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  1. 181
    Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome

    Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome by WANG Xueling, WANG Xueling, ZHONG Peiling, ZHONG Peiling, ZHAO Zhipeng

    Published 2025-02-01
    “…Conclusion‍　‍AS significantly improves glycolipid metabolic disorder and reproductive dysfunction in PCOS mice, which may be associated with its suppressing endoplasmic reticulum stress by inhibiting the PERK/eIF2α/ATF4/CHOP pathway. …”
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  2. 182
    Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers

    Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers by Yongjiao Zhang, Yongjiao Zhang, Ao Chen, Ao Chen, Sumei Lu, Dong Liu, Xiaolei Xuan, Xiaofei Lei, Mingwei Zhong, Fei Gao

    Published 2025-02-01
    “…BackgroundObesity, a prevalent metabolic disorder, is linked to perturbations in the balance of gene expression regulation. …”
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  3. 183
    Changing trends in the global burden of polycystic ovarian syndrome-related infertility over the past 30 years: retrospective data analysis of the global burden of disease study 2019

    Changing trends in the global burden of polycystic ovarian syndrome-related infertility over the past 30 years: retrospective data analysis of the global burden of disease study 20... by Ming Huo, Yixiang Wang, Xianbin Yuan, Yue Yuan, Xuehong Zhang

    Published 2025-01-01
    “…Abstract Objectives Polycystic ovary syndrome (PCOS) represents a significant and persistent metabolic disorder, emerging as a leading factor contributing to infertility. …”
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  4. 184
    The Role of Lifestyle in the Prevention and Treatment of Insulin Resistance: A Review of Clinical and Intervention Studies

    The Role of Lifestyle in the Prevention and Treatment of Insulin Resistance: A Review of Clinical and Intervention Studies by Daria Rybak, Olga Krupa, Kinga Furtak, Zofia Martyna Wójcik, Kuba Borys Romańczuk, Szymon Przemysław Stolarczyk, Paulina Dorota Pietrukaniec, Bartosz Omasta, Katarzyna Kamińska-Omasta, Magdalena Agata Czerska

    Published 2025-02-01
    “… Introduction  Insulin resistance (IR) is a metabolic disorder characterized by reduced tissue sensitivity to insulin, resulting in impaired glucose homeostasis. …”
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  5. 185
    Associations of co-exposure to polycyclic aromatic hydrocarbons and vitamin D with early lung dysfunction: Mediating roles of metabolic score-visceral adiposity index

    Associations of co-exposure to polycyclic aromatic hydrocarbons and vitamin D with early lung dysfunction: Mediating roles of metabolic score-visceral adiposity index by Baihao Lin, Wanlu Liu, Hank-Han Wang, Haixia Qian, Xinyu Zhu, Mengya Xu, Yuyu Zheng, Nada Alhazmi, Yansen Bai

    Published 2025-01-01
    “…Methods: Based on the National Health and Nutrition Examination Survey (NHANES) 2007–2012, data on urinary PAH metabolites (ΣOH-PAHs), serum vitamin D metabolite levels [Σ25(OH)D], and pulmonary function tests [forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and FEV1/FVC] from 2189 participants, including 369 subjects with early lung dysfunction, defined as PRISm or airflow obstruction. Multiple metabolic disorder indicators were calculated using biochemical markers. …”
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  6. 186
    Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice

    Landscape analysis of m6A modification reveals the dysfunction of bone metabolism in osteoporosis mice by Lifeng Zheng, Chao Lan, Xinyue Gao, An Zhu, Yaoqing Chen, Jinluan Lin, Sunjie Yan, Ximei Shen

    Published 2025-02-01
    “…Osteoporosis (OP) is a prevalent chronic bone metabolic disorder that affects the elderly population, leading to an increased susceptibility to bone fragility. …”
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  7. 187
    Paracrine activity of Smurf1-silenced mesenchymal stem cells enhances bone regeneration and reduces bone loss in postmenopausal osteoporosis

    Paracrine activity of Smurf1-silenced mesenchymal stem cells enhances bone regeneration and reduces bone loss in postmenopausal osteoporosis by Alberto González-González, Itziar Álvarez-Iglesias, Daniel García-Sánchez, Monica Dotta, Ricardo Reyes, Ana Alfonso-Fernández, Alfonso Bolado-Carrancio, Patricia Díaz-Rodríguez, María Isabel Pérez-Núñez, José Carlos Rodríguez-Rey, Jesús Delgado-Calle, Flor M. Pérez-Campo

