Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases by Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, Cristian Papara, David A. De Luca, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, Matthias Laudes, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Ralf J. Ludwig, Ralf J. Ludwig

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Assessment of post-partum physical exercise practice and its associated factors among women in postpartum period, in West Wollega zone, Oromia, Ethiopia by Tegegne Yadeta, Daniel Belema, Seifedin Ahmad, Nurye Sirage, Abubeker Seid Ali, Kedir Ali, Ali Yimer

“…Incorporating regular physical activity during this phase has demonstrated the potential to mitigate the chances of chronic metabolic disorders. Nevertheless, there is a lack of comprehensive understanding regarding women’s engagement in postpartum physical exercise during this time.MethodsThe research employed a community-based cross-sectional study design carried out between April 20 and May 20, 2023. …”
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E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

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Rosiglitazone Induces Mitochondrial Biogenesis in Differentiated Murine 3T3-L1 and C3H/10T1/2 Adipocytes by James X. Rong, Jean-Louis D. Klein, Yang Qiu, Mi Xie, Jennifer H. Johnson, K. Michelle Waters, Vivian Zhang, Jennifer A. Kashatus, Katja S. Remlinger, Nan Bing, Renae M. Crosby, Tymissha K. Jackson, Sam M. Witherspoon, John T. Moore, Terence E. Ryan, Sue D. Neill, Jay C. Strum

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Healthy lifestyle before and during pregnancy to prevent childhood obesity: study protocol for a parallel group randomised trial — the PRE-STORK trial by Tina Vilsbøll, Signe S Torekov, Julie Lyng Forman, Romain Barrès, Andreas Andersen, Filip K Knop, Signe Foghsgaard, Klaus Bønnelykke, Thomas Bergholt, Karoline Kragelund Nielsen, Christina Anne Vinter, Majken Lillholm Pico, Louise Groth Grunnet, Nina Kornerup, Julie Hagstrøm Danielsen, Ronni Eg Sahl, Mette Yun Johansen, Louise Kelstrup, Nida Ghauri, Emilie Grønlund, Lærke Lund

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The Influences of Rootstock on the Performance of Pinot Noir (Vitis vinifera L.): Berry and Wine Composition by Yipeng Chen, Zijian Liang, Mark Krstic, Peter Clingeleffer, Kate Howell, Deli Chen, Pangzhen Zhang

“…Furthermore, the results could guide future studies in understanding the roles of rootstocks in regulating the metabolic pathways of phenolic and volatile production in the berries of grafted Pinot noir at the molecular level.…”
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Effects of Lysophospholipids on the Antioxidant Capacity, Digestive Performance, and Intestinal Microbiota of <i>Litopenaeus vannamei</i> by Hailiang Yan, Yun Wang, Hong Liang, Yafei Duan, Jun Wang, Chuanpeng Zhou, Zhong Huang

“…The functional abundance of the intestinal microbiome was primarily enriched in metabolic pathways. Overall, the incorporation of lysophospholipids into the diet exerted a beneficial effect on the antioxidant capacity, digestive performance, and intestinal microbiota of <i>L. vannamei</i>, especially with the supplementation of 0.1% lysophospholipids.…”
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The Use of Social Network in Daily Pediatric Practice and Education: Turkish Pediatric Atelier by Erdem Gönüllü, Ahmet Soysal, İlkay Can, Ercan Tutak, Turan Tunç, İsmail Yıldız, Osman Yeşilbaş, Naci Öner, Ali Anarat, Feryal Gün Soysal, Cengiz Bayram, Mehmet Cihan Balcı, Emine Betül Tavil, Teoman Akçay, Metin Karaböcüoğlu

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Assessing the feasibility of measuring residents’ quality of life in English care homes and the construct validity and internal consistency of measures completed by staff proxy: a... by Claire Goodman, Julienne Meyer, Karen Spilsbury, Barbara Hanratty, Rachael Carroll, Adam L Gordon, Gizdem Akdur, Anne Killett, Jennifer Burton, Ann-Marie Towers, Stacey Rand, Nick Smith, Sinead Palmer, Stephen Allan, Lucy Anne Webster

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Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis by Beatriz Cicuéndez, Alfonso Mora, Juan Antonio López, Andrea Curtabbi, Javier Pérez-García, Begoña Porteiro, Daniel Jimenez-Blasco, Pedro Latorre-Muro, Paula Vo, Madison Jerome, Beatriz Gómez-Santos, Rafael Romero-Becerra, Magdalena Leiva, Elena Rodríguez, Marta León, Luis Leiva-Vega, Noemi Gómez-Lado, Jorge L. Torres, Lourdes Hernández-Cosido, Pablo Aguiar, Miguel Marcos, Martin Jastroch, Andreas Daiber, Patricia Aspichueta, Juan Pedro Bolaños, Jessica B. Spinelli, Pere Puigserver, José Antonio Enriquez, Jesús Vázquez, Cintia Folgueira, Guadalupe Sabio

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Risk and Prognosis of Hepatocellular Carcinoma in Mexican Americans with Type 2 Diabetes Mellitus by Hatia RI, Hwang LY, Li R, Troisi C, Jalal PK, Amos CI, Gomez HF, Chun YS, Rashid A, Kaseb AO, Scheet PA, Hassan MM

