Exploration of the molecular mechanism behind a novel natural genic male-sterile mutation of 1205A in Brassica napus by Lijing Xiao, Jinze Zhang, Shaomin Guo, Hairun Jin, Qingjing Ouyang, Xu Long, Zhongbin Yan, Entang Tian

“…Furthermore, the subcellular localization of BnaC03g27700D was examined. Metabolic fluctuations associated with the fertility gene were observed, particularly in processes related to aborted tapetal programmed cell death (PCD), which may contribute to reduced pollen fertility with abnormal pollen exine. …”
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Effects of Resveratrol on the Kidney in Rats with Streptozotocin Induced Diabetic Nephropathy by Duygu Tozcu, Çiğdem Özer, Aydan Babül, Sevim Ercan, Ergin Dileköz, Gülnur Take Kaplanoğlu, Güleser Göktaş

“…RSV(10 mg/kg/day) was administered orally by gavage for 8 weeks. Metabolic analyses were conducted throughout the study. …”
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Toward an Efficient Differentiation of Two <i>Diaporthe</i> Strains Through Mass Spectrometry for Fungal Biotyping by Kathleen Hernández-Torres, Daniel Torres-Mendoza, Gesabel Navarro-Velasco, Luis Cubilla-Rios

“…Considering that fungi display a great morphological, ecological, metabolic, and phylogenetic diversity, their taxonomic identification is extremely important because it helps us establish important information about each species and its possible biochemical and ecological roles. …”
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Metabolomic approach to investigate <i>Dactylis glomerata</i> L. from the VIR collection by N. Yu. Malysheva, T. V. Shelenga, A. E. Solovyeva, T. B. Nagiev, N. V. Kovaleva, L. L. Malyshev

“…The article considers the metabolic profiles of 15 accessions of the cocksfoot from the collection of the N.I. …”
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Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…Dysfunctional autophagy has been implicated in the development of various diseases, including cancer, neurodegenerative disorders, metabolic diseases, and bacterial or viral infections. …”
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Thyroid response to blocking sympathetic activity in chronic cold-exposed hunters in East Greenland: a case–control study by Mette Motzfeldt Jensen, Charlotte Elberling Almasi, Hans Christian Florian-Sørensen, Stine Linding Andersen, Stig Andersen

“…Greenlandic hunters provide a unique model for evaluating metabolic effects of cold exposure. Aim: We aimed to explore the dynamics of thyroid hormones when blocking sympathetic activity in Greenlandic hunters during winter to inspire knowledge on mechanisms of BAT activation. …”
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Real world efficacy and safety of the advanced hybrid closed-loop system MiniMed 780G (SmartGuard) in children under 7 years of age by Sara López-López, Cristina Díaz-Martín, Inés García-de Pablo, María Teresa Ovejero-Garcia, María Beatriz Garnier-Rodríguez, Ruth Molina-Suárez, Cristina Ontoria-Betancort, Blanca Sáez-Gallego, Ángela Domínguez-García, Sofía Quinteiro-González, Lourdes Travieso-Suárez, María Fátima Cabrera-Guedes, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina

“…ObjectiveTo evaluate the safety and efficacy of the Medtronic 780G SmartGuard™ AID system in children under 7 years of age with type 1 diabetes (T1D).MethodsRetrospective analysis of data from children living with T1D under 7 years of age using the MiniMed 780G™ across three pediatric endocrinology units in the Canary Islands. Metabolic control parameters were analyzed from 14 days of pretreatment to 12 months of follow-up.ResultsThe study included 61 children under 7 years of age, 35 in Group 1 and 26 in Group 2. …”
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Proteomic insights into dual-species biofilm formation of E. coli and E. faecalis on urinary catheters by Kidon Sung, Miseon Park, Ohgew Kweon, Angel Paredes, Alena Savenka, Saeed A Khan

“…E. coli exhibited a more proactive response, emphasizing motility, transcription, and protein synthesis for biofilm establishment; whereas E. faecalis displayed a more reserved strategy, potentially downregulating metabolic activity, transcription, and translation in response to cohabitation with E. coli. …”
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Dysbiosis of Gastric Mucosal Fungal Microbiota in the Gastric Cancer Microenvironment by Zhenzhan Zhang, Hao Feng, Yaopeng Qiu, Zhou Xu, Qingfeng Xie, Wenfu Ding, Hao Liu, Guoxin Li

“…Functional prediction indicated that the positive expression of Solicoccozyma in tumors was associated with the amino acid- and carbohydrate-related metabolic pathways in GC. Conclusions. This study revealed a novel perspective on the role of Solicoccozyma in tumors and a theoretical basis for therapeutic targets against GC.…”
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Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis by Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang

“…Pseudotime analysis indicates that gene expression, translation, ATP metabolic process, and microtubule-based process are involved in the transition of germ cell types. …”
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Comparison of BTX Profiles and Their Mutagenicity Assessment at Two Sites of Agra, India by Vyoma Singla, Tripti Pachauri, Aparna Satsangi, K. Maharaj Kumari, Anita Lakhani

“…Extracts of samples were positive in both Salmonella typhimurium tester strains TA98 and TA100 without metabolic activation suggesting the presence of direct mutagens in ambient air that can cause both frame-shift and base-pair mutation. …”
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Atrial flutter/fibrillation in adult congenital heart disease: Insights from a large Asian cohort by Shuenn-Nan Chiu, Wei-Chieh Tseng, Chun-Wei Lu, Ming-Tai Lin, Chun-An Chen, Jou-Kou Wang, Mei-Hwan Wu

“…Incidence of AF/AFL increased with age and was higher in patients with pulmonary hypertension (PH), severe CHD, and metabolic syndrome. We found a progressive trend in the onset age of arrhythmia: AFL at a younger age, followed by paroxysmal and sustained AF. …”
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A Comparative Transcriptomic Analysis of Human Placental Trophoblasts in Response to Pathogenic and Probiotic Enterococcus faecalis Interaction by Qianglai Tan, Zhen Zeng, Feng Xu, Hua Wei

“…GO analysis revealed that these DEGs were mainly related to cellular and metabolic processes and biological regulation. However, 28 and 44 DEGs were classified into terms associated with placental and embryonic development in Symbioflor 1 and V583 treatment groups, respectively. …”
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Responses of α-amylase and protease activity to chemical agents and metallic salts in barley seeds (Hordeum vulgare L.) by Amin Hossain, Umma Fatema Shahjadee, Abu Tareq Mohammad Abdullah, Mohammad Nazrul Islam Bhuiyan, Anjum Zerin Rupa

“…Enzymes play a crucial role in maintaining homeostasis in the metabolic processes that sustain life. Understanding what regulates enzyme activity is crucial for many scientific and industrial endeavors. …”
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Molecular Mechanism of Germinated Foxtail Millet Bioactive Peptides in Attenuating Copper-induced Oxidative Damage in Caenorhabditis elegans by Huiqi ZHANG, Xiao CHEN, Xueling JIN, Jingjing LI, Juanli YUAN, Jinyan GAO, Hongbing CHEN, Yong WU

“…At the genetic level, GRBPs mainly regulated the structural constituent of cuticle and the expression of genes related to cytochrome enzyme P450 in C. elegans. At the metabolic level, GRBPs mainly regulated the content of biosynthesis of plant secondary metabolites in C. elegans. …”
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Ionizing radiation and photodynamic therapy lead to multimodal tumor cell death, synergistic cytotoxicity and immune cell invasion in human bladder cancer organoids by Annabell Reinhold, Annegret Glasow, Sandra Nürnberger, Annett Weimann, Lucie Telemann, Jens-Uwe Stolzenburg, Jochen Neuhaus, Mandy Berndt-Paetz

“…Results: PDT and/or IR resulted in concentration-dependent reduction of metabolic activity, organoid diameter and integrity. …”
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The triglyceride–glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with... by Chenyang Li, Zixi Zhang, Xiaoqin Luo, Yichao Xiao, Tao Tu, Chan Liu, Qiming Liu, Cancan Wang, Yongguo Dai, Zeying Zhang, Cheng Zheng, Jiafeng Lin

“…Insulin resistance (IR) plays a crucial role in HTN-related metabolic dysfunction, but its assessment remains challenging. …”
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Elevated Serum Extracellular Vesicle‐Packaged SPARC in Hypertension: A Cross‐Sectional Study in a Middle‐Aged and Elderly Population by Xueying Chen, Han Guo, Xinwei Li, Yang Liu, Xinxin Li, Zhengshuo Cui, Huijuan Ma, Jianxun He, Zhechun Zeng, Huina Zhang

“…Secreted protein acidic and rich in cysteine (SPARC) is involved in many metabolic diseases and endothelial dysfunction pathological processes. …”
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Higher Physical Activity is Associated with Reduced Lower Urinary Tract Symptoms in Korean Men by Seo Eun Hwang, Jae Moon Yun, Su Hwan Cho, Kyungha Min, Ji Young Kim, Hyuktae Kwon, Jin Ho Park

“…PA was quantified in metabolic equivalent (MET)-hours per week, and LUTS severity was assessed using the international prostate symptom score. …”

Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice by Weimin Guo, Nicholas Crossland, Jimmy W. Crott

“…At the end of the study hepatic Cyp2E1, an enzyme that metabolize AOM, was lower in males than females. Livers from MED diet mice were significantly lighter, had lower histologic Non-Alcoholic Fatty Liver Disease (NAFLD) scores, and contained less triglycerides than WRN mice. …”
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