Влияние курсового приема L-орнитин- L-аспартата на фиброз и стеатоз печени у больных ассоциированной с нарушениями метаболизма жировой болезнью печени (неалкогольной жировой болезн... by Е. V. Garanina

“…Hyperammonaemia develops both in cirrhosis and earlier fibrotic stages during metabolic-associated fatty liver disease (MAFLD). Besides neurotropic, ammonia exerts the hepatotoxic and profibrotic effects. …”
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Search for differentially methylated regions in ancient and modern genomes by D. D. Borodko, S. V. Zhenilo, F. S. Sharko

“…In this study, we attempted to develop an algorithm for identifying differentially methylated regions associated with metabolic syndrome, which have undergone methylation changes in humans during the transition from a hunter­gatherer to a sedentary lifestyle. …”
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Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes by Pawan Shrestha, Amy E. Whelchel, Sarah E. Nicholas, Wentao Liang, Jian-Xing Ma, Dimitrios Karamichos

“…Diabetes mellitus (DM) is a group of metabolic diseases that is known to cause structural and functional ocular complications. …”
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2D-Shear Wave Elastography in the Evaluation of Parathyroid Lesions in Patients with Hyperparathyroidism by Ioana Golu, Ioan Sporea, Lavinia Moleriu, Anca Tudor, Marioara Cornianu, Adrian Vlad, Romulus Timar, Melania Balas, Daniela Amzar, Mihaela Vlad

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Simultaneous Inhibition of PGE2 and PGI2 Signals Is Necessary to Suppress Hyperalgesia in Rat Inflammatory Pain Models by Ryusuke Sugita, Harumi Kuwabara, Kazufumi Kubota, Kotaro Sugimoto, Toshihiro Kiho, Atsushi Tengeiji, Katsuhiro Kawakami, Kohei Shimada

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Sensitivity Analysis with the Monte Carlo Method and Prediction of Atenolol Removal Using Modified Multiwalled Carbon Nanotubes Based on the Response Surface Method: Isotherm and K... by Mohammad Mehdi Amin, Nasrin Bagheri, Farzaneh Mohammadi, Bahare Dehdashti

“…Because the human body cannot metabolize it completely, this drug has been commonly found in many environmental matrices. …”
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Characterization of Streptomyces Isolates Associated with Estuarine Fish Chanos chanos and Profiling of Their Antibacterial Metabolites-Crude-Extract by Muhammad A. Kurnianto, Harsi D. Kusumaningrum, Hanifah N. Lioe

“…Qualitative HPLC profiling revealed that the metabolic-crude-extracts showed many peaks with intensive area at 210 and 214 nm, especially from SCA-11 and AIA-10, indicating the presence of peptide groups in the structure of the constituent compound. …”
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A scanning electron microscopic studies on the podocytes of the kidneys of rat (rattus norvegicus) and blind mole rat (spalax leucodon) by İsmail Hakkı Nur, Atila Yoldaş, Aydın Alan, Aytaç Akçay

“…Contrary most rodents, they can carry out high levels of metabolic rate under these conditions. The present study aimed out to compare the blind mole rats and rats's renal podocyte, an important cell for maintaining the normal structure and function of the glomerulus.…”
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A twin-driven analysis on early aging biomarkers and associations with sitting-time and physical activity. by Ryan Bruellman, Shandell Pahlen, Jarrod M Ellingson, Robin P Corley, Sally J Wadsworth, Chandra A Reynolds

“…<h4>Conclusions</h4>Our findings support the counteracting influence of prolonged sitting and physical activity on indicators of cardiovascular and metabolic health. A compensating role of vigorous activity on sitting health links is indicated while reducing sitting time appears paramount. …”
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Efficacy of Single-Pill Combination of Telmisartan 80 mg and Hydrochlorothiazide 25 mg in Patients with Cardiovascular Disease Risk Factors: A Prospective Subgroup Analysis of a Ra... by Harold Bays, Pingjin Gao, Birgit Völker, Michaela Mattheus, Luis M. Ruilope, Dingliang Zhu

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Akin Ogundiran: The Historian and Archaeologist of Yoruba-Atlantic becomes Chancellor Professor at the University of North Carolina at Charlotte by Toyin Falola

“…In my book, The African Diaspora: Slavery, Modernity and Globalization, I devoted Chapter 10 to his oeuvre, stating in one of the key paragraphs that: 268 Toyin Falola In connecting West Africa to the Atlantic economy, Ogundiran is pointing to what could be characterized as the metabolic rift between supply and demand; African economies were on the supply side of the global division of labor that compelled them to produce for the Atlantic economy and, at the same time, to consume products from external sources. …”
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A comprehensive analysis of trends in the burden of gout in China and globally from 1990 to 2021 by Shiwei Xie, Heng Xiao, Lei Xu, Gengwu Li, Fan Zhang, Mingwei Luo

“…Abstract Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. …”
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Cerebral 18F-FDG PET in macrophagic myofasciitis: An individual SVM-based approach. by Paul Blanc-Durand, Axel Van Der Gucht, Eric Guedj, Mukedaisi Abulizi, Mehdi Aoun-Sebaiti, Lionel Lerman, Antoine Verger, François-Jérôme Authier, Emmanuel Itti

“…<h4>Conclusion</h4>We developed an original and individual approach including a SVM to classify patients between healthy or MMF metabolic brain profiles using 18F-FDG-PET. Machine learning algorithms are promising for computer-aided diagnosis but will need further validation in prospective cohorts.…”
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Systematic review on the effects of exercise with and without breakfast consumption on cognitive performance in healthy adults by Shu-Shih Hsieh, Yu Tian, Chun-Yuan Cheng, Yung-Chih Chen

“…Further investigation regarding interactive effects of breakfast and exercise on cognition, especially in individuals with metabolic disease or medical conditions, is warranted.…”
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Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells by Lidan Xue, Lili Huang, Yajing Tian, Xin Cao, Yu Song

“…Along with blood glucose levels, diabetic retinopathy (DR) development also involves endogenous risk factors, such as trimethylamine-N-oxide (TMAO), a product of intestinal flora metabolic disorder, which exacerbates diabetic microvascular complications. …”
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Evaluation of Overall Survival Predictions In Inoperable Pancreas Ductal Adenocarcinoma by Hasan Önner, Mustafa Erol, İlknur Küçükosmanoğlu

“…In the Kaplan-Meier analysis, the median OS duration of the patients with a median value of TLGbelow 298.34 was 13.87 months, while the median OS duration was found to be 4.97 months in patients with a TLGvalue above this value.Conclusion: In our study, TLG value, which is an FDG PET/CT parameter that reflects both the metabolic activity andthe volume of the tumor, was found to be the only independent predictor of the OS of inoperable PDAC patients.TLG can be used as a potential biomarker for survival in patients with inoperable PDAC and may assist precisionmedicine applications.…”
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Risk of autism spectrum disorder at 18 months of age is associated with prenatal level of polychlorinated biphenyls exposure in a Japanese birth cohort by Hirokazu Doi, Akira Furui, Rena Ueda, Koji Shimatani, Midori Yamamoto, Akifumi Eguchi, Naoya Sagara, Kenichi Sakurai, Chisato Mori, Toshio Tsuji

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A retrospective study of 5S behaviours of Physical Activity (PA) among suburban Mumbai population with Type 2 Diabetes Mellitus (T2DM) by Kosha Parikh, Shikha Thosani, Ameya Joshi, Apoorva Hajirnis, Chandani Seth

“…Background: T2DM is a chronic metabolic disorder to manage the same lifestyle modification is cornerstone. …”
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The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4 by Wenjuan Zhang, Yan Hu, Wenbing Zhang, Ke Yi, Xiaohui Xu, Zhihua Chen

“…GSEA analysis suggested that the SALL4 upregulated the GO and pathway of growth and cancer development and downregulated metabolization pathway. The relationship between lymph node metastasis, histological grading, clinical staging, and the expression of SALL4 in carcinoma tissues was analyzed. …”
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Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment by Liu Y, Si L, Jiang Y, Jiang S, Zhang X, Li S, Chen J, Hu J

“…Yunheng Liu,1,&ast; Longqing Si,1,&ast; Yuxuan Jiang,1,&ast; Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. …”
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