Effects of <i>Lactiplantibacillus plantarum</i> and Fermentation Time on the Quality, Bacterial Community, and Functional Prediction of Silage from <i>Lotus corniculatus</i> L. in... by Yang Wang, Yang Yang, Xiaoyu Yang, Lei Huang, Puchang Wang, Lili Zhao

“…The metabolic pathway analysis revealed that the addition of LP enhanced carbohydrate metabolism and improved the replication and repair, translation, transcription, and membrane transport functions of the bacterial community. …”
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Transcriptomics reveals substance biosynthesis and transport on membranes of Listeria monocytogenes affected by antimicrobial lipopeptide brevilaterin B by Yangliu Liu, Yawei Ning, Zhou Chen, Panpan Han, Tongxin Zhi, Siting Li, Aijin Ma, Yingmin Jia

“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis indicated that brevilaterin B influenced multiple pathways of L. monocytogenes, including peptidoglycan biosynthesis, membrane transport (ATP-binding cassette transports, ion transport), cellular metabolism (amino acid and lipid metabolism), ATP synthesis, and activation of the stress response (quorum sensing and bacterial chemotaxis). …”
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First Report of CTNS Mutations in a Chinese Family with Infantile Cystinosis by Yong-jia Yang, Yuan Hu, Rui Zhao, Xinyu He, Liu Zhao, Ming Tu, Lijun Zhou, Jihong Guo, Linqian Wu, Tantai Zhao, Yi-min Zhu

“…Infantile cystinosis (IC) is a rare autosomal recessive disorder characterized by a defect in the lysosomal-membrane transport protein, cystinosin. It serves as a prototype for lysosomal transport disorders. …”
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Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy by Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang

“…Abstract The cell membrane transport capacity and surface targets of multiple myeloma (MM) cells heavily influence chemotherapy and immunotherapy. …”
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Effects of Cellulase and <i>Lactiplantibacillus plantarum</i> on Chemical Composition, Fermentation Characteristics, and Bacterial Community of <i>Pennisetum giganteum</i> z.x.lin... by Zhili Wu, Xiongfei Zhang, Rongnuo Li, Jingtao Hui, Lu Deng, Inho Kim, Jie Wei, Junhu Yao, Xinjian Lei

“…Compared with CE and LP, LPCE more effectively promoted the transformation of microbial functions, resulting in an upregulated (<i>p</i> < 0.05) carbohydrate metabolism and a downregulated (<i>p</i> < 0.05) membrane transport. In conclusion, cellulase or <i>Lactiplantibacillus plantarum</i> improved the silage quality of <i>Pennisetum giganteum</i> z.x.lin by reducing the fiber content or enhancing LA fermentation, and their combination exhibited a powerful ability to establish a bacterial community dominated by <i>Lactobacillus</i>, which facilitated the production of high-quality silage.…”
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Effect of Swimming on Gut Microbiota and Inflammation in Colorectal Cancer Cells Transplanted Mice by LI Jiapeng, XIE Qiurong, WEN Ying, CHEN Haichun, PENG Jun, SHEN Aling

“…Metabolic pathways enrichment of functional genes in the model group was significantly higher than those in the swimming group in terms of infectious diseases, carbohydrate metabolism, parasitism, membrane transport, exogenous biodegradation and metabolism, drug dependence, immune diseases and other amino acid metabolic pathways (<italic>P</italic>&lt;0.05). …”
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The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart by F. C. Howarth, M. A. Qureshi, P. Jayaprakash, K. Parekh, M. Oz, H. Dobrzynski, T. E. Adrian

“…Compared to control SAN, expression of some genes were downregulated in GK-SAN: gap junction, Gja1 (Cx43), Gja5 (Cx40), Gjc1 (Cx45), and Gjd3 (Cx31.9); cell membrane transport, Trpc1 (TRPC1) and Trpc6 (TRPC6); hyperpolarization-activated cyclic nucleotide-gated channels, Hcn1 (HCN1) and Hcn4 (HCN4); calcium channels, Cacna1d (Cav1.3), Cacna1g (Cav3.1), Cacna1h (Cav3.2), Cacna2d1 (Cavα2δ1), Cacna2d3 (Cavα2δ3), and Cacng4 (Cavγ4); and potassium channels, Kcna2 (Kv1.2), Kcna4 (Kv1.4), Kcna5 (Kv1.5), Kcnb1 (Kv2.1), Kcnd3 (Kv4.3), Kcnj2 (Kir2.1), Kcnk1 (TWIK1), Kcnk5 (K2P5.1), Kcnk6 (TWIK2), and Kcnn2 (SK2) whilst others were upregulated in GK-SAN: Ryr2 (RYR2) and Nppb (BNP). …”
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Strain-specific effect of Streptococcus thermophilus consumption on host physiology by Peng Yu, Yang Jiang, Yuqi Pan, Min Guo, Bo Yang, Xiaoming Liu, Jianxin Zhao, Hao Zhang, Wei Chen