    Published 2025-02-01
    “…Abstract Background Osteoporosis (OP), characterized by reduced bone mass and mineral density, is a global metabolic disorder that severely impacts the quality of life in affected individuals. …”
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  8. 188
    Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassipes Hook tubers

    Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

    Published 2025-02-01
    “…Background: Diabetes Mellitus is a chronic metabolic disorder caused by genetic disorders and other factors such as the use of certain medications, pancreatic injury, and autoimmune diseases such as rheumatoid arthritis and high blood pressure. …”
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  9. 189
    Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning

    Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

    Published 2025-01-01
    “…IntroductionType 2 diabetes (T2D) is a complex metabolic disorder with significant global health implications. …”
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  10. 190
    Dietary Se-enrich Cardamine violifolia supplementation decreases lipid deposition and improves antioxidant status in the liver of aging laying hens

    Dietary Se-enrich Cardamine violifolia supplementation decreases lipid deposition and improves antioxidant status in the liver of aging laying hens by Mengke Yan, Xin Cong, Hui Wang, Kun Qin, Yuhui Tang, Xiao Xu, Dan Wang, Shuiyuan Cheng, Yulan Liu, Huiling Zhu

    Published 2025-01-01
    “…Aging-related lipid metabolic disorder is related to oxidative stress. Selenium (Se)-enriched Cardamine violifolia (SEC) is known for its excellent antioxidant function. …”
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  11. 191
    The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome

    The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome by Sydora BC, Wilke MS, Ghosh M, Vine DF

    Published 2025-02-01
    “…Beate C Sydora,1 Michaelann S Wilke,1 Mahua Ghosh,2 Donna F Vine1 1Metabolic and Cardiovascular Disease Laboratory, Faculty of Agricultural, Life & Environmental Sciences, University of Alberta, Edmonton, Canada; 2Department of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, CanadaCorrespondence: Donna F Vine, Metabolic and Cardiovascular Disease Laboratory, Faculty of Agricultural, Life & Environmental Sciences, 4-002H Li ka Shing Centre for Research, 8602 112 Street NW, Edmonton, AB, T6G 2E1, Canada, Tel +1 780 492 4393, Email dvine@ualberta.caPurpose: Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder and is associated with a variety of health disorders. …”
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  12. 192
    Clinical Biochemistry /

    Clinical Biochemistry /

    Published 2017
    Table of Contents: “…Biochemical investigations and quality control / David Cameron -- Automation / Tim James -- Kidney disease / Edmund Lamb -- Hyperuricaemia and gout / Joanne Marsden -- Fluid and electrolyte disorders / Tim James -- Acid-base disorders / David Tierney -- Clinical enzymology and biomarkers / Paul Collinson, Amy Lloyd -- Liver function tests / Roy Sherwood -- Abnormalities of lipid metabolism / Mike France -- Disorders of calcium, phosphate, and magnesium homeostasis / Nessar Ahmed -- Abnormal pituitary function ; Thyroid disease / Garry McDowell -- Diabetes mellitus and hypoglycaemia / Allen Yates, Ian Laing -- Adrenal disease / John Honour -- Reproductive endocrinology / Ian Laing, Julie Thornton -- Biochemical nutrition / Pat Twomey, William Simpson -- Gastrointestinal disorders and malabsorption / Garry McDowell, Gordon Brydon -- Specific protein markers / Gerald Maguire -- Cancer biochemistry and tumour markers / Joanne Adaway, Gilbert Wieringa -- Inherited metabolic disorders and newborn screening / Mary Anne Preece -- Therapeutic drug monitoring / Robin Whelpton, Nigel Brown, Robert Flanagan -- Chemical toxicology / Gwendolen Ayers.…”
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  13. 193
    Clinical Biochemistry ; fundamentals of biomedical science /

    Clinical Biochemistry ; fundamentals of biomedical science /

    Published 2017
    Table of Contents: “…Biochemical investigations and quality control / David Cameron -- Automation / Tim James -- Kidney disease / Edmund Lamb -- Hyperuricaemia and gout / Joanne Marsden -- Fluid and electrolyte disorders / Tim James -- Acid-base disorders / David Tierney -- Clinical enzymology and biomarkers / Paul Collinson, Amy Lloyd -- Liver function tests / Roy Sherwood -- Abnormalities of lipid metabolism / Mike France -- Disorders of calcium, phosphate, and magnesium homeostasis / Nessar Ahmed -- Abnormal pituitary function ; Thyroid disease / Garry McDowell -- Diabetes mellitus and hypoglycaemia / Allen Yates, Ian Laing -- Adrenal disease / John Honour -- Reproductive endocrinology / Ian Laing, Julie Thornton -- Biochemical nutrition / Pat Twomey, William Simpson -- Gastrointestinal disorders and malabsorption / Garry McDowell, Gordon Brydon -- Specific protein markers / Gerald Maguire -- Cancer biochemistry and tumour markers / Joanne Adaway, Gilbert Wieringa -- Inherited metabolic disorders and newborn screening / Mary Anne Preece -- Therapeutic drug monitoring / Robin Whelpton, Nigel Brown, Robert Flanagan -- Chemical toxicology / Gwendolen Ayers.…”
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  14. 194
    Altered Daytime Fluctuation Pattern of Plasminogen Activator Inhibitor 1 in Type 2 Diabetes Patients with Coronary Artery Disease: A Strong Association with Persistently Elevated Plasma Insulin, Increased Insulin Resistance, and Abdominal Obesity

    Altered Daytime Fluctuation Pattern of Plasminogen Activator Inhibitor 1 in Type 2 Diabetes Patients with Coronary Artery Disease: A Strong Association with Persistently Elevated P... by Katarina Lalić, Aleksandra Jotić, Nataša Rajković, Sandra Singh, Ljubica Stošić, Ljiljana Popović, Ljiljana Lukić, Tanja Miličić, Jelena P. Seferović, Marija Maćešić, Jelena Stanarčić, Milorad Čivčić, Iva Kadić, Nebojša M. Lalić

    Published 2015-01-01
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  15. 195
    Growth Patterns in the Irish Pyridoxine Nonresponsive Homocystinuria Population and the Influence of Metabolic Control and Protein Intake

    Growth Patterns in the Irish Pyridoxine Nonresponsive Homocystinuria Population and the Influence of Metabolic Control and Protein Intake by Orla Purcell, Aoife Coughlan, Tim Grant, Jenny McNulty, Anne Clark, Deirdre Deverell, Philip Mayne, Joanne Hughes, Ahmad Monavari, Ina Knerr, Ellen Crushell

    Published 2017-01-01
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  16. 196
    Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation

    Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation by Chengyan Huang, Yuanhui He, Ping Chai, Zongxin Liu, Sirui Su, Yanhui Zhang, Yuelan Luo, Shuiping Fu

    Published 2025-02-01
    “…Notably, antibiotic-induced gut microbiota depletion significantly weakened Orlistat’s effect on improving metabolic disorders. Furthermore, microbiota transplanted from Orlistat-treated mice effectively alleviated lipid metabolic disorders caused by a high-fat diet. …”
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  17. 197
    Impact of coronavirus disease 2019 on medical practice in endocrine and metabolic diseases in Japan: a nationwide surveillance study conducted by the Japan Endocrine Society

    Impact of coronavirus disease 2019 on medical practice in endocrine and metabolic diseases in Japan: a nationwide surveillance study conducted by the Japan Endocrine Society by Katsunori Manaka, Sayaka Kato, Ryuichi Sakamoto, Hajime Yamakage, Tsugumi Uema, Shiori Kawai, Megumi Shibata, Izumi Hiratsuka, Sawako Nakachi, Takeshi Onoue, Takefumi Tsuchiya, Michiaki Fukui, Koshi Hashimoto, Atsushi Suzuki, Noriko Makita, Yoshihiro Ogawa, Hiroshi Arima, Noriko Satoh-Asahara, Hiroaki Masuzaki

    Published 2024-05-01
    “…Conditions related to thyroid diseases, glucose metabolism disorders/diabetes, and hypothalamic-pituitary disorders were particularly prevalent. …”
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  18. 198
    Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway

    Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway by Wei Yu, Wenliang Zha, Zhiqiang Ke, Qing Min, Cairong Li, Huirong Sun, Chao Liu

    Published 2016-01-01
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  19. 199
    Transitioning of protein substitutes in patients with phenylketonuria: a pilot study

    Transitioning of protein substitutes in patients with phenylketonuria: a pilot study by Ozlem Yilmaz Nas, Ozlem Yilmaz Nas, Ozlem Yilmaz Nas, Catherine Ashmore, Sharon Evans, Alex Pinto, Anne Daly, Nurcan Yabanci Ayhan, Anita MacDonald

    Published 2025-01-01
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  20. 200
    Latent Inflammation and Insulin Resistance in Adipose Tissue

    Latent Inflammation and Insulin Resistance in Adipose Tissue by I. S. Stafeev, A. V. Vorotnikov, E. I. Ratner, M. Y. Menshikov, Ye. V. Parfyonova

    Published 2017-01-01
    “…It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. …”
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