Turismo en Mallorca by Macià Blázquez Salom

“…Geography can help inform this political debate on the transformation of the system of production, consumption and social relations oriented towards a necessary contraction and convergence of the metabolic flow per capita, for the improvement of human welfare and by redistributive, egalitarian and consensual methods. …”
Get full text

Spatial Transcriptome and Single Nucleus Transcriptome Sequencing Reveals Tetrahydroxy Stilbene Glucoside Promotes Ovarian Organoids Development Through the Vegfa‐Ephb2 Pair by Chunlan Mu, Xiaoyong Li, Jiamei Yang, Geng G. Tian, Hepeng Bai, Wenhui Lin, Linhui Wang, Ji Wu

Get full text

Biochemical characteristics, genetic variants and treatment outcomes of 55 Chinese cases with neonatal intrahepatic cholestasis caused by citrin deficiency by Juan Li, Jintao Duan, Shuli He, Ying Li, Meifen Wang, Chengjun Deng

“…In long term follow-up, 2 cases developed FTTDCD, 8 cases had special dietary habits, and 1 case died from cirrhosis.ConclusionsNICCD showed more severe impairments in liver, coagulation, and metabolic function than INC. Significantly increased AFP levels could provide reference for the differential diagnosis of NICCD. …”
Get full text

Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

Get full text

Plant cell wall and the mechanisms of resistance to pathogens by O. G. Smirnova, A. V. Kochetov

“…Dozens of proteins inside the cell wall are involved in structural and metabolic processes as well as in signal transduction and regulatory circuits (more information is available in W allProtDB database). …”
Get full text

Diabetes Management and Outcomes among Patients with Type 2 Diabetes Attending a Renal Service by Elizabeth Skalkos, Rohit Rajagopal, David Simmons

“…To assess the achievement of metabolic targets and compare the current management of renal service attenders with insulin- and noninsulin-treated T2DM. …”
Get full text

A new approach to off-gas analysis for shaken bioreactors showing high CTR and RQ accuracy by Andreas Schulte, Janik Brockmann, Nina Müller, Tibor Anderlei, Jochen Büchs

“…The accuracy of RQ measurement was +-4% for the tested range (8% filling volume, OTR and CTR: 0–56 mmol/L/h), allowing for the determination of metabolic switches and quantitative analysis of metabolites. …”
Get full text

Phase 1 study of novel anti-platelet agent to overcome pharmacogenomic limitations of clopidogrel by Anil Pareek, Nitin Chandurkar, Vivek Raut, Kumar Naidu

“…Further, %inhibition of platelet aggregation from AT-10 treatment in poor metaboliser group was significantly higher than the clopidogrel treatments in extensive metaboliser group.Overall pharmacokinetic comparison in all subjects indicates that AT-10 gives greater exposure to active Metabolite H4 than clopidogrel.Conclusion AT-10 showed better inhibition of platelet aggregation in poor metabolizers as compared to Clopidogrel. AT-10 may emerge as a potential alternative to Clopidogrel as an anti-platelet drug. …”
Get full text

Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes by Miriam Maraslioglu, Elsie Oppermann, Carolin Blattner, Roxane Weber, Dirk Henrich, Christian Jobin, Elke Schleucher, Ingo Marzi, Mark Lehnert

Get full text

Are Trends in Economic Modeling of Pediatric Diabetes Mellitus up to Date with the Clinical Practice Guidelines and the Latest Scientific Findings? by Roque Cardona-Hernandez, Alberto de la Cuadra-Grande, Julen Monje, María Echave, Itziar Oyagüez, María Álvarez, Isabel Leiva-Gea

“…A multidisciplinary group of experts agreed on the relevant themes to conduct the comparative analysis: parameter informing on glycemic control, diabetic ketoacidosis/hypoglycemia, C-peptide as prognostic biomarker, metabolic memory, age at diagnosis, socioeconomic status, pediatric-specific sources of risk equations, and pediatric-specific sources of utilities/disutilities. …”
Get full text

Algorithm of selecting the tear replacement therapy in ambulatory practice by V.V. Brzheskiy

“…<br> «Artificial tear» preparations containing additional ingredients (metabolic, anti-inflammatory, antioxidant, osmoprotective, etc.) are used depending on the concomitant pathology of the cornea and conjunctiva.…”
Get full text

