Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…Our results suggest that Hua-Feng-Dan may mitigate ischemic stroke injury by renormalizing gut microbiota and restoring gut barrier function, gut metabolism, thereby helping to alleviate inflammatory, neurological damage, and brain metabolic disorders.…”
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The Relationship between Simple Snoring and Metabolic Syndrome: A Cross-Sectional Study by Juanjuan Zou, Fan Song, Huajun Xu, Yiqun Fu, Yunyan Xia, Yingjun Qian, Jianyin Zou, Suru Liu, Fang Fang, Lili Meng, Hongliang Yi, Jian Guan, Huaming Zhu, Bin Chen, Shankai Yin

“…Simple snorers showed more severe metabolic disorders and higher prevalence of MetS than nonsnorers. …”
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Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila by Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

“…Conclusion: These findings highlight the potential therapeutic role of CSE in managing obesity and related metabolic disorders.…”
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Maternal exposure to deltamethrin during pregnancy and lactation impairs hippocampal learning and memory function of male offspring by ferroptosis by Shasha Huang, Wanqi Li, Dengke Wang, Huiwen Feng, Bo Wang, Xinyu Dong, Wei Zhao, Dan Liu, Yuan Wang

“…Exposure to DM can lead to iron metabolism disorder, oxidative stress and learning and memory dysfunction. …”
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Gut bacterium Intestinimonas butyriciproducens improves host metabolic health: evidence from cohort and animal intervention studies by Elena Rampanelli, Nadia Romp, Antonio Dario Troise, Jakshana Ananthasabesan, Hao Wu, Ismail Sahin Gül, Sabrina De Pascale, Andrea Scaloni, Fredrik Bäckhed, Vincenzo Fogliano, Max Nieuwdorp, Thi Phuong Nam Bui

“…It is therefore of interest to investigate the causal role of this bacterium and fructoselysine metabolism in metabolic disorders. Results We assessed associations of I. butyriciproducens with metabolic risk biomarkers at both strain and functional levels using a human cohort characterized by fecal metagenomic analysis. …”
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The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows by Zheng Zhou, Kang Yong, Zhengzhong Luo, Zhenlong Du, Tao Zhou, Xiaoping Li, Xueping Yao, Liuhong Shen, Shumin Yu, Yixin Huang, Suizhong Cao

“…Danggui Buxue Tang (DBT), stimulating energy metabolism, ameliorates diseases related to lipid metabolism disorders and is expected to be an effective supplement for alleviating excessive lipid mobilisation in periparturient dairy cows. …”
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Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide pros... by Gaoshu Zheng, Jijie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jianghua Zhou

“…Abstract Background As an emerging concept, Cardiovascular-kidney-metabolic syndrome (CKM) elucidates the intricate interconnection between metabolic disorders(Mets), cardiovascular disease(CVD), and chronic kidney disease(CKD). …”
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Metasilicate-based alkaline mineral water improves the growth performance of weaned piglets by maintaining gut-liver axis homeostasis through microbiota-mediated secondary bile aci... by Jian Chen, Kanwar K. Malhi, Xiaowei Li, Xiangwen Xu, Jianxun Kang, Bichen Zhao, Yaru Xu, Xuenan Li, Jinlong Li

“…Our results indicated that metasilicate-based AMW effectively alleviated weaning-induced colonic or liver morphological injury and inflammatory response, as well as liver cholesterol metabolism disorders. Further analysis showed that metasilicate-based AMW promoted deoxycholic acid (DCA) biosynthesis by increasing the abundance of Lactobacillus_delbrueckii in the colon (P < 0.001). …”
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Targeted Inhibition of GATA-3 by Pyrrothiogatain: Implications for Adipocyte Biology and Inflammatory Response by Shamma Almuraikhy, Maha Alser, Khaled Naja, Aisha Al-Malki, Nayef A. Mazloum, Mohamed A. Elrayess

“…This study provides new insights into the multifaceted actions of Pyrrothiogatain and highlights its potential as a therapeutic agent for lowering inflammation and oxidative-stress-related aspects of metabolic disorders, distinct from the direct modulation of adipogenesis.…”
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Protective and Ameliorative Effects of Hydroethanolic Extract of Piper nigrum (L.) Stem against Antiretroviral Therapy-Induced Hepatotoxicity and Dyslipidemia in Wistar Rats by Doreen Enyang, Mubo A. Sonibare, Armelle D. Tchamgoue, Lauve R. Y. Tchokouaha, Fanta S. Yadang, Gael N. Nfor, Christelle W. Kom, Patrick D. H. Betote, Cedric F. Tchinda, Steveng S. K. Tiogo, Gabriel A. Agbor

“…However, ART-associated hepatotoxicity and metabolic disorders in HIV/AIDS patients are growing concerns to clinicians, especially due to the long-term use of the drugs. …”
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Appetite Suppression and Antiobesity Effect of a Botanical Composition Composed of Morus alba, Yerba mate, and Magnolia officinalis by Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia

“…Here we describe a standardized blend composed of extracts from three medicinal plants: Morus alba, Yerba mate, and Magnolia officinalis for appetite suppression and metabolic disorders management. Method. Extracts were standardized to yield a composition designated as UP601. …”
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Effect of soluble dietary fiber extracted from Lentinula edodes (Berk.) Pegler on lipid metabolism and liver protection in mice on high-fat diet by Kangxiao Guo, Kangxiao Guo, Jing Liu, Zihan Yao, Zhoujin Tan, Tao Yang

“…It is proved that the soluble dietary fiber of Lentinus edodes can alleviate the organ fat accumulation caused by high-fat diet to some extent, effectively combat the liver injury, oxidative stress pressure and lipid metabolism disorder caused by high-fat diet, and provide an experimental basis for the subsequent effective use of soluble dietary fiber of Lentinus edodes in fat reduction.…”
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Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway by Yan Ye, Yan Ye, Xiaopeng Huang, Xiaopeng Huang, Xiaopeng Huang, Xueying Li, Xueying Li, Fei Gao, Wenzhen Zhong, Anqi Tang, Anqi Tang, Liangbin Zhao, Dengpiao Xie, Naijing Ye, Naijing Ye

“…Additionally, our results suggest that SSKE regulates NF-κB pathways, increases the expression of tight junction proteins, improves intestinal permeability, promotes the growth of beneficial bacteria, inhibits the proliferation of harmful bacteria, and reduces metabolic disorders. Ultimately, these effects contribute to the efficacy of SSKE in treating CKD.ConclusionThese results indicate that SSKE restores intestinal barrier function by regulating the microbiota-gut-kidney axis, thereby treating CKD.…”
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The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Op... by Xiaotong Yu, Lipeng Xu, Qiang Zhou, Shengping Wu, Jiaxing Tian, Chunli Piao, Hailong Guo, Jun Zhang, Liping Li, Shentao Wu, Meizhen Guo, Yuzhi Hong, Weirong Pu, Xiyan Zhao, Yang Liu, Bing Pang, Zhiping Peng, Song Wang, Fengmei Lian, Xiaolin Tong

“…Studies have shown an increasing number of type 2 diabetes (T2D) patients with concomitant obesity and hyperlipidemia syndromes, resulting from relevant metabolic disorders. However, there are few medications and therapies, which can thoroughly address these issues. …”
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Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency by Yunting Zhou, Junming Zhou, Yumin Zhang, Jun Tang, Bo Sun, Wei Xu, Xiaohang Wang, Yang Chen, Zilin Sun

“…The underlying mechanisms involved in Vitamin A- (VA-) related changes in glucose metabolic disorders remain unclear. Recent evidence suggests that intestinal microbiota is closely linked to the metabolic syndrome. …”
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Risk of myocardial infarction and heart failure in gout patients: a systematic review and meta-analysis by Panpan Wang, Huanhuan Yang

“…Abstract Background Gout is a metabolic disease caused by decreased blood uric acid excretion and purine metabolism disorders. Long-term and persistent metabolic dysfunction gradually affects other organ functions and is the main factor inducing Myocardial Infarction (MI) and Heart Failure (HF), seriously affecting the health of patients. …”
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Association between vitamin D levels and preserved ratio impaired spirometry: an investigation of mediating roles of systemic inflammation and metabolic indicators by Tong Lin, Shanshan Huang, Fen Zhou, Xingkai Shen, Haiyan Mao

“…PRISm has been associated with various health issues, including an increased risk of metabolic disorders and cardiovascular diseases. Vitamin D, known for its anti-inflammatory, immunomodulatory, and antioxidant properties, may play a role in reducing the risk of PRISm. …”
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Hubungan Resistensi Insulin dengan Gambaran Klinis Sindrom Ovarium Polikistik by Meliza Wahyuni, Eva Decroli, Putri Sri Lasmini

“…<br />Kata Kunci: SOPK, resistensi insulin, gambaran klinis<br /><br />Abstract <br />Polycystic Ovary Syndrome (PCOS) is an endocrine and metabolic disorders that is common in reproductive-aged women. …”
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Urinary interleukin 13 level in steroid sensitive and resistant nephrotic syndrome: a cross-sectional single center study by Behnam Ermian, Noosha Samieefar, Aida Vahidi, Daryoush Fahimi, Niloufar Peirovi, Mohamed Husein Aldokhi, Behnaz Bazargani, Arash Abbasi, Fahimeh Askarian, Mastaneh Moghtaderi

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Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis by Jing Ni, Lirong Ren, Ying Liang, Ying Ma, Hejian Xiong

“…In summary, 0.3 mg/kg SeNPs supplementation can regulate the intestinal microbiota, while 4.5 mg/kg SeNPs and 0.3 mg/kg Na2SeO3 can cause amino acid metabolism disorders. SeNPs showed higher safety than Na2SeO3.…”
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