GDF-15 Is Associated with Poor Physical Function in Prefrail Older Adults with Diabetes by Reshma Aziz Merchant, Yiong Huak Chan, Gustavo Duque

“…Growth differentiation factor 15 (GDF-15) has been shown to be a metabolic and appetite regulator in diabetes mellitus (DM) and obesity. …”
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The efficacy and safety of Ginkgo biloba L. leaves extract combined with ACEI/ARB on diabetic kidney disease: a systematic review and meta-analysis of 41 randomized controlled tria... by Zehua Zhang, Shiyun Tang, Shiyu Liu, Yulin Leng, Xiaoxu Fu, Hongyan Xie, Hong Gao, Hong Gao, Chunguang Xie, Chunguang Xie

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The Protocol for the Multi-Ethnic, multi-centre raNdomised controlled trial of a low-energy Diet for improving functional status in heart failure with Preserved ejection fraction (... by Noelle Robertson, Melanie J Davies, Thomas Yates, Gerry P McCann, Gaurav Singh Gulsin, Emer M Brady, Joanne V Wormleighton, Eylem Levelt, Oliver Rider, Jiliu Pan, Christopher Miller, Iain Squire, Mehak Asad, Fardad Soltani, Michelle Hadjiconstantinou, Rachel L Brown, Joanna M Bilak

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The Application of Incretin-Based Pharmacotherapy in the Contemporary Management of Type 2 Diabetes: A Review of the Literature by Jakub Waszczyński, Wojciech Kulej, Wiktor Biesiada, Piotr Kulej, Justyna Woźniak, Justyna Weronika Kmieć, Anna Mariia Chernysh, Aleksandra Dusińska, Kamila Fuczyło, Karolina Stankević

“…These drugs also improved glycemic and metabolic parameters, though initial gastrointestinal side effects were common but temporary. …”
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LC-MS/MS-based metabolomic study provides insights into altitude-dependent variations in flavonoid profiles of strawberries by Muhammad Junaid Rao, Muhammad Junaid Rao, Huaizheng Wang, Huaming Lei, Hongcha Zhang, Xiande Duan, Liuyuan Bao, Chengcui Yang, Duo Han, Yongzhi Zhang, Shunqiang Yang, Mingzheng Duan

“…Environmental conditions significantly influence the metabolic composition and quality attributes of fruits. …”
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Combined Effects of Chrysin Supplementation and Exercise Training on Diabetes-Induced Oxidative Stress and Apoptosis in Rat Testicular Tissue by Shiva Cheraghi Abajlou, Asghar Tofighi, Javad Tolouei Azar, Amir Afshin Khaki, Mazdak Razi

“…Background: Diabetes mellitus (DM), one of the most pervasive and enduring metabolic diseases, has been demonstratedto adversely impact male fertility. …”
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Association of Low-Attenuation Plaque with Impaired Glucose Tolerance and Type 2 Diabetes Mellitus in Patients with Suspected Coronary Artery Disease by Thomas R. Andersen, Katrine S. Overgaard, Laurits Juhl Heinsen, Roda Abdulkadir Mohamed, Helle Precht, Jess Lambrechtsen, Søren Auscher, Kenneth Egstrup

“…Patients with IGT demonstrated plaque burden similar to patients with known T2DM, underscoring the need for early metabolic intervention.…”
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Neoandrographolide inhibits mature osteoclast differentiation to alleviate bone loss and treat osteoporosis by Kai Tang, Kai Tang, Kai Tang, Wei Deng, Wei Deng, Wei Deng, Wei Deng, Zhiying Huang, Zhiying Huang, Zhiying Huang, Simin Chen, Simin Chen, Simin Chen, Zilin Zhu, Zilin Zhu, Shukun Lin, Shukun Lin, Lubin Zhong, Lubin Zhong, Quanxin Zheng, Quanxin Zheng, Wenhua Zhao, Wenhua Zhao, Zhida Zhang, Zhida Zhang, Ling Mo, Ling Mo, Ling Mo

“…BackgroundOsteoporosis (OP), as the prevalent systemic metabolic bone disease worldwide, progresses insidiously and slowly. …”
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Polyunsaturated Fatty Acid and S-Adenosylmethionine Supplementation in Predementia Syndromes and Alzheimer's Disease: A Review by Francesco Panza, Vincenza Frisardi, Cristiano Capurso, Alessia D'Introno, Anna M. Colacicco, Alessandra Di Palo, Bruno P. Imbimbo, Gianluigi Vendemiale, Antonio Capurso, Vincenzo Solfrizzi

“…AD is accompanied by reduced GST activity, diminished SAM, and increased S-adenosylhomocysteine (SAH), the downstream metabolic product resulting from SAM-mediated transmethylation reactions, when deprived of folate. …”
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Exercise Training in Athletes with Bicuspid Aortic Valve Does Not Result in Increased Dimensions and Impaired Performance of the Left Ventricle by Laura Stefani, Giorgio Galanti, Gabriele Innocenti, Roberto Mercuri, Nicola Maffulli