Impact of COVID-19 on paediatric admissions to a Chinese hospital: a single-centre retrospective chart review by Jie Zheng, Yan-hui Chen

“…The proportions of infection-related diseases (36.3% (455 cases) vs 20.8% (184 cases)), respiratory system-related diseases (22.5% (283 cases) vs 9.4% (83 cases)); and endocrine, nutritional and metabolic diseases (17.1% (214 cases) vs 9.2% (81 cases)) decreased significantly, whereas that of musculoskeletal and connective tissue diseases increased from 11.0% (138 cases) to 20.1% (178 cases), thereby becoming the most common reason for hospitalisation. …”
Get full text

Central obesity is a burden even in normal weight adolescents of a non-metropolitan Indian City: A case for alarm and action for prevention and control by Tabassum Nawab, Zulfia Khan, Iqbal M. Khan, Mohammad A. Ansari

“…Introduction: Central obesity (CO) leads to increased cardiovascular and metabolic risks in children and adolescents. The evidence on prevalence of central obesity and its correlates are lacking among adolescents in India. …”
Get full text

Analysis of the Genomes and Adaptive Traits of <i>Skermanella cutis</i> sp. nov., a Human Skin Isolate, and the Type Strains <i>Skermanella rosea</i> and <i>Skermanella mucosa</i> by Yujin Choi, Munkhtsatsral Ganzorig, Kyoung Lee

“…TT6^T, isolated from human skin, with a focus on its metabolic and environmental adaptations. Genome sequencing and phylogenomic analyses revealed that the strain TT6^T is most closely related to <i>S. rosea</i> M1^T, with average nucleotide identity and digital DNA–DNA hybridization values of 94.14% (±0.5%) and 64.7%, respectively. …”
Get full text

Does candidate race influence simulated patient ratings in standardised assessments of clinical practice? A single-blinded randomised study in UK medical schools by Celia Brown, Amir H Sam, Rachel Westacott, Mark Gurnell, Sarah Khavandi, Malcolm Reed, Ann Sebastian, Kerry Badger

Get full text

Risk of renal complications and death in young and middle-aged Swedes with parental type 1 diabetes: a nation-wide, prospective cohort study by Torbjörn Lind, Marie Fredriksson, Emma Persson, Anna Möllsten

“…Introduction This study aimed to investigate if individuals with childhood-onset type 1 diabetes having a parent with the same condition (parental diabetes) had worse metabolic control and an increased risk of death and renal failure compared with those with parents without type 1 diabetes (sporadic diabetes).Research design and methods We conducted a population-based cohort study using data from the Swedish Childhood Diabetes Register, including cases with onset of type 1 diabetes before the age of 15 and recorded between 1977 and 2010. …”
Get full text

Role of polyethylene glycol to alleviate lead stress in Raphanus sativus by Muhammad Sajid, Shakil Ahmed, Rehana Sardar, Aamir Ali, Nasim Ahmad Yasin

“…Lead (Pb) toxicity causes ionic, oxidative and osmotic injuries which induce various morphological, physiological, metabolic and molecular abnormalities in plants. Polyethylene glycol (PEG) is widely used to elucidate drought stress induction and alleviation mechanisms in treated plants. …”
Get full text

Validation of Aerobic Capacity (VO2max) and Pulse Oximetry in Wearable Technology by Bryson Carrier, Sofia Marten Chaves, James W. Navalta

“…VO2max was assessed through a graded exercise test and an outdoor run, comparing results from the Garmin fēnix 6 to a criterion measurement obtained from a metabolic system. Pulse oximetry involved comparing fēnix 6 readings under normoxic and hypoxic conditions against a medical-grade pulse oximeter. …”
Get full text

High-field MRI findings in epileptic dogs with a normal inter-ictal neurological examination by Stephanie Phillipps, Rita Goncalves

“…To be included in the study, patients had to have a normal neurological examination, high-field MRI of the brain and have had metabolic and toxic causes excluded.ResultsFour hundred and twelve dogs were eligible for inclusion. …”
Get full text

Determinants of Weight Loss following Laparoscopic Sleeve Gastrectomy: The Role of Psychological Burden, Coping Style, and Motivation to Undergo Surgery by Andrea Figura, Anne Ahnis, Andreas Stengel, Tobias Hofmann, Ulf Elbelt, Jürgen Ordemann, Matthias Rose

Get full text