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9221
Brain Iron Deposition Alterations in Type 2 Diabetes Mellitus Patients With Mild Cognitive Impairment Based on Quantitative Susceptibility Mapping
Published 2025-01-01“…In addition, we analyzed the moderation effects of grey matter volume (GMV) of the related brain areas and several metabolic and cerebrovascular factors on the associations between MSV of ROIs and cognitive characteristics. …”
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9222
Alterations in fecal bacteriome virome interplay and microbiota-derived dysfunction in patients with schizophrenia
Published 2025-01-01“…Additionally, we construct a latent serial mediation model (SMM) to investigate the effect of the gut virome on SCZ through the bacteriome and host metabolic profile. SCZ patients exhibited a decreased gut bacterial β-diversity compared to HCs, with seven differentially abundant bacteria, including Coprobacillaceae, Enterococcaceae etc. …”
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9223
Incidence rate and associated patient characteristics of liver disease in Wales 2004–2022: a retrospective population-scale observational study
Published 2025-02-01“…A total of 79 992 individuals (72%) entered the cohort with the underlying aetiology of liver disease, including alcohol-related liver disease, non-alcoholic fatty liver disease (NAFLD), viral hepatitis, metabolic, haemochromatosis and autoimmune liver diseases. …”
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9224
Evolution of Functional and Paraclinical Markers as Predictive Factors in Pediatric Late-Onset SMA Under Nusinersen Treatment: The Role of CSF pNF-H
Published 2025-12-01“…Following nusinersen treatment, pNF-H levels stabilized at low values, likely due to basal metabolic activity. In SMA types 2 and 3, higher baseline CSF pNF-H levels correlated with improved performance over time. …”
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9225
Blood metabolomic profile in patients with type 2 diabetes mellitus with diabetic peripheral neuropathic pain
Published 2025-02-01“…ABSTRACT Aims This study aimed to identify metabolic markers for diabetic peripheral neuropathic pain (DPNP) in patients with type 2 diabetes mellitus (T2DM). …”
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9226
Ferroptosis triggers mitochondrial fragmentation via Drp1 activation
Published 2025-01-01“…Abstract Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases. …”
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9227
Correlation between daily physical activity and intestinal microbiota in perimenopausal women
Published 2025-05-01“…The results showed perimenopausal women exhibited significantly lower levels of daily physical activity, including Kcals, metabolic equivalents (METs), and moderate-to-vigorous physical activity (MVPA), compared to youth women. …”
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9228
Pathological Features of Mitochondrial Ultrastructure Predict Susceptibility to Post-TIPS Hepatic Encephalopathy
Published 2018-01-01“…Post-TIPS hepatic encephalopathy (PSE) is a complex process involving numerous risk factors; the root cause is unclear, but an elevation of blood ammonia due to portosystemic shunt and metabolic disorders in hepatocytes has been proposed as an important risk factor. …”
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9229
Diffused Multi-scale Generative Adversarial Network for low-dose PET images reconstruction
Published 2025-02-01“…Compared to other methods, the synthesized full-dose PET image generated by our method exhibits a more accurate voxel-wise metabolic intensity distribution, resulting in a clearer depiction of the epilepsy focus. …”
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9230
Impact of garlic polysulfide supplementation on biochemical and hematological parameters in dairy cows
Published 2024-01-01“…The use of different mixtures of biologically active garlic polysulfides in the diet could improve immune and metabolic status, as well as support mastitis treatments in dairy cows.…”
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9231
Challenges and Novelties in the Treatment of Obesity in Adults. A review
Published 2025-01-01“…Additionally, bariatric surgery continues to offer great solution for severe obesity, combining restrictive and malabsorptive mechanisms for significant weight loss and metabolic benefits. The main procedures include gastric bypass with sleeve gastrectomy or duodenal switch. …”
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9232
Relationship between green space near schools with physical activity and body mass index in portuguese adolescents
Published 2023-03-01“…The present investigation does not support the idea that UGS number and the NDVI close to school promote PA and metabolic health in adolescents, as the results proved to be inconsistent and dependent on the distance threshold used to define geographic proximity. …”
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9233
Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis
Published 2017-01-01“…Fibroblast growth factor 21 (FGF21) is an important endocrine metabolic regulator with emerging beneficial roles in lipid homeostasis. …”
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9234
Obesity and Cytokines in Childhood-Onset Systemic Lupus Erythematosus
Published 2014-01-01“…In systemic lupus erythematosus (SLE), atherosclerosis is attributed to traditional and lupus related risk factors, including metabolic syndrome (MetS), obesity, and inflammation. …”
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9235
Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial
Published 2014-01-01“…Secondary endpoints included office blood pressure (BP), early carotid atherosclerosis, arterial stiffness measured by pulse wave velocity (PWV), and metabolic parameters. Results. 51 severe OSA patients were randomized. …”
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9236
Epidemiology of chronic and acute pancreatitis in India (EPICAP-India): protocol for a multicentre study
Published 2024-12-01“…For each case, four controls will be selected and data on risk factors for CP (tobacco, alcohol, family history, metabolic causes) and blood for genetic markers will be collected. …”
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9237
IUPHAR review: Targeted therapies of signaling pathways based on the gut microbiome in autism spectrum disorders: Mechanistic and therapeutic applications
Published 2025-01-01“…In addition, this review discusses the interactions between gut microbiota and the immune, metabolic and neuroendocrine systems, focusing on crucial microbial metabolites including short-chain fatty acids (SCFAs) and several neurotransmitters. …”
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9238
Using ICT Tools for Exploring the Impact of Urban Blue-Green Spaces on Human Health and Well-Being
Published 2024-11-01“…The primary methodological approach of HEART clinical studies across three demonstration cities focuses on understanding how HEART project interventions relate to four chronic disease groups: cardiovascular, respiratory, mental, and metabolic conditions, with healthy participants as the control group. …”
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9239
Cardiometabolic deaths in black and white men: Tracing the risks from early- to mid-adulthood
Published 2025-03-01“…We estimated cumulative risk, excess mortality, years of lost life (YLL), and proportion of deaths due to CMD, stratifying by metabolic and cardiovascular disease. Results: Of the 325,134 Black men aged 25 years in the initial cohort, the cumulative risk of cardiometabolic death before age 45 was one in 63 individuals or 1.58 %. …”
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9240
Liver morphometry and histopathology effects in Astyanax lacustris exposed to lambda-cyhalothrin pyrethroid insecticide
Published 2025-06-01“…Hepatic glycogen storage decreases at 6 and 12 dpe showing metabolic damage. Both, density and volume of decreases after LC exposure in all exposure time. …”
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