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The context signals of mitochondrial miRNAs (mitomiRs) of mammals
Published 2023-01-01Subjects: Get full text
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Insights into structure, codon usage, repeats, and RNA editing of the complete mitochondrial genome of Perilla frutescens (Lamiaceae)
Published 2024-06-01Subjects: Get full text
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Effect of potato glycoside alkaloids on mitochondria energy metabolism of Fusarium solani, the root rot pathogen of Lycium barbarum
Published 2025-01-01Subjects: Get full text
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Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids
Published 2025-02-01Subjects: Get full text
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Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction
Published 2025-01-01Subjects: Get full text
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The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice
Published 2025-01-01Subjects: Get full text
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Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy
Published 2020-01-01“…Mitochondria are known treatment target of SNHL, but mitochondrion mechanism and pathology in SGNs are not valued. …”
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Derivation and Characterization of Isogenic <i>OPA1</i> Mutant and Control Human Pluripotent Stem Cell Lines
Published 2025-01-01“…Within the mitochondrion, proteolytically processed OPA1 proteins form complexes to maintain membrane integrity and the respiratory chain complexity. …”
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Mitochondrial Stress Signaling Promotes Cellular Adaptations
Published 2014-01-01“…This involves communication of stress to the cell and successful induction of quality control responses, which include mitophagy, unfolded protein response, upregulation of antioxidant and DNA repair enzymes, morphological changes, and if all else fails apoptosis. The mitochondrion is an inherently stressful environment and we speculate that dysregulation of stress signaling or an inability to switch on these adaptations during times of mitochondrial stress may underpin mitochondrial dysfunction and hence amount to pathological states over time.…”
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Modes and mechanisms for the inheritance of mitochondria and plastids in pathogenic protists.
Published 2025-01-01“…Almost all protists possess mitochondria or mitochondrion-related organelles, and many contain plastids. …”
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Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation: Implications in Cancer and Neurodegeneration
Published 2012-01-01“…In particular, emphasis will be given to the possible, but still neglected implication of denitrosylation reactions in the modulation of mitochondrial SNOs and how they can affect mitochondrion-related cellular process, such as oxidative phosphorylation, mitochondrial dynamics, and mitophagy.…”
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Role of mitochondrial and lysosomal dysfunction in acute pancreatitis pathogenesis
Published 2016-08-01“…Therefore new studies aimed for therapeutic impact on mitochondrions and lysosomes are required. Key words: acute pancreatitis, dysfunction of organellas, mitochondrion, lysosome, apoptosis, necrosis, autophagy.…”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease
Published 2025-01-01“…Various fluorescent probes and energy detector are used to detect mitochondrial apoptosis, ROS, and respiration of mitochondrion. Results Through the single-cell atlas of DKD mouse kidneys, it was found that losartan treatment significantly increased the percentage of PT cells. …”
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Proteomic Analysis Reveals Growth Inhibition of Coriolus versicolor by Methanol Extracts of Cinnamomum camphora Xylem
Published 2021-01-01“…Cellular localization was performed to identify these differential proteins, and biological process and functional analysis found that 9 of these proteins were in the cytoplasm, 6 were intracellular, and 5 were in the mitochondrion. A total of 18.8% were mapped to small-molecule metabolic processes, 12.5% to cellular amino acid metabolic processes, and 10.9% to cellular nitrogen compound metabolic processes. …”
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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice
Published 2015-01-01“…Multiple extracellular (pH, heat, oxidants, and detergents) or intracellular (DNA damage and Ca2+ overload) stress conditions trigger various types of the nuclear, endoplasmic reticulum (ER), cytoplasmatic, and mitochondrion-centered signaling events that allow cells to preserve the DNA integrity, protein folding, energetic, ionic and redox homeostasis, thus escaping from injury. …”
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Research Progress of ROS-Mitochondrial Pathway on Cardiovascular Protection of Tea Polyphenols
Published 2025-02-01“…Reactive oxygen species (ROS) imbalance and mitochondrial dysfunction played critical roles in the pathogenesis of cardiovascular diseases which are the leading cause of death worldwide. Mitochondrion is the main ROS production, which is also the vulnerable target for ROS attack. …”
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Mitochondrial DNA Structure in <i>Trypanosoma cruzi</i>
Published 2025-01-01“…Kinetoplastids display a single, large mitochondrion per cell, with their mitochondrial DNA referred to as the kinetoplast. …”
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Construction and Evaluation of a Subcutaneous Splenic Injection Port for Serial Intraportal Vein Cell Delivery in Murine Disease Models
Published 2019-01-01“…Fluorescent-labeled cell tracking and antihuman mitochondrion immunohistochemistry studies demonstrated that the cells localized predominantly in small distal portal branches. …”
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Differentially expressed whey proteins of donkey and bovine colostrum revealed with a label-free proteomics approach
Published 2023-07-01“…Gene Ontology analysis revealed that these DEWPs were mainly related to cellular components, such as extracellular exosome, plasma membrane, and mitochondrion; biological processes, such as oxidation-reduction process, cell-cell adhesion, and small guanosine triphosphate (GTP) ase-mediated signal transduction; and molecular functions, such as GTP binding, GTPase activity, and soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor activity. …”
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