Torovirus infection in animals: a review by V. А. Mischenko, A. V. Mischenko, T. B. Nikeshina, Yu. V. Brovko, А. I. Kushlubaeva

“…Massive digestive disorders of neonatal calves, clinically manifested as diarrhea causing severe dehydration, toxemia, immunodeficiency and metabolic disorders, induce huge economic losses in animal husbandry. …”
Get full text

Efficacy of fish oil supplementation on metabolic dysfunction-associated steatotic liver disease: a meta-analysis by Like Zhou, Dongmei Sun, Houqiao Bai

“…Fish oil supplementation may also regulate blood lipids and improve glucose metabolism disorders.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/#myprospero, identifier CRD42024513246.…”
Get full text

Inhibition of miR-652-3p Regulates Lipid Metabolism and Inflammatory Cytokine Secretion of Macrophages to Alleviate Atherosclerosis by Improving TP53 Expression by Haiyun Liu, Changpeng Zuo, Lijuan Cao, Naiquan Yang, Tingbo Jiang

“…Knockdown of miR-652-3p reduces foam formation in ox-LDL-treated macrophages. miR-652-3p inhibitor ameliorates cholesterol accumulation and lipid metabolism disorder. miR-652-3p negatively regulated TP53 in atherosclerosis. …”
Get full text

Elevated Serum TNF-α Is Related to Obesity in Type 2 Diabetes Mellitus and Is Associated with Glycemic Control and Insulin Resistance by Hana Alzamil

“…Diabetes and obesity are very common associated metabolic disorders that are linked to chronic inflammation. …”
Get full text

Functional effects of operations for malignant gastric neoplasms: prevention, diagnosis and treatment of post-gastrectomy disorders by A. V. Chaika, V. M. Khomyakov, A. B. Ryabov

“…Three basic groups of disorders are defined: disorders related to impaired organ anatomy; disorders caused by change in anatomical and physiological interrelations and developing as a compensatory response (mostly of functional origin); metabolic disorders. Development of inflammatory and of fibrotic anastomotic strictures and stenoses, erosions and/or ulcers, as well as obstruction caused by intestinal loop in relation or peritoneal adhesions make conservative treatment ineffective that require endoscopic or open surgical approaches: bougieurage, stenting or surgical reconstruction. …”
Get full text

Bovine nebovirus infection (review) by V. A. Mischenko, A. V. Mischenko, T. B. Nikeshina, Yu. V. Brovko, A. I. Kushlubaeva

“…Digestive disorders clinically manifested by diarrhea resulting in apparent dehydration, toxemia, enophthalmos, membrane pathology, immunodeficiency and metabolic disorders are prevalent among neonatal calf diseases in early postnatal period. …”
Get full text

Impact of maternal prenatal stress by glucocorticoids on metabolic and cardiovascular outcomes in their offspring: A systematic scoping review. by Claudia Eberle, Teresa Fasig, Franziska Brüseke, Stefanie Stichling

“…Hence, the maternal hypothalamic-pituitary-adrenotrophic (HPA) axis may be stimulated by various "stress" mechanisms as well as risk factors leading to an adverse in utero environment, e.g. by excess exposure of glucocorticoids, contributing to cardio-metabolic disorders in mothers and their offspring.<h4>Objective</h4>To review the evidence of in utero programming by focusing on the impact of maternal "stress", on adverse cardio-metabolic outcomes on their offspring later in life, by identifying underlying (patho-) physiological mechanisms (1) as well as adverse short and long-term cardio-metabolic outcomes (2).…”
Get full text

Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity by Ahmed Rakib, Mousumi Mandal, Md Abdullah Al Mamun, Sonia Kiran, Nelufar Yasmen, Lexiao Li, Daniel M. Collier, Jianxiong Jiang, Frank Park, Udai P. Singh

“…Taken together, these results suggest that a genetic deficiency of siglec-E plays a key role in inducing AT inflammation by differentially altering M-MDSCs and CD8+CXCR3+ T cell function and adipogenesis by TRAF3 and Akt signaling in AT.ConclusionOur findings strongly suggest that modulation of siglec-E pathways might have a protective effect at least in part against AT inflammation and metabolic disorders.…”
Get full text

Role of sirtuins in epigenetic regulation and aging control by E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov

“…As is expected, the activity of sirtuin proteins affects the manifestation of classic signs of aging in the body, such as cellular senescence, metabolic disorders, mitochondrial dysfunction, genomic instability, and the disruption of epigenetic regulation. …”
Get full text

Identification of Two Novel Mutations of ABCD1 Gene in Pedigrees with X-Linked Adrenoleukodystrophy and Review of the Literature by Bingzi Dong, Wenshan Lv, Lili Xu, Yuhang Zhao, Xiaofang Sun, Zhongchao Wang, Bingfei Cheng, Zhengju Fu, Yangang Wang

“…X-linked adrenoleukodystrophy (ALD) is an inherited peroxisomal metabolism disorder, resulting from the loss-of-function mutation of ATP-binding cassette protein subfamily D1 (ABCD1) gene. …”
Get full text

Hypercysteinemia, A Potential Risk Factor for Central Obesity and Related Disorders in Azores, Portugal by Ana Lima, Rita Ferin, Mafalda Bourbon, José Baptista, M. Leonor Pavão

