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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Published 2025-02-01“…Excessive consumption of sucrose, in the form of sugar-sweetened beverages, has been implicated in the pathogenesis of metabolic dysfunction‐associated fatty liver disease (MAFLD) and other related metabolic syndromes. The c-Jun N-terminal kinase (JNK) pathway plays a crucial role in response to dietary stressors, and it was demonstrated that the inhibition of the JNK pathway could potentially be used in the treatment of MAFLD. …”
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642
Effect of Black Cumin on the Expression of Genes Related to Lipid Metabolism in Adipose Tissue: A Mouse Model Study
Published 2024-02-01“…The results of this study are supported by similar studies and confirmed that the compounds in black cumin can be useful in preventing abnormal fat storage and problems such as metabolic syndromes by modulating the cellular metabolism of lipids.…”
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643
Prevalence of dyslipidaemia and transaminitis in obese 8 to 18-year-old in Eastern India
Published 2024-10-01“…Keywords: obesity; childhood; adolescence; lipid profile; dyslipidaemia; NAFLD; metabolic syndrome…”
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644
Impact of Prenatal Stress on Neuroendocrine Programming
Published 2007-01-01“…Such prenatal stress-induced modifications of the phenotypic plasticity of the progeny might ultimately result in the development of long-term diseases, from metabolic syndromes to psychiatric disorders. Yet, we would like to consider the outcome of this neuroendocrine programming from an evolutionary perspective. …”
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645
Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Published 2021-01-01“…Sodium-glucose cotransporter 2 (SGLT2) and dipeptidyl peptidase-4 (DPP-4) inhibitors are glucose-lowering drugs whose anti-inflammatory properties have recently become useful in tackling metabolic syndromes in chronic inflammatory diseases, including diabetes and obesity. …”
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646
Improving Growth Performance, Biochemical Parameters and Reducing Mortality due to Ascites in Broilers by Propranolol Inclusion
Published 2024-12-01“…Introduction: Pulmonary hypertension syndrome (ascites) is one of the most common metabolic syndromes in today's fast-growing broilers. It is associated with rapid growth and is characterized by the accumulation of fluid in the abdominal spaces. …”
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