The relationship of body mass index with fasting blood glucose in type-2 diabetes mellitus by Rimadhani Ervina Tria, Mawardi Fitriana, Dewi Fitria Puspita, Purwanta Barkah Djaka, Sholikah Amanatus, Hutomo Muhammad Agita

“…Diabetes mellitus is a metabolic disorder caused by high blood sugar levels. …”
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Neurodegeneration in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy by Elena Garcia-Martin, Marta Cipres, Isabel Melchor, Laura Gil-Arribas, Elisa Vilades, Vicente Polo, Maria Jesus Rodrigo, Maria Satue

“…Patients with type 2 DM without diabetic retinopathy and good metabolic control present neurodegeneration affecting neurons in the macular area and axons in different sectors of the optic disc. …”
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Development of a Komagataella phaffii cell factory for sustainable production of ( +)-valencene by Jintao Cheng, Jiali Chen, Dingfeng Chen, Baoxian Li, Chaozhi Wei, Tao Liu, Xiao Wang, Zhengshun Wen, Yuanxiang Jin, Chenfan Sun, Guiling Yang

“…High expression of key genes IDI1, tHMG1, ERG12 and ERG19 enhanced metabolic flux of MVA pathway, and the yield of ( +)-valencene was further increased by 27%. …”
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Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars by A. A. Traspov, O. V. Kostyunina, A. A. Belous, T. V. Karpushkina, N. A. Svejenceva, N. A. Zinovieva

“…Identifying genome regions that are directly or indirectly associated with developmental defects and malformations in domesticated pigs can help identify genomic traits used as biomarkers of the structural and functional composition of the body, their metabolic status and genetic diseases as well. Such studies are directly related to the improvement of the economic efficiency, as they allow identification and exclusion of defect animals, who may carry target genes not appearing phenotypically, from the breeding process. …”
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Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis by Ningning Yue, Hailan Zhao, Peng Hu, Yuan Zhang, Chengmei Tian, Chen Kong, Zhiliang Mai, Longbin Huang, Qianjun Luo, Daoru Wei, Ruiyue Shi, Shaohui Tang, Yuqiang Nie, Yujie Liang, Jun Yao, Lisheng Wang, Defeng Li

“…First, L. reuteri-CMVs selectively promoted the proliferation of the beneficial bacterium Akkermansia muciniphila (AKK) by upregulating the expression of glycosidases (beta-N-acetylhexosaminidase and alpha-N-acetylglucosaminidase) involved in glycan degradation and metabolic pathways and restored the disrupted gut microbiota balance. …”
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Primary and Secondary Hypogonadism in Male Persons with Diabetes Mellitus by João Martin Martins, Mafalda de Pina Jorge, Catarina Martins Maia, João Roque, Carlos Lemos, Daniel Nunes, Dinis Reis, Catarina Mota

“…Low TT levels were related to older age, poor metabolic control, metformin and statins use, and microvascular disease.…”
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Metabolite Profiling of Sorghum Seeds of Different Colors from Different Sweet Sorghum Cultivars Using a Widely Targeted Metabolomics Approach by Yaxing Zhou, Zhenguo Wang, Yan Li, Zhigang Li, Hui Liu, Wei Zhou

“…To study the diversity and cultivar-specificity of phytochemicals in sweet sorghum seeds, widely targeted metabolomics was used to analyze the metabolic profiles of the white, red, and purple seeds from three sweet sorghum cultivars Z6, Z27, and HC4. …”
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Transforming monosaccharides: Recent advances in rare sugar production and future exploration by Shin-ichi Nakakita, Jun Hirabayashi

“…After the birth of life, the “chemical origin” saccharides thus survived were transformed into a variety of “bricolage products”, which include galactose and other recognition saccharides like fucose and sialic acid through the invention of diverse metabolic pathways (biological evolution era). The remaining monosaccharides that have deviated from this scenario are considered rare sugars. …”
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Effect of Cell Growth and Proliferation Factors (EGF/PDGF Signaling Pathway) on the Etiopathogenesis of Intrauterine Growth Restriction by Serhan Can İşcan, Erhan Demirdağ, Melek Yaman, Emin Ümit Bağrıacık, Merih Bayram

“…The genetic causes of IUGR can be revealed by investigating these metabolic pathways. This study differs from previous IUGR studies, which focused on one or a few genes, because all the gene groups in the EGF/PDGF pathway that may be associated with IUGR were investigated.…”
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Serum proteomic and metabolomic profiling of hepatocellular carcinoma patients co-infected with Clonorchis sinensis by Zeli Tang, Zeli Tang, Zeli Tang, Caibiao Wei, Xueling Deng, Qiumei Lin, Qiping Hu, Qiping Hu, Qiping Hu, Shitao Li, Jilong Wang, Yuhong Wu, Dengyu Liu, Dengyu Liu, Dengyu Liu, Min Fang, Min Fang, Tingzheng Zhan, Tingzheng Zhan, Tingzheng Zhan

