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9621
A randomized comparative effectiveness trial to evaluate two programs for promotion of physical activity after spinal cord injury in manual wheelchair users
Published 2025-02-01“…At final evaluation, diastolic blood pressure after a 6-Minute Push Test was significantly lower in the WODAA group, while no differences were found in distance traveled, systolic, or pre-test diastolic blood pressures. Metabolic bloodwork and shoulder pain scores did not change and were similar between groups.ConclusionDepending on the measure used, these findings suggest that a WODAA approach to PA is comparable or more effective than a traditional PACE program in promoting physical activity in low-active manual wheelchair users with paraplegia.…”
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9622
Genetic mechanisms of the influence of light and phototransduction on Drosophila melanogaster lifespan
Published 2018-11-01“…Increase in motor activity and, as a result, in metabolic rate and thermogenesis during permanent exposure to light also reduces the body's energy reserves and lifespan. …”
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9623
Association between SPISE and NAFLD in patients with type 2 diabetes
Published 2025-01-01“…AimsNon-alcoholic fatty liver disease (NAFLD) is closely related to type 2 diabetes (T2D), with reduced insulin sensitivity being a key factor in their disrupted metabolic processes. The single point insulin sensitivity estimator (SPISE) is a novel index. …”
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9624
Combination model for freshness prediction of pork using VIS/NIR hyperspectral imaging with chemometrics
Published 2025-01-01“…Total bacterial count (TBC) and volatile basic nitrogen (VBN), which exhibited increases correlating with metabolite changes during storage, were designated as freshness indicators. Metabolic contents of the sample were quantified using nuclear magnetic resonance. …”
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9625
The frequency of distribution of the genotypes of the IL4 polymorphism (rs 2243250) in psoriasis and psoriatic arthritis
Published 2019-02-01“…The carriage of the C/T and T/T genotypes in PsA may be associated with the Koebner phenomenon and the metabolic disorders in comparison with PS. Differences in the carriage of the C/C genotypes relative to C/T and T/T IL4 (rs2243250) in psoriasis and psoriatic arthritis were determined. …”
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9626
Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines
Published 2025-01-01“…Three main chemotherapeutic drugs used for the treatment of metastatic colorectal cancer are 5-fluorouracil, oxaliplatin and irinotecan which is metabolized to an active compound SN-38. The main goal of this study was to find the genes connected to the resistance to the aforementioned drugs and to construct a predictive gene expression-based classifier to separate responders and non-responders.MethodsIn this study, we analyzed gene expression profiles of seven patient-derived CRC organoids and performed correlation analyses between gene expression and IC50 values for the three standard-of-care chemotherapeutic drugs. …”
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9627
Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China
Published 2018-08-01“…Pharmacotherapy is recommended in the case of nonalcoholic steatohepatitis (NASH) progression (bridging fibrosis ³ F2 and cirrhosis), as well as the earlier stages of NASH with two and more fibrosis progression risk factors (age over 50 years, diabetes mellitus, metabolic syndrome, alanine transaminase elevation). …”
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9628
Effect of glyphosate on renal function: A study integrating epidemiological and experimental evidence
Published 2025-01-01“…The damage to the kidneys caused by glyphosate may be mediated through the regulation of metabolic pathways, and the specific mechanisms require further experimental investigation.…”
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9629
Causal linkage between adult height and kidney function: An integrated population-scale observational analysis and Mendelian randomization study.
Published 2021-01-01“…In observational analysis, adult height was inversely associated with both eGFRcreatinine (per 1 SD, adjusted beta -1.039, standard error 0.129, P < 0.001) and eGFRcystatinC (adjusted beta -1.769, standard error 0.161, P < 0.001) in a multivariable model adjusted for clinicodemographic, anthropometric, metabolic, and social factors. Moreover, multivariable summary-level MR showed that a taller genetically predicted adult height was causally linked to a lower log-eGFRcreatinine (adjusted beta -0.007, standard error 0.001, P < 0.001) and a higher risk of CKDcreatinine (adjusted beta 0.083, standard error 0.019, P < 0.001). …”
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9630
Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and serum thyroid function measures: Recent Findings from NHANES 2007–201...
Published 2025-01-01“…This suggests that NHHR may reflect changes in thyroid function, highlighting its potential clinical significance in assessing thyroid function and metabolic health.…”
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Delusions of Glass Under Skin: An Unusual Case of Somatic-Type Delusional Disorder Treated with Olanzapine
Published 2022-05-01“…The patient was admitted to the psychiatry service, where organic causes were ruled out (infection, metabolic abnormalities, drug use). The patient received olanzapine 5mg PO nightly treatment with adjunctive psychotherapy and experienced acute psychotic relief after a two-day admission period. …”
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9634
Principles of Rational Nutrition for Managing Constipation
Published 2018-11-01“…Viscous fibres are most capable of swelling, thus exhibiting metabolic effects at the level of the small intestine. …”
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9635
Prediction of Liver Steatosis and Fibrosis Based on Clinical Variables Using a Large National Survey Database
Published 2023-01-01“…On the other hand, sex, tobacco use, metabolic energy expenditure, and serum triglyceride are the least associated with liver fibrosis based on decision tree analysis and a gradient-boosted model. …”
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9636
Factors associated with early-onset androgenetic alopecia: A scoping review.
Published 2024-01-01“…<h4>Background</h4>Early-onset androgenetic alopecia (AGA) has been associated with various chronic conditions, including metabolic syndrome (MetS). Gaining a deep understanding of early-onset AGA may enable earlier intervention in individuals at high risks. …”
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Body fat percentage and Body Mass Index in association with menstrual irregularities in young adults: A cross-sectional study
Published 2024-07-01“…ABSTRACT Objectives: Body fat percentage measures overall amount of fat as a proportion of total body weight. Basal metabolic index (BMI) is an unreliable predictor of body fat percentage as excess fat, lean, muscle, or bone density are indifferentiable. …”
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