Dual targeting PD-L1 and 4-1BB to overcome dendritic cell-mediated lenalidomide resistance in follicular lymphoma by Zhong Zheng, Jian-Biao Wang, Rui Sun, Nan Wang, Xiang-Qin Weng, Tian-Yuan Xu, Di Fu, Yan Feng, Peng-Peng Xu, Shu Cheng, Li Wang, Yan Zhao, Bin Qu, Chuan-Xin Huang, Wei-Li Zhao

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MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research by Zeinab G. Khalil, Thulasi Sritharan, Angela A. Salim, Robert J. Capon

“…By employing a variety of media compositions and cultivations, MATRIX enhances the understanding of microbial metabolic pathways and interactions. This protocol provides a robust platform for natural product discovery, microbial ecology studies, and drug development, showcasing its potential to uncover new natural products and other valuable bioactives. …”
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Propionate metabolism in Desulfurella acetivorans by Eugenio Pettinato, Thomas M. Steiner, Eric A. Cassens, Thomas Geisberger, Christian Seitz, Simone König, Wolfgang Eisenreich, Ivan A. Berg

“…These results highlight the uncertainty of genomic predictions in the analysis of microbial metabolic pathways and the need for their experimental confirmation.…”
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Metagenomics approaches for studying the human microbiome by Biniam Moges, Degisew Yinur Mengistu

“…Hence, metagenomics analysis is a powerful advanced technology for comprehensively studying human microbial composition and diversity, exploring novel and antibiotic resistance genes, microbial metabolic pathways, functional dysbiosis, and co-evolution of the microbiome with the host. …”
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Response Analysis of Microbial Community Structures and Functions Under Water and Sediment Changes in the Middle and Lower Yellow River by Ji Wu, Quan Hong, Jin Zhang, Chen Xie, Yang Liu, Dandan Li, Hao Liu, Ziwu Fan

“…The WSR programme broke down nutrients that had been adsorbed on the sediments, which diminished microbial metabolic activity and impaired the water bodies’ capacity to purify themselves. …”
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Denitrification research based on green electron supply and cell metabolism regulation by LIU Chao, FAN Xinyun, ZHANG Xuemeng, CHEN Chuang, ZHU Mengru, CHEN Yinguang*

“…Firstly, the types of photosensitizers, the dominant functional microorganisms, the photosensitizer-microbe complex in the process of photoelectron-driven denitrification, and the application status of phototrophic denitrification are systematically reviewed. Then, the microbial metabolic pathway of denitrification using methane, propane, and other short-chain alkanes as carbon sources is described, the performance of kitchen waste and other organic wastes as carbon source is introduced, and the formation mechanism and utilization characteristics of microbial carbon sources are also analyzed. …”
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Dietary Fiber with Functional Properties Counteracts the Thwarting Effects of Copper Nanoparticles on the Microbial Enzymatic Activity and Short-Chain Fatty Acid Production in the... by Jerzy Juśkiewicz, Bartosz Fotschki, Anna Stępniowska, Ewelina Cholewińska, Dorota Napiórkowska, Aleksandra Marzec, Łucja Brzuzan, Joanna Fotschki, Ewa Żary-Sikorska, Katarzyna Ognik

“…The present study aimed to scrutinize the hypothesis that the dietary addition of fiber with functional properties would prevent the thwarting effects of copper nanoparticles (Cu-NP) on fecal microbial metabolic activity. The Wistar rats were fed for 6 weeks with diets with two different contents of Cu-NP (a recommended dose of 6.5 mg/kg or doubled) and four sources of dietary fiber: control – cellulose; and experimental – pectin, inulin, and psyllium. …”
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Acidity, sugar, and alcohol contents during the fermentation of Osmanthus-flavored sweet rice wine and microbial community dynamics by Ping Tian, Jiaqiong Wan, Tuo Yin, Li Liu, Hongbing Ren, Hanbing Cai, Xiaozhen Liu, Hanyao Zhang

“…In this study, the dynamic changes in sugar level, acidity, alcohol content, microbial community composition, and microbial metabolic pathways during traditional fermentation of OFSRW at four-time points—0 h (AG0), 24 h (AG24), 36 h (AG36), and 43 h (AG43)—were analyzed via direct titration, total acid assays, alcoholometry, and high-throughput macrogenomic techniques. …”
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Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…Serpentinization, the reaction of water with ultramafic rock, produces reduced, hyperalkaline, and H2-rich fluids that support a variety of hydrogenotrophic microbial metabolisms. Previous work indicates the occurrence of methanogenesis in fluids from the actively serpentinizing Samail Ophiolite in the Sultanate of Oman. …”
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Association between airway microbiota and systemic inflammation markers in non-small cell lung cancer patients by DanHui Huang, QianNan Ren, LingYan Xie, YueHua Chen, Cui Li, XiaoFang Su, LiShan Lin, LaiYu Liu, Haijin Zhao, Tingyue Luo, JianHua Wu, Shaoxi Cai, Hangming Dong

“…Patients with relative high inflammation status were associated with alteration of specific airway genera and microbial metabolic function.…”
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The Effect of Cysteine on the Removal of Cadmium in Paddy Soil by Combination with Bioremediation and the Response of the Soil Microbial Community by Emmanuel Konadu Sarkodie, Kewei Li, Ziwen Guo, Jiejie Yang, Yan Deng, Jiaxin Shi, Yulong Peng, Yuli Jiang, Huidan Jiang, Hongwei Liu, Yili Liang, Huaqun Yin, Xueduan Liu, Luhua Jiang

“…The relative abundances of <i>Alicyclobacillus</i>, <i>Metallibacterium</i>, and <i>Bacillus</i> were increased in the paddy soils. The microbial metabolic functions, such as replication and repair and amino acid metabolism, were also increased after treatment, which benefitted the microbial survival and adaptation to the environment. …”
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Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism by Yimin Zhuang, Duo Gao, Wen Jiang, Yiming Xu, Guanglei Liu, Guobin Hou, Tianyu Chen, Shangru Li, Siyuan Zhang, Shuai Liu, Jingjun Wang, Jianxin Xiao, Mengmeng Li, Wei Wang, Shengli Li, Zhijun Cao

“…In cluster2, Bifidobacterium members were the dominant contributors to microbial metabolic functions with a higher abundance. Furthermore, pathways involved in carbohydrate degradation, glycolysis, and biosynthesis of propionate and proteins were active, while methane production was inhibited. …”
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Effects of Mixing Tree Species on Soil Enzyme Activity and Carbon-Use Efficiency in Eroded Masson Pine Forest by WANG Man, JIANG Yongmeng, ZHANG Shiliang, ZHANG Jinxiu, ZHENG Linmin, ZENG Zhiwei, LYU Maokui, XIE Jinsheng

“…[Objective] Soil microbial metabolic efficiency profoundly affects soil nutrient cycling and soil carbon sequestration in the recovery process of eroded and degraded areas. …”
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