Treated Follicular Lymphoma, Recurrent Invasive Pneumococcal Disease, Nonresponsiveness to Vaccination, and a Unique Pneumococcus by Clare Murphy, Donald Inverarity, Claire McGoldrick, Lindsay Mitchell, Pamela Paterson, Louise Thom, Giles Edwards

“…The patient then developed pneumococcal meningitis due to a serotype 35F pneumococcus with a unique Multilocus Sequence Type (ST7004) which was not vaccine preventable. …”
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<i>Vibrio vulnificus</i>—A Review with a Special Focus on Sepsis by Marcello Candelli, Marta Sacco Fernandez, Cristina Triunfo, Andrea Piccioni, Veronica Ojetti, Francesco Franceschi, Giulia Pignataro

“…Rare but severe complications, including pneumonia and meningitis, have also been reported. Treatment typically involves the use of doxycycline in combination with third-generation cephalosporins, although the emergence of multidrug-resistant strains is an escalating concern. …”
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Primary cutaneous gamma–delta T cell lymphoma presenting as a leg ulcer in a kidney transplant recipient on hemodialysis: a case report with a literature review by Yuki Oba, Hiroki Mizuno, Shigekazu Kurihara, Daisuke Ikuma, Masayuki Yamanouchi, Tatsuya Suwabe, Katsuyuki Miki, Kei Kono, Kennichi Ohashi, Aya Nishida, Atsushi Wake, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa

“…Although he decided to undergo amputation of his right leg finally, he died following postoperative cytomegalovirus meningitis. Conclusions This is the first case of PCGD-TCL after kidney transplantation. …”
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Influence of the polysaccharide capsule on virulence and fitness of Klebsiella pneumoniae by Lisa Zierke, Rodi Mourad, Thomas P. Kohler, Mathias Müsken, Sven Hammerschmidt

“…In addition to nosocomial, urinary tract and bloodstream infections or pneumonia hypervirulent strains have a highly mucoid phenotype and can cause soft tissue infections, liver abscesses, and meningitis as well. The CPS is therefore crucial for both escaping detection by the immune system and enhancing the virulence potential.MethodsIn this study, we generated a non-encapsulated mutant (Kpn2146∆wza) to observe how the CPS interferes with K. pneumoniae adhesion, survival in blood, and invasiveness in an experimental infection model.ResultsInfection of A549 lung epithelial cells showed similar adherence levels for the wild-type and non-capsulated strain, while our data showed a moderately higher internalization of Kpn2146Δwza when compared to the wild-type. …”
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The pneumococcal bacteriocin streptococcin B is produced as part of the early competence cascade and promotes intraspecies competition by J. D. Richardson, Emily Guo, Ryan M. Wyllie, Paul Jensen, Suzanne Dawid

“…Given the co-regulation with competence and the phenotypic confirmation of activity, streptococcin B represents a previously unrecognized fratricide effector that gives producing strains an additional advantage over the naturally occurring deleted strains during colonization.IMPORTANCEStreptococcus pneumoniae is a common cause of pneumonia, meningitis, sinusitis, and otitis media. In order to successfully colonize humans, a prerequisite to the development of invasive disease, S. pneumoniae must compete with other bacterial inhabitants of the nasal surface for space and nutrients. …”
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Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba by N. Datta

“…PAM is often misdiagnosed as bacterial meningitis, due to its nonspecific clinical presentation and lack of reliable diagnostic tests. …”
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Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs by Maria E. Cirino, Thainá R. Teixeira, Alessandro M. H. Silva, Ana C. C. Borges, Lucas Fukui-Silva, Luis G. Wagner, Christiane Fernandes, Malachy McCann, André L. S. Santos, Josué de Moraes

“…This study investigates the potential antiparasitic activity of 1,10-phenanthroline-5,6-dione (phendione) and its metal complexes, [Cu(phendione)3](ClO4)2.8H2O and [Ag(phendione)2](ClO4), against Schistosoma mansoni, the causative agent of intestinal schistosomiasis, and Angiostrongylus cantonensis, responsible for eosinophilic meningitis in humans. Additionally, the compounds were tested on Caenorhabditis elegans, a model organism for drug discovery. …”
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Intracranial otogenic complications in adults: new factors that influenced its onset, frequency and nature by Małgorzata Wierzbicka, Michalina Staśkiewicz, Oskar Rosiak, Katarzyna Karmelita-Katulska, Witold Szyfter, Wojciech Gawęcki

“…In COVID period, CVST was more prevalent, with 2 cases (22.2%) presenting solitary CVST, and 3 cases (33.3%) CVST and a simultaneous brain abscess or meningitis. CVST was much more frequent in the COVID period (p < 0.01). …”
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Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides by Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil

“…Coccidioides can infect both immunocompetent and immunocompromised people and can cause a devastating disseminated infection, including meningitis, with 30% mortality despite all currently available treatments. …”
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Carga económica de la enfermedad neumocócica en niños de edad preescolar en el Policlínico Cecilio Ruiz de Zárate Castellón. 2016 by Martha Marrero Araújo, Anai García Fariñas, Ana María Gálvez González

“…Los atendidos en el nivel primario después de un egreso hospitalario tuvieron un costo médico directo medio de 106,96 CUP; en los casos con otitis media aguda fue de 89,83 CUP y para aquellos egresados luego de una meningitis o sepsis fue de 152,63 CUP con el mayor valor de costo medio, mínimo y máximo debido a la prolongación de la atención posterior al egreso. …”
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Concurrent Intracranial and Spinal Subdural Hematoma in a Teenage Athlete: A Case Report of This Rare Entity by Daniel S. Treister, Sara E. Kingston, Gabriel Zada, Manu Singh, Jesse G. A. Jones, Jena N. Mills, Alexander Lerner, Orest B. Boyko, Meng Law, Anandh Rajamohan, Mark S. Shiroishi