“…Proteomic and metabolomic analyses revealed metabolic reprogramming caused by C. sinensis, with excessive depletion of argininosuccinate synthase (ASS) and D-glucose as potential factors in C. sinensis-associated HCC malignancy. …”
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Qualitative and quantitative characteristics of black patch trait in Oujiang color common carp by Ke Jing, Huifan Chen, Nusrat Hasan Kanika, Penghui Zhang, Roland Nathan Mandal, Chunxiao Zeng, Zhiyi Zhang, Jun Wang, Chenghui Wang

“…The melanin content and tyrosinase activity, melanin metabolic enzyme activity of the skin in the hybrid were in the middle between the parents RB and WW. …”
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Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells? by Jordi Pétriz, José Enrique O’Connor, Mercè Carmona, Joan García‐López

“…Cellular drug resistance, which involves several mechanisms such as P‐glycoprotein (P‐gp) overexpression, kinetic and metabolic quiescence, or the increase in the intracellular levels of glutathione, limits the effectiveness of cancer treatment. …”
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Performance improvements and increased ruminal microbial interactions in Angus heifers via supplementation with native rumen bacteria during high-grain challenge by Fan Yang, Madison T. Henniger, Andrew S. Izzo, Emily A. Melchior, Brooke A. Clemmons, Mary A. Oliver, James R. Gaffney, Cameron Martino, Taylor B. Ault-Seay, Miranda L. Striluk, Jordan J. Embree, Juan F. Cordero-Llarena, Pierre-Yves Mulon, David E. Anderson, Mallory M. Embree, Phillip R. Myer

“…Additionally, administration of NRM to animals on a high-grain diet, improved ruminal microbiome stability (P < 0.001), potentially encouraging the conversion of rumen lactate to propionate over time via the succinate pathway and alleviating metabolic stress.…”
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Inhibition of anti-tumour reactivity of immune cells in the salivary gland cancer: A proteomic approach by Rajdeep Chakraborty, Charbel Darido, Aidan Tay, Thiri Zaw, Shoba Ranganathan, Fei Liu, Giuseppe Palmisano

“…Results: Analysis of the acquired data showed that the overexpressed proteins in the OSCC cells and participated more in metabolic process, while in the salivary gland cancer cells, overexpressed proteins participated more in immune processes, immune checkpoint pathway. …”
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Subtle genomic differences in Klebsiella pneumoniae sensu stricto isolates indicate host adaptation by Bridget O'Brien, Alla Yushchenko, Jinha Suh, Dongyun Jung, Zhangbin Cai, Ngoc Sang Nguyen, Makeda Semret, Simon Dufour, Séamus Fanning, Jennifer Ronholm

“…These gene clusters may be positively selected due to the unique metabolic environment of the mammary gland, where lactose, citrate-bound iron, and amino acids like histidine and arginine provide growth advantages for KpI during mastitis. …”
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Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-κB-Dependent Inflammatory/Catabolic Environment of Osteoarthritis by Carola Cavallo, Giulia Merli, Nicoletta Zini, Stefania D’Adamo, Luca Cattini, Michele Guescini, Brunella Grigolo, Alessandro Di Martino, Spartaco Santi, Rosa Maria Borzì, Giuseppe Filardo

“…This is important in the clinical perspective where many OA patients are also affected by the metabolic syndrome (MetS). ADSC from MetS OA patients are dysfunctional and “inflammatory” primed within the adipose tissue. …”
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Bioactive potential and storage behavior of low molecular mass peptides in Pilsner and IPA style craft beers by Roberta Nogueira Pereira da Silva, Angelica Priscila Parussolo Tonin, Gabriela Soares Macello Ramos, Juliana Furtado Dias, Eduardo Cesar Meurer, Maria Gabriela Bello Koblitz

“…These activities are associated with reduced risk of high blood pressure and metabolic syndrome. After 3 months of storage, peptide intensity decreased in Pilsner samples but increased in IPA samples. …”
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Medicinal Plants as a Drug Alternative Source for the Antigout Therapy in Morocco by Nour Elhouda Daoudi, Mohamed Bouhrim, Hayat Ouassou, Mohamed Bnouham

“…Background. The gout is a metabolic disease that is associated with a high level of uric acid in the blood. …”
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Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells by Alessio Cimmino, Magda Gioia, Maria Elisabetta Clementi, Isabella Faraoni, Stefano Marini, Chiara Ciaccio

“…Cancer cells demonstrate remarkable resilience by adapting to oxidative stress and undergoing metabolic reprogramming, making oxidative stress a critical target for cancer therapy. …”
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The Impact of Astaxanthin Supplementation on the Lipid Profile by Filip Arczewski, Michalina Wójcikiewicz, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…Consequently, there is a need for larger, well-standardized clinical trials to accurately assess the efficacy and safety of astaxanthin as a therapeutic agent for lipid modulation and the prevention of metabolic disorders. Future research should focus on robust methodological designs and standardized supplementation protocols to clarify AST’s role in managing dyslipidemia and enhancing cardiovascular health.  …”
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