“…Owing to the nature of this study design, a cause-effect relationship between high plasma Cys levels and central obesity or CAD risk could not be derived, but results strongly suggest that hypercysteinemia is a potential risk factor for metabolic disorders, i.e., obesity and insulin resistance, and CAD in Azores, a hypothesis that asks for confirmation through further large prospective studies.…”
Get full text

Predictive biomarkers for cardiometabolic risk in postmenopausal women: insights into visfatin, adropin, and adiponectin by Anna Maria Cybulska, Daria Schneider-Matyka, Ireneusz Walaszek, Mariusz Panczyk, Dorota Ćwiek, Anna Lubkowska, Elżbieta Grochans, Kamila Rachubińska, Katarzyna Malewicz, Mariusz Chabowski, Mariusz Chabowski

“…BackgroundVisfatin, adropin, and adiponectin are involved in many changes associated with obesity and metabolic disorders, and may be related to metabolic syndrome and cardiovascular disease. …”
Get full text

Prevalence and risk factors of hyperuricaemia in non-obese Chinese: a single-centre cross-sectional study by Chengfu Xu, Jinghua Wang, Xinyu Wang, Yishu Chen, Shenghui Chen, Haoliang Zhai

“…Non-obese participants with hyperuricaemia also showed multiple metabolic disorders. We suggest that clinicians pay attention to serum uric acid level in non-obese patients.…”
Get full text

Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men by Jéssica Guedes, Indira Pla, Aniel Sanchez, Gyorgy Marko-Varga, Gilberto Barbosa Domont, K Barbara Sahlin, Berk Hazir, Aleksander Giwercman, Fábio César Sousa Nogueira, Johan Malm, Yvonne Lundberg Giwercman

“…Conclusions and Clinical Implications: Our findings underlined the FSH effect on extragonadal systems and its connection to metabolic disorders often seen as secondary effects of prostate cancer treatment.…”
Get full text

<i>Weizmannia coagulans</i> BC99 Attenuates Oxidative Stress Induced by Acute Alcoholic Liver Injury via Nrf2/SKN-1 Pathway and Liver Metabolism Regulation by Ying Wu, Cheng Li, Yinyin Gao, Jie Zhang, Yao Dong, Lina Zhao, Yuwan Li, Shaobin Gu

“…Additionally, BC99 treatment elevated glutamate and aspartate levels while reducing glycerate and glucose, which collectively increased glutathione levels and mitigated oxidative stress triggered by glucose metabolism disorders. In C. elegans, BC99 reduced excessive ROS by upregulating <i>Nrf2</i>/<i>skn-1</i>, <i>daf-16</i>, and their downstream antioxidant genes, consequently alleviating the biotoxicity associated with alcohol-induced oxidative damage. …”
Get full text

Gene networks and metabolomic screening analysis revealed specific pathways of amino acid and acylcarnitine profile alterations in blood plasma of patients with Parkinson’s disease... by A. A. Makarova, P. M. Melnikova, A. D. Rogachev, P. S. Demenkov, T. V. Ivanisenko, E. V. Predtechenskaya, S. Y. Karmanov, V. V. Koval, A. G. Pokrovsky, I. N. Lavrik, N. A. Kolchanov, V. A. Ivanisenko

“…To identify potential mechanisms of amino acid and acylcarnitine metabolism disorders in PD and VP, regulatory gene networks were reconstructed using ANDSystem, a cognitive system. …”
Get full text

Impact of Metabolic States on SARS-CoV-2 Vaccine Responses in Mouse Models of Obesity and Diabetes by Olivia A. Smith, Brent Fujimoto, Teri Ann S. Wong, Albert To, Troy Odo, Aquena Ball, Brien K. Haun, Hiromi Muramatsu, Ying K Tam, Norbert Pardi, Axel T. Lehrer

“…By contributing these findings, we support efforts to improve vaccine efficacy in populations affected by metabolic disorders, advancing effective immunization against SARS-CoV-2.…”
Get full text

Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C by Masanori Sato, Koji Miyanishi, Shingo Tanaka, Akira Sakurada, Hiroki Sakamoto, Yutaka Kawano, Kohichi Takada, Masayoshi Kobune, Junji Kato

“…We enrolled 24 patients with CHC and 9 patients with chronic gastritis without Helicobacter pylori infection or an iron metabolism disorder as control participants. An oral iron absorption test (OIAT) was administered which involved a dosage of 100 mg of sodium ferrous citrate. …”
Get full text

New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis by Sameh A. Abdelnour, Walaa M. Essawi, Nasser Ghanem, Ibrahim T. El-Ratel, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Ahmed N. F. Neamat-Allah, Shimaa A. Amer, Simon J. Davies, Ali Ali El-Raghi

“…The transition period is often associated with metabolic disorders in Bubalus bubalis. We examined the potential effect of Aspergillus oryzae (ASG) on blood biochemistry, adaptive immunity, milk yield and composition, dry matter intake, inflammation markers, and oxidative stress in buffalo cows. …”
Get full text

Metabolics-Based Study on the Therapeutic Mechanism Behind the Effect of Shenhuang Plaster Applied to the Shenque Acupoint on Gastrointestinal Motility in POI Mice by Yanan Shi, Chenglei Wu, Ting Liu, Rongyun Wang, Bin Ding, Qiuhua Sun

“…Conclusions: POI mice had obvious intestinal flora disorders and metabolic disorders of amino acids and their derivatives, and there was a significant correlation between differential flora and differential metabolites. …”
Get full text