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Bi-allelic variants in WDR47 cause a complex neurodevelopmental syndrome
Published 2024-11-01Subjects: Get full text
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22
Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells
Published 2024-12-01Subjects: Get full text
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23
Fish scale-inspired biomimetic nanocoatings on magnesium implants for vascularized bone regeneration in infected bone defects
Published 2025-01-01Subjects: Get full text
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24
Correlation between Cellular Autophagy and Color Changes in Qinchuan Cattle Meat during Postmortem Aging
Published 2025-02-01Subjects: “…cellular autophagy; mitochondrial function; beclin1; microtubule-associated protein light chain 3-ii; meat color…”
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25
Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells
Published 2025-01-01Subjects: Get full text
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26
Maytansinoids in cancer therapy: advancements in antibody–drug conjugates and nanotechnology-enhanced drug delivery systems
Published 2025-01-01Subjects: Get full text
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27
Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury
Published 2023-01-01“…The growth and extension of neuronal axons is a dynamic biological process mediated by the cytoskeleton, and microtubule plays an important role in axonal growth. …”
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28
Molecular characterization of the TUBG1 meshwork's influence on Cytoskeletal organization
Published 2025-01-01“…The γ-tubulin (TUBG) meshwork is a central regulator of cellular architecture, orchestrating processes such as microtubule nucleation, mitochondrial organization, and genomic integrity. …”
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29
Disomic chromosome 3R(3B) substitution causes a complex of meiotic abnormalities in bread wheat <i>Triticum aestivum</i> L.
Published 2024-07-01“…The results revealed a set of abnormalities in the microtubule dynamics and chromosome behavior in both first and second divisions. …”
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30
The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans.
Published 2025-01-01“…During chromosome segregation, the spindle assembly checkpoint (SAC) detects errors in kinetochore-microtubule attachments. Timely activation and maintenance of the SAC until defects are corrected is essential for genome stability. …”
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31
Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain
Published 2014-01-01“…And Aβ40 and Aβ42 were found overproduced and the microtubule-associated protein tau was hyperphosphorylated in the hippocampus. …”
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32
IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells
Published 2012-01-01“…IQGAPs perform their myriad functions through association with a large number of proteins including filamentous actin (F-actin), GTPases, calcium-binding proteins, microtubule binding proteins, kinases, and receptors. …”
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33
Polycystic Diseases in Visceral Organs
Published 2011-01-01“…Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. …”
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34
The Golgi in Cell Migration: Regulation by Signal Transduction and Its Implications for Cancer Cell Metastasis
Published 2012-01-01“…In this paper we will give an overview on how polarized secretion and microtubule nucleation at the Golgi regulate directional cell migration. …”
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35
Gas-phase fractionation DDA promotes in-depth DIA phosphoproteome analysis
Published 2025-01-01“…DEPsites in indirect ALI were enriched in proteins related to microtubule polymerization, positive regulation of microtubule polymerization and fibroblast migration. …”
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36
Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response
Published 2023-08-01“…The shape of the cell is largely dependent on cytoskeletal proteins, especially, microtubules. As a microtubule-targetting drug, vinblastine (VBL) has been used in chemotherapy. …”
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37
Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology
Published 2015-01-01“…This review summarized the numerous interdependent mechanisms including excessive dopamine, ubiquitin-proteasome system dysfunction, protein nitration, endoplasmic reticulum stress, p53 expression, inflammatory molecular, D3 receptor, microtubule deacetylation, and HIV-1 Tat protein that have been demonstrated to contribute to this damage. …”
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38
Cell Cycle Dynamics of the Nuclear Envelope
Published 2003-01-01“…During mitosis, the NE is disassembled upon phosphorylation of its core components, and the NE is torn apart by a dynein-driven microtubule-dependent mechanism. Nuclear reassembly after sister chromatid separation requires a timely coordinated and dephosphorylation-dependent association of lamin-binding proteins and lamins with chromosomal proteins and targeting of membranes to specific sites on chromosomes. …”
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(<i>E</i>)-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1<i>H</i>-1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Anti...
Published 2025-01-01“…These compounds were designed as hybrids of the microtubule-targeting chalcones, indanones, and the aromatase inhibitor letrozole. …”
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40
Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR-γ Functional Module of Autophagy in Rheumatoid Arthritis
Published 2019-01-01“…For the first time, we report a defective functional module of autophagy comprising the Vitamin D receptor (VDR), PPAR-γ, microtubule-associated protein 1 light-chain 3 (LC3), and p62 which appears in RA synovial fibroblasts. …”
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