“…In any case, the dimensions of the LV remained within normal range. The metabolic requirements of the diverse sport examined in the present investigations do not seem to produce any negative impact in BAV athletes…”
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Revealing novel protein interaction partners of glyphosate in Escherichia coli by Alix Sarah Aldehoff, Dominique Türkowsky, Patrick Lohmann, Masun Nabhan Homsi, Ulrike Rolle–Kampczyk, Elke Ueberham, Jörg Lehmann, Martin von Bergen, Nico Jehmlich, Sven–Bastiaan Haange

“…Overall, glyphosate induced metabolic disturbances in E. coli, extending beyond its primary target, thereby providing new insights into glyphosate’s broader impact on microbial systems.…”
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Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides by Xiaoyi Shi, Chunhui Lai, Lianyu Zhao, Mingying Zhang, Xi Liu, Shanqin Peng, Weizhong Guo, Qiuying Xu, Song Chen, Guang-xing Chen

“…IL-37 is a cytokine that plays critical protective roles in many metabolic inflammatory diseases, and its therapeutic potential has been confirmed by exogenous IL-37 administration. …”
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Metagenomic insights into the development of microbial communities of straw and leaf composts by Anastasiia K. Kimeklis, Anastasiia K. Kimeklis, Grigory V. Gladkov, Olga V. Orlova, Tatiana O. Lisina, Alexey M. Afonin, Alexey M. Afonin, Tatiana S. Aksenova, Arina A. Kichko, Alla L. Lapidus, Evgeny V. Abakumov, Evgeny V. Abakumov, Evgeny E. Andronov

“…Consistent with this, the metagenome analysis showed that the microbiome of straw compost was enriched in genes for metabolic pathways of simpler compounds. At the same time, there were more genes for aromatic compound degradation pathways in leaf litter compost. …”
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MR Imaging of Prostate Cancer: Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology by J. Yamamura, G. Salomon, R. Buchert, A. Hohenstein, J. Graessner, H. Huland, M. Graefen, G. Adam, U. Wedegaetner

“…Sensitivity and specificity of ADC and metabolic ratio (MET)—both separately and in combination—for identification of tumor tissue was computed for variable discrimination thresholds to evaluate its receiver operator characteristic (ROC). …”
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Zinc Supplementation Prevented Type 2 Diabetes-Induced Liver Injury Mediated by the Nrf2-MT Antioxidative Pathway by Lechu Yu, Yuanyuan Liu, Yichun Jin, Tinghao Liu, Wenhan Wang, Xuemian Lu, Chi Zhang

“…This was followed by zinc treatment at 5 mg/kg body weight given every other day for 3 months. Global metabolic disorders of both glucose and lipids were unaffected by zinc supplementation. …”
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Biomarkers of residual risk and all-cause mortality after acute coronary syndrome. by Anna Toso, Mario Leoncini, Mauro Maioli, Simona Villani, Francesco Bellandi

“…Residual risk involves various inflammatory, metabolic and renal factors as well as lipid and thrombotic processes. …”
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Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin by Ziwei Yang, Ziwei Yang, Tixin Han, Ruibin Yang, Ruibin Yang, Yinuo Zhang, Yinuo Zhang, Yifei Qin, Yifei Qin, Yifei Qin, Jialu Hou, Jialu Hou, Fei Huo, Fei Huo, Zhuan Feng, Zhuan Feng, Yaxin Ding, Yaxin Ding, Jiali Yang, Jiali Yang, Gang Zhou, Gang Zhou, Shijie Wang, Shijie Wang, Xiaohang Xie, Xiaohang Xie, Peng Lin, Peng Lin, Zhi-Nan Chen, Zhi-Nan Chen, Jiao Wu, Jiao Wu

“…Imidazole ketone erastin (IKE), an inhibitor of the system Xc– functional subunit solute carrier family 7 member 11 (SLC7A11), is an effective and metabolically stable inducer of ferroptosis with potential in vivo applications. …”
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Comparative response mechanisms of two cultivars of Musa paradisiaca L. to Fusarium oxysporum f.sp. cubense infection by Yajie Duan, Yajie Duan, Zhiwei Jia, Zhiwei Lu, Huigang Hu, Rulin Zhan

“…Through an in-depth exploration of the metabolic pathways that bolster this defense, we identified genes associated with resistance to Fusarium oxysporum f. sp. cubense (Foc). …”
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Genetic Variants Flanking the FGF21 Gene Were Associated with Renal Function in Chinese Patients with Type 2 Diabetes by Weihui Yu, Hong Zhu, Xiong Chen, Xuejiang Gu, Xingxing Zhang, Feixia Shen, Weiping Jia, Cheng Hu

“…Fibroblast growth factor 21 (FGF21) is closely linked with metabolic disorders including diabetes. Evidences suggested that FGF21 may play a protective role against diabetic kidney disease (DKD). …”
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Surgical frequency analysis of patients clustered according to postoperative pain trajectory: a retrospective study by Qurani Alifitriah Tartar, Kyung Nam Park, Kwang-Suk Seo, Myong-Hwan Karm

“…Exclusion criteria were COPD, head injury, adverse drug reactions, substance misuse, severe metabolic disorders, infections, or psychiatric conditions. …”
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