Primary dysmenorrhea: pathophysiology, improvement of diagnostic and treatment possibilities by T.V. Fartushok, N.V. Fartushok

“…As a result of the proposed treatment, pain disappeared completely in 70% of patients (23/34), as well as vegetative-vascular (from 18 to 2% of patients), vegetative (from 10 to 1% of patients), metabolic and endocrine disorders (from 15 to 2% female patients), disorders of the emotional and mental sphere (from 25 to 10% of patients). …”
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Metformin as an adjuvant option for systemic treatment of breast cancer by D.I. Avierin, V.F. Zavizion

“…First one is driven by its impact on the metabolic function of cells and energy deficit. Second – the method of regulating the proliferation of tumor cells involves the PIK3 branch of the regulatory cascade of biological reactions in cancer cells. …”
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Tyrosine hydroxylase of the brain and it’s regulation by glucocorticoids by E. V. Sukhareva, T. S. Kalinina, V. V. Bulygina, N. N. Dygalo

“…Early life stress events can produce long-lasting changes in neurochemistry and behaviors related to monoamine systems, with increased risks of cardiovascular, metabolic, neuroendocrine, psychiatric disorders, generalized anxiety and depression in adulthood. …”
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The burden of Alagille syndrome: uncovering the potential of emerging therapeutics – a comprehensive systematic literature review by Philip Bufler, Robin Howard, Lucia Quadrado, Guy Lacey, Jolan Terner-Rosenthal, Andrea Goldstein, Pamela Vig, Deirdre Kelly

Neurotransmitters crosstalk and regulation in the reward circuit of subjects with behavioral addiction by Zhenlei Peng, Qiyu Jia, Junxiong Mao, Xiao Luo, Anqi Huang, Hao Zheng, Shijie Jiang, Qi Ma, Qi Ma, Chuang Ma, Qizhong Yi

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Turismo en Mallorca by Macià Blázquez Salom

“…Geography can help inform this political debate on the transformation of the system of production, consumption and social relations oriented towards a necessary contraction and convergence of the metabolic flow per capita, for the improvement of human welfare and by redistributive, egalitarian and consensual methods. …”
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In vivo MRS study of long-term effects of traumatic intracranial injection of a culture medium in mice by O. B. Shevelev, O. P. Cherkasova, I. A. Razumov, E. L. Zavjalov

“…Currently, there are no data on the dynamic metabolic processes in the brain that occur after the introduction of glioblastoma cells into the brain of mice. …”
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Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration by Jan Studnička, Eva Rencová, Milan Bláha, Pavel Rozsíval, Miriam Lánská, Vladimír Bláha, Jan Němčanský, Hana Langrová

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The study of pubertal stage and age of menarche in girls in Isfahan province, Iran by Nafiseh Mozafarian, Mahin Hashemipour, Mohammad Reza Maracy, Masoumeh Pourrajab, Razieh Omidi, Roya Kelishadi

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Systematic review of the impact of non-alcoholic fatty liver disease on mortality and adverse clinical outcomes for individuals with chronic kidney disease by Paul Roderick, Julie Parkes, Theresa Hydes, Ryan Buchanan, Oliver J Kennedy, Simon Fraser

“…One reported a significant positive association for NAFLD with all-cause mortality for individuals with CKD (p<0.05) (cardiovascular-related mortality p=ns), which was lost following adjustment for metabolic risk factors; the second reported no effect in adjusted and unadjusted models. …”
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Preservation of the Photoreceptor Inner/Outer Segment Junction in Dry Age-Related Macular Degeneration Treated by Rheohemapheresis by Eva Rencová, Milan Bláha, Jan Studnička, Vladimír Bláha, Miriam Lánská, Ondřej Renc, Alexander Stepanov, Věra Kratochvílová, Hana Langrová

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Diabetes self-management education (DSME) for older persons in Western countries: A scoping review. by Pilar Camargo-Plazas, Madison Robertson, Beatriz Alvarado, Geneviève C Paré, Idevania G Costa, Lenora Duhn

“…Diabetes mellitus is a chronic metabolic health condition affecting millions globally. …”
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Pharmacogenetics: Influence of CYP2C9*2 and *3 alleles polymorphisms on Iraqi type 2 diabetic patients by Ghada S. Rasool, Asmaa A. Hussien, Suhad R. Al-Tayie, Salwa J. Al-Awadi, Hussein OM Al-Dahmoshi

“…The enzyme responsible for metabolizing of SUs is hepatic cytochrome P4502C9 (CYP2C9). …”
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The role of vitamin D in slipped capital femoral epiphysis in children and adolescents: a retrospective case-control study by Peng Ning, Shuting Lin, Huiyu Geng, Tianjing Liu

“…ObjectiveTo explore the correlation between vitamin D levels, related endocrine/metabolic factors, and the risk of slipped capital femoral epiphysis (SCFE) in children and adolescents, and to assess whether vitamin D levels are associated with SCFE severity.MethodsA retrospective case-control study was conducted from March 2014 to October 2023 in Shengjing hospital. …”
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Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study by Suyeon Park, Seong-Hyeok Bak, Hyun-Sook Kim, Kyung-Ann Lee

“…Abstract Background Obstructive sleep apnea (OSA) is linked to various health conditions, including cardiovascular diseases and metabolic disorders. Hyperuricemia and gout may be associated with OSA, but large-scale studies on this are limited. …”
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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

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Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination by Kai Zhao, Xiaofan Wu, Bo Liang, Shuang Gao, Jieyan Yang, Yan Bai, Yaru Wang, Xin Tian, Fang Wang, Xiuqing Yang

“…Our results emphasized four key biological processes—cellular response to ethylene stimulus, phenylpropanoid metabolic process, ethylene-activated signaling pathway, and monooxygenase activity—along with several relevant pathways, including plant hormone signal transduction, flavone and flavonol biosynthesis, biosynthesis of secondary metabolites, and MAPK signaling pathway, all crucial for walnut bud germination. …”
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Determinants of growth differentiation factor 15 plasma levels in outpatients with peripheral arterial disease by Emma Skau, Philippe Wagner, Jerzy Leppert, Johan Ärnlöv, Pär Hedberg

“…To better understand the pathophysiological role of GDF-15 and its link to clinical outcomes in patients with PAD, future studies should focus on the metabolic processes involved in atherosclerotic disease.…”
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Obesity-induced mesenteric PVAT remodelling is sexually dimorphic, but not driven by ovarian hormones by Lisa Ivatt, Mhairi Paul, Allende Miguelez-Crespo, Patrick W. F. Hadoke, Matthew A. Bailey, Ruth A. Morgan, Mark Nixon

“…Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vessels, plays a key role in regulating vascular tone. …”
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Glycogen Storage Disease Type Ia: A Retrospective Claims Analysis of Complications, Resource Utilization, and Cost of Care by Eliza Kruger, Justin Nedzesky, Nina Thomas, Jeffrey D. Dunn, Andrew A. Grimm

“…**Background:** Glycogen storage disease type Ia (GSDIa) is a rare inherited disorder resulting in potentially life-threatening hypoglycemia, metabolic abnormalities, and complications often requiring hospitalization. …”
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