“…Comparative genomic analysis revealed that the four S. thermophilus strains belonged to different branches in the phylogenetic tree, and DYNDL13-4 and DQHXNQ38M61 had more genes involved in carbohydrate metabolism, amino acid metabolism, membrane transport, and signal transduction, which may confer the capacity of nutrient utilization and gastrointestinal adaptation of the strains and be associated with their strong regulation in host. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…MTX primarily affected the processes of protein digestion and absorption, mineral absorption, membrane transport, production of aminoacyl-transfer RNA (tRNA), metabolism of nucleotides, lipids, and amino acids, as well as autophagy. …”
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Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef by Marko Terzin, Steven J. Robbins, Sara C. Bell, Kim-Anh Lê Cao, Renee K. Gruber, Pedro R. Frade, Nicole S. Webster, Yun Kit Yeoh, David G. Bourne, Patrick W. Laffy

“…., Rhodospirillaceae, Burkholderiaceae, Flavobacteriaceae, and Rhodobacteraceae) were enriched in reefs with elevated dissolved organic carbon (DOC) and phytoplankton-derived POM, encoding functional genes related to membrane transport, sugar utilization, and energy metabolism. …”
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Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks by Chen Shaopeng, Cui Changze, Qi Youpeng, Mi Baohong, Zhang Meixian, Jiao Chenyue, Zhu Chune, Wang Xiangyan, Hu Jiang, Hu Jiang, Shi Bingang, Shi Bingang, Ma Xueming, Zhao Zhidong, Zhao Zhidong, Zhang Xiaolan

“…KEGG functional prediction of the microbiota indicated that the dominant functions in the rumen, abomasum, colon, and jejunum were amino acid metabolism, glycan biosynthesis and metabolism, carbohydrate metabolism, and membrane transport, respectively, reflecting the digestive functions of these organs. …”
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Spatial variations in the microbiota: comparative analysis of microbial composition and predicted functions across different intestinal segments and feces in donkeys by Yanwei Wang, Yanwei Wang, Yanwei Wang, Tong Hu, Tong Hu, Kaixuan Liang, Kaixuan Liang, Shinuo Li, Shinuo Li, Qiyue Zhang, Qiyue Zhang, Qiyue Zhang, Wenqiang Li, Honglei Qu, Honglei Qu, Boying Dong, Haihua Zhang, Qiugang Ma, Qiugang Ma, Ru Jia, Shimeng Huang, Shimeng Huang

“…A PICRUSt2 functional prediction analysis indicated that carbohydrate metabolism, prokaryotic cellular communities, antimicrobial drug resistance, immune diseases, membrane transport, signal transduction, and transcription exhibited significant differences among the different intestinal segments. …”
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Modulation Effects of Curcumin on Erythrocyte Ion-Transporter Activity by Prabhakar Singh, Syed Ibrahim Rizvi

“…The observed results corroborate membrane transporters activity with susceptibility of erythrocyte membrane towards oxidative damage. …”
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Hepatocellular Bile Salt Transport: Lessons from Cholestasis by Michael Trauner, Peter Fickert, Rudolf E Stauber

“…This review summarizes the molecular defects in hepatocellular membrane transporters that are associated with hereditary and acquired forms of cholestatic liver disease.…”
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Transcriptomic analysis of molecular mechanisms underlying the biodegradation of organophosphorus pesticide chlorpyrifos by Lactobacillus delbrueckii ssp. bulgaricus in skimmed mil... by Yue Yang, Wenxia Zhou, Lingyu Yang, Yilun Chen, Dongxiao Sun-Waterhouse, Dapeng Li

“…After the strain was cultured for 20 h in the presence of chlorpyrifos, differential expressions of 383 genes were detected, including genes probably implicated during chlorpyrifos degradation such as those related to hydrolase, phosphoesterase, diphosphatase, oxidoreductase, dehydratase, as well as membrane transporters. GC-MS/MS analysis revealed the changes of secondary metabolites in L. bulgaricus during milk fermentation due to chlorpyrifos stress. 6-Methylhexahydro-2H-azepin-2-one, 2,6-dihydroxypyridine and methyl 2-aminooxy-4-methylpentanoate as intermediates, along with the proposed pathways, might be involved in chlorpyrifos biodegradation by L. bulgaricus.…”
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Transport of Alzheimer's associated amyloid-β catalyzed by P-glycoprotein. by James W McCormick, Lauren McCormick, Gang Chen, Pia D Vogel, John G Wise

“…P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer's disease (AD). …”
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Deletion of a Putative GPI-Anchored Protein-Encoding Gene Aog185 Impedes the Growth and Nematode-Trapping Efficiency of Arthrobotrys oligospora by Disrupting Transmembrane Transpor... by Hui Peng, Hengqian Lu, Xinyuan Dong, Xiao Liang, Kangliang Sheng, Jingmin Wang, Xiaowei Kong, Xiangdong Zha, Yongzhong Wang

“…Specifically, knockout of Aog185 disrupted transmembrane transport homeostasis during the phagocytosis, cell autophagy, and oxidative phosphorylation processes, which were associated with the fusion of cells and organelle membranes, transport of ions and substrates, and energy metabolism. …”
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Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia by Yulia Nadar Indrasari, Yetti Hernaningsih, Aryati Aryati, Siprianus Ugroseno Yudho Bintoro, Atika Atika, Rosline Hassan

“…P-glycoprotein (Pgp) is the membrane transporter encoded by the multidrug resistance (MDR1) gene, which is responsible for the efflux of several chemotherapeutic drugs for the treatment of AