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9401
Evaluation of the Antioxidant and Cytotoxic Activities on Cancer Cell Line of Extracts of Parasitic Plants Harvested in Tunisia
Published 2020-06-01“…The antioxidant activity of hexane, ethyl acetate, acetone, methanol, and water extracts obtained by sequential maceration was estimated by DPPH, ABTS and FRAP assays. The metabolic profiles of aqueous extracts were studied by 1 H NMR spectroscopy. …”
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9402
Chemical Characterization and Differential Lipid-Modulating Effects of Selected Plant Extracts from Côa Valley (Portugal) in a Cell Model for Liver Steatosis
Published 2025-01-01“…Given their rich ethnomedicinal history, we evaluated their protective effects on an in vitro model of metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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9403
Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma
Published 2025-01-01“…Specific malignant cell subtypes strongly associated with MVI were identified, exhibiting distinctive gene expression patterns related to proliferation, invasion, and metabolic reprogramming of tumour cells. Further analysis revealed that the laminin and VEGF signalling pathways are crucial for remodelling the tumour microenvironment and angiogenesis associated with MVI. …”
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9404
Transcriptome and DNA methylation analysis of the goat pineal gland during puberty
Published 2025-01-01“…Genes regulated by DNA methylation regulates genes primarily involved in metabolic processes, oxidative phosphorylation, and signaling pathways related to thermogenesis. …”
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9405
Prevalence of dyslipidaemia and transaminitis in obese 8 to 18-year-old in Eastern India
Published 2024-10-01“…Keywords: obesity; childhood; adolescence; lipid profile; dyslipidaemia; NAFLD; metabolic syndrome…”
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9406
A new peptide inhibitor of C1QBP exhibits potent anti‐tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombina...
Published 2025-01-01“…Concomitantly, due to metabolic adaptability, we have observed an up‐regulation of glycolysis to compensate for OXPHOS inhibition. …”
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9407
Solitary metastasis in the internal auditory canal from non-small cell lung carcinoma: A case report
Published 2025-01-01“…A subsequent PET CT scan indicated a complete metabolic response. Eighteen months later, the patient presented with rapidly progressing vertigo, left-sided facial palsy, and hearing loss. …”
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9408
Unraveling the relationship between obstructive sleep apnea and osteoarthritis: A multivariate mendelian randomization highlighting the role of BMI as a confounding factor
Published 2025-01-01“…Future research should aim to validate these findings in diverse populations and explore other metabolic pathways that may contribute to these complex associations.…”
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9409
Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
Published 2024-12-01“…Data was collected from established ASCVD patients attending cardio-metabolic clinics at tertiary care centers between December 2021 and December 2023. …”
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9410
Intralymphatic Glutamic Acid Decarboxylase-Alum Administration Induced Th2-Like-Specific Immunomodulation in Responder Patients: A Pilot Clinical Trial in Type 1 Diabetes
Published 2018-01-01“…Patients from the LN group with best metabolic outcome seemed to have common immune correlates related to the treatment. …”
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9411
The Renal and Liver Complications Development among Patients with Type 2 Diabetes Mellitus in Kirkuk City
Published 2022-06-01“… Diabetes is a chronic metabolic malady that has raised levels of blood glucose, which in last, it will cause severe harms to the heart, blood vessels, eyes, kidneys, and nerves. …”
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9412
Torovirus infection in animals: a review
Published 2023-06-01“…Massive digestive disorders of neonatal calves, clinically manifested as diarrhea causing severe dehydration, toxemia, immunodeficiency and metabolic disorders, induce huge economic losses in animal husbandry. …”
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9413
Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives
Published 2024-12-01“…Glucocorticoids (GCs) are routinely used to treat hematological malignancies; however, long-term treatment with GCs can lead to atrophic and metabolic adverse effects. Selective glucocorticoid receptor agonists (SEGRAs) with reduced side effects may act as a superior alternative to GCs. …”
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9414
Assessment of caries diagnostic threshold of DMFT, and ICDAS II in the estimation of caries prevalence rate in first permanent molars among students of College of Dentistry-Hawler...
Published 2024-03-01“… Background: Dental caries is a common chronic infectious disease resulting from tooth-adherent cariogenic bacteria primarily S. Mutans, which metabolize sugars to produce acid, demineralizing the tooth structure over time. …”
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9415
DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis
Published 2021-01-01“…It is considered that the transformation of normal cells to cancerous ones involves “recoding” of certain metabolic pathways. Diacylglycerol O-acyltransferase 1 (DGAT1) can synthesize triglycerides by transferring acyl-CoA to diacylglycerol, which plays a key role in lipid synthesis. …”
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9416
Evaluation of the Antioxidant Properties and Biological Effects of a Novel Combined Barberry Root–Propolis Extract on HEK293T Cells
Published 2024-12-01“…Their effect on HEK293T cells was monitored in real-time by using the xCELLigence system which recorded changes in the proliferative activity (PA). The metabolic activity (MA) was evaluated using an MTS test and cell migration was analyzed via a scratch assay. …”
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9417
Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis
Published 2020-10-01“…Abstract The high fat diet alters intestinal microbiota due to increased intestinal permeability and susceptibility to microbial antigens leads to metabolic endotoxemia. But probiotic juices reported for various health benefits. …”
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9418
Butyric Acid Modulates Gut Microbiota to Alleviate Inflammation and Secondary Bone Loss in Ankylosing Spondylitis
Published 2024-12-01“…<b>Conclusions:</b> These beneficial effects were attributed to the modulation of gut microbiota, anti-inflammatory properties, and the maintenance of skeletal metabolic homeostasis. This study contributes new evidence supporting the relationship between gut microbiota and bone health.…”
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9419
Good Tolerance of Citrate Accumulation due to Plasma Exchange among Patients with Acute-on-Chronic Liver Failure: A Prospective, Observational Study
Published 2018-01-01“…Hypocalcemia (ionized calcium) and mild alkalosis were the main metabolic alterations. No symptoms associated with hypocalcemia occurred. …”
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9420
Bovine nebovirus infection (review)
Published 2023-12-01“…Digestive disorders clinically manifested by diarrhea resulting in apparent dehydration, toxemia, enophthalmos, membrane pathology, immunodeficiency and metabolic disorders are prevalent among neonatal calf diseases in early postnatal period. …”
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