases (MPKs) substantially govern plant immune reactions. …”
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    Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics. by Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md Imtaiyaz Hassan

    Published 2025-01-01
    “…Mitogen-activated protein kinase 1 (MAPK1) is a serine/threonine kinase that plays a crucial role in the MAP kinase signaling transduction pathway. …”
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    Mitogen-Activated Protein Kinase Kinase Kinase 1 Overexpression Disrupts Development of the Ocular Surface Epithelium by Maureen Mongan, Bo Xiao, Antonius Christianto, Yueh-Chiang Hu, Ying Xia

    Published 2025-06-01
    “…Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) is a key signaling molecule essential for eyelid closure during embryogenesis. …”
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    Polymorphism of Mitogen-activated protein kinase 12 (MAPK12) gene in Vechur and Kasargod cattle of Kerala by T.X. Seena, Elizabeth Kurian, F.A. Lali, P.M. Rojan, K.A. Bindu, Aziz Zarina, K. George Sherin

    Published 2025-06-01
    “…The mitogen-activated protein kinase 12 (MAPK12) gene, located on chromosome 5 of the cattle genome and consists of 12 exons. …”
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    Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathway. by Yuan-Ching Chang, Yi-Chiung Hsu, Chien-Liang Liu, Shih-Yuan Huang, Meng-Chun Hu, Shih-Ping Cheng

    Published 2014-01-01
    “…Furthermore, lidocaine and bupivacaine attenuated extracellular signal-regulated kinase 1/2 (ERK1/2) activity and induced activation of p38 mitogen-activated protein kinase (MAPK) and c-jun N-terminal kinase. …”
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