“…Type 2 DM significantly increased the risk of HCC alone and in conjunction with other parameters of metabolic syndrome in the Mexican American population after adjusting for other risk factors.Keywords: diabetes mellitus, Mexican Americans, hepatocellular carcinoma, metformin, interactions…”
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Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice by Tatsuhito Himeno, Hideki Kamiya, Keiko Naruse, Zhao Cheng, Sachiko Ito, Taiga Shibata, Masaki Kondo, Jiro Kato, Tetsuji Okawa, Atsushi Fujiya, Hirohiko Suzuki, Tetsutaro Kito, Yoji Hamada, Yutaka Oiso, Kenichi Isobe, Jiro Nakamura

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Work performance, physiological and hemato-biochemical responses in working buffalo with different load weights by Visoky Paján-Jiménez, Fernando D. Pazmiño-Rodríguez, Patricia Roldán-Santiago, Cristian Larrondo-Cornejo, Anna Dutro-Aceves, Luis A. de la Cruz-Cruz

“…Therefore, it is concluded that heavier loads increase work efficiency but generate greater physiological and metabolic demand. Further studies are needed to understand the long-term effects on the welfare of working buffaloes destined for rural activities. …”
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Functional and Structural Consequences of Nine CYP21A2 Mutations Ranging from Very Mild to Severe Effects by Débora de Paula Michelatto, Leif Karlsson, Ana Letícia Gori Lusa, Camila D’Almeida Mgnani Silva, Linus Joakim Östberg, Bengt Persson, Gil Guerra-Júnior, Sofia Helena Valente de Lemos-Marini, Michela Barbaro, Maricilda Palandi de Mello, Svetlana Lajic

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Status and annual change of vulnerability among middle-aged and elderly people with cardiometabolic multimorbidity in a division of Xinjiang Production and Construction Corps, 2017... by Ziqi WANG, Jieting CHEN, Mei ZHANG, Mingxia JING

“…MethodsStudy data were collected from 839 patients aged ≥ 45 years with cardiovascular metabolic disease (CMD) who participated in a baseline survey in July 2017 and 3 follow-up surveys in July 2018, July 2019, and July 2021 in 3 urban and 2 regimental communities in a division of the Xinjiang Production and Construction Corps. …”
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Cardiomyopathy and kidney function in agalsidase beta‐treated female Fabry patients: a pre‐treatment vs. post‐treatment analysis by Christoph Wanner, Ulla Feldt‐Rasmussen, Ana Jovanovic, Aleš Linhart, Meng Yang, Elvira Ponce, Eva Brand, Dominique P. Germain, Derralynn A. Hughes, John L. Jefferies, Ana Maria Martins, Albina Nowak, Bojan Vujkovac, Frank Weidemann, Michael L. West, Alberto Ortiz

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Sequential use of low-load-blood-flow-restricted vs. high-load resistance training on neuromuscular activation, hypertrophy and neuromuscular performance by Romina Ledergerber, Paul Ritsche, Eric Lichtenstein, Martin Keller

“…The analysis of the remaining participants may help clarify these effects and enlighten, how mechanical tension and metabolic stress contribute to neural adaptations. …”
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Meeting Report on “The International Congress on Autoimmune Pre-disease (2024)” by Justus Ohmes, Afsaneh Mehrpouyan, Julia Wimmer-Groß, Abdul Razzaque Ahmed, Kyle T. Amber, Swayanka Biswas, Angela Christiano, Shirin Emtenani, Stephanie Goletz, Jennifer Elisabeth Hundt, Laura Kirchhoff, Khalaf Kridin, Julie Lasselin, Matthias Laudes, Wing Yu Lee, Ralf J. Ludwig, Sripriya Murthy, Sadegh Mousavi, Tamas Nemeth, Mareike Neumann, Isa Popken, Rochi Saurabh, Alessia Maria Sbaraglia, Jovan Schanzenbacher, Carolin Schmidt, Leon F. Schmidt-Jimènez, Christian Willi Scheiner, Mareile Schlotfeldt, Nora Schoell, Farbod Bahreini, Sarah Stenger

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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Melanoma cells containing an IFN-γ receptor (IFNγR) cytoplasmic domain deletion mutant was overexpressed and used for characterization of the metabolic profile of those tumor cells using a Seahorse Flux Analyzer.Results Met administration elevates mtROS and cell surface Glut-1, resulting in the production of IFN-γ in CD8TILs. mtROS activates Nrf2 in a glycolysis-dependent manner, inducing activation of autophagy, glutaminolysis, mTORC1, and p62/SQSTM1. mTORC1-dependent phosphorylation of p62 at serine 351 (p-p62(S351)) is also involved in activation of Nrf2. …”
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Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome by Nadja Scherbakov, Marvin Szklarski, Jelka Hartwig, Franziska Sotzny, Sebastian Lorenz, Antje Meyer, Patricia Grabowski, Wolfram Doehner, Carmen Scheibenbogen

“…There were no differences between the patient group with ED and the patient group with normal endothelial function regarding demographic, metabolic, and laboratory parameters. Further, there was no difference in soluble vascular cell adhesion molecule and soluble intercellular adhesion molecule levels. …”
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