“…This was accompanied by severe nausea and vomiting for several days. Viral meningitis was suspected by the primary clinician, and treatment with corticosteroids was initiated. …”
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Private sector delivery of care for maternal and newborn health: trends over a decade in the Indian state of Bihar by G. Anil Kumar, Sibin George, Moutushi Majumder, S. Siva Prasad Dora, Md Akbar, Tanmay Mahapatra, Rakhi Dandona

“…Birth asphyxia was the leading cause of death in 2016 (37.8%) and 2020–2021 (33.9%) followed by preterm delivery and neonatal pneumonia; a statistically significant reduction was seen in meningitis/sepsis between 2016 and 2020–2021 (77.8%; 95% CI = − 145.4 to − 10.1). …”
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Fatal toxoplasmic encephalitis triggered by anti-TNF therapy by Rodrigo A. Montoro, Michael Moran, Katherine A. Overmyer, Andrew Periaccante, Joshua J. Coon, Swapnil Lanjewar, Laura J. Knoll, Rob Striker

“…Lumbar puncture ruled out bacterial or viral meningitis. With continued cognitive decline, magnetic resonance imaging of the head revealed an increased number of lesions with T. gondii-associated ring-enhancing lesions. …”
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Nonimmune Hydrops Fetalis and Early Skeletal Changes in Congenital Syphilis: Case Series and Review of Literature by Kruti N Shah, Shwetal Bhatt, Vaishali Chanpura

“…Clinical significance: Congenital syphilis may present with varied clinical presentations, such as hydrops fetalis, fetal growth restriction, anemia, thrombocytopenia, purpura, hepatosplenomegaly, meningitis, sclerotic bony changes, facial deformities, etc. …”
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Selected Biomarkers Correlate with the Origin and Severity of Sepsis by Michal Holub, Olga Džupová, Michaela Růžková, Alžběta Stráníková, Eva Bartáková, Jan Máca, Jiří Beneš, Heiko Herwald, Ondřej Beran

“…Plasma concentrations of MCP-1, sCD14, IL-6, and IL-10 were significantly higher in patients with community-acquired pneumonia (CAP; n=10) and infective endocarditis (IE; n=11) compared to those with bacterial meningitis (BM; n=18). Next, cortisol levels were higher in IE patients than in those with BM and CAP, and at one time point, cortisol was also higher in patients with gram-negative sepsis when compared to those with gram-positive infections. …”
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Coronavirus Host Genomics Study: South Africa (COVIGen-SA) by Andrew K. May, Heather Seymour, Harriet Etheredge, Heather Maher, Marta C. Nunes, Shabir A. Madhi, Simiso M. Sokhela, W. D. Francois Venter, Neil Martinson, Firdaus Nabeemeeah, Cheryl Cohen, Jocelyn Moyes, Sibongile Walaza, Stefano Tempia, Jackie Kleynhans, Anne von Gottberg, Jeremy Nel, Halima Dawood, Ebrahim Variava, Stephen Tollman, Kathleen Kahn, Kobus Herbst, Emily B. Wong, Caroline T. Tiemessen, Alex van Blydenstein, Lyle Murray, Michelle Venter, June Fabian, Michéle Ramsay

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Individualized autoregulation-guided arterial blood pressure management in neurocritical care by Jonathan R. Gomez, Bhagyashri U. Bhende, Rohan Mathur, L. Fernando Gonzalez, Vishank A. Shah

“…The scope of this review includes (1) a summary of the physiology of CA in healthy adults; (2) a review of the evidence on CA monitoring in healthy individuals; (3) a summary of CA changes and its effect on outcomes in various diseased states including acute ischemic stroke, spontaneous intracranial hemorrhage, aneurysmal subarachnoid hemorrhage, sepsis and meningitis, post-cardiac arrest, hypoxic-ischemic encephalopathy, surgery, and moyamoya disease; and (4) a review of the current evidence on individualized ABP changes in various patient populations.…”
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Association of gross domestic product with equitable access to childhood vaccines in 195 countries: a systematic review and meta-analysis by Kwabena Obeng Duedu, Yakhya Dieye, Andreas Ateke Njoh, Jerome Nyhalah Dinga, Jones Soladoye Akinbobola, Funmilayo Ibitayo Deborah Afolayan, Tesfaye Kassa, David Dazhia Lazarus, Gezahegne Mamo Kassa, Nefefe Tshifhiwa, Mustapha Oumouna

“…Global vaccination coverage for tuberculosis, diphtheria/tetanus/pertussis, hepatitis B, Haemophilus influenzae type b, measles, polio, meningitis and HPV had a significantly higher coverage than COVID-19. …”
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CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review by M. Guerreiro, F. Príncipe, M. J. Teles, S. Fonseca, A. H. Santos, E. Fonseca, P. Gomes, C. Marques, M. Lima

“…The patient failed to respond to gemcitabine and cisplatin-based polychemotherapy, dying three months later with leukemic meningitis and multiple cranial nerves palsies. Conclusions. …”
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The effect of meningococcal vaccines on new generation of systemic inflammatory markers in children by Omer Okuyan, Neval Elgormus, Seyma Dumur, Ugurcan Sayili, Hafize Uzun

“…In this study, in order to support the appropriate use of various MVs in the prevention of meningococcal meningitis (MM), the effects of MVs, especially single-dose and inter-booster administered, on inflammatory parameters in < 5-year-old children were investigated. …”
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