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Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray
Published 2022-07-01Subjects: Get full text
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Investigation of local corrosion behavior and mechanism for TA2/HAl77-2/316L SS coupling systems under seawater liquid film
Published 2025-02-01Subjects: Get full text
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Toward spatial glycomics and glycoproteomics: Innovations and applications
Published 2025-01-01Subjects: Get full text
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Comprehensive analysis of differential mRNA and circRNA profiles in primary and metastatic pancreatic neuroendocrine tumors
Published 2025-03-01Subjects: Get full text
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Generalizability of machine learning models for diabetes detection a study with nordic islet transplant and PIMA datasets
Published 2025-02-01Subjects: Get full text
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Analysis of long noncoding gene expression and its interactions with protein-coding genes in vascular endothelial cells in keloids
Published 2025-02-01“…Conclusions Through the in-depth mining of keloid microarray data using bioinformatic methods, we speculated that VECs can affect the development and progression of keloids by epigenomic regulation via lncRNA‒mRNA interactions.…”
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Unravelling the Impact of an Additional Sex Chromosome in an Adult Female
Published 2023-04-01“…Interphase fluorescence in situ hybridisation was performed to confirm the diagnosis. Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. …”
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An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA
Published 2024-12-01“…Conventional methods for miRNA detection, such as quantitative PCR and microarray analysis, often entail intricate sample preparation and lack the requisite sensitivity to detect low-abundance miRNAs like miRNA-21. …”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma.
Published 2025-01-01“…We assessed cell proliferation, migration, and invasion capabilities through in vitro assays (including CCK-8, Edu, wound healing, and transwell assays) and quantitatively analyzed TSPAN13 expression levels in clinical glioma samples using tissue microarray immunohistochemistry. The impact of TSPAN13 on TMZ resistance in GBM cells was validated through in vitro experiments and a mouse orthotopic xenograft model. …”
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Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment.
Published 2025-01-01“…Researching the interaction between cuproptosis and allergic rhinitis will likely pave the way for future treatment of this disease.<h4>Methods</h4>A microarray dataset of AR patients and normal controls (GSE43523) were obtained from the Gene Expression Omnibus (GEO) database for differential gene analysis. …”
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LASSO–MOGAT: a multi-omics graph attention framework for cancer classification
Published 2024-08-01“…By utilizing differential expression analysis (DEG) with Linear Models for Microarray (LIMMA) and LASSO regression for feature selection and leveraging graph attention networks (GATs) to incorporate protein–protein interaction (PPI) networks, LASSO–MOGAT effectively captures intricate relationships within multi-omics data. …”
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Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid–liquid phase separation-related genes
Published 2025-02-01“…Hub genes were screened that displayed high prediction accuracy of UC patients. Both the microarray and scRNA-seq datasets showed a strong correlation with immune cell infiltration and cytokines, especially GBP1, TRIM22, SRI. …”
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Exosome-like nanovesicles derived from kale juice enhance collagen production by downregulating Smad7 in human skin fibroblasts
Published 2025-02-01“…GELNs increased type I collagen expression in NB1RGB cells significantly. Microarray analysis demonstrated that GELN-derived total RNA upregulated the expression of genes related to extracellular matrix formation, including those involved in collagen synthesis. …”
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Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing
Published 2025-02-01“…We also offer protein expression data from a tissue microarray (TMA) analysis of 90 samples (45 PMPs). Our single-cell and bulk transcriptomic profiles, along with TMA verifications, reveal the cellular diversity of PMP, highlighting the coexistence of epithelial and mesenchymal characteristics within PMP cells. …”
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Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis
Published 2025-02-01“…Methods Four independent synovial tissue microarray transcriptome sequencing datasets and one single cell sequencing dataset were downloaded from the Gene Expression Omnibus (GEO) database, and the hub gene of RA fibroblast-like synovial cells was identified by differential gene analysis, weighted gene co-expression network analysis (WGCNA) and single-cell sequencing data analysis. …”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion
Published 2024-09-01“…Meanwhile, multiple fluorescent immunohistochemical staining was used to study the distribution characteristics of TIM‐4, and through tissue microarrays, we explored its correlation with patient prognosis. …”
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MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis
Published 2025-02-01“…Abstract The detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0–6 years of age) with G-PAVMs and after the Fontan procedure without G-PAVMs. …”
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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
Published 2024-01-01“…The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis
Published 2025-02-01“…Methods TCGA public database and a tissue microarray were used to investigate the molecular characteristics of CLIP4 and its association with disease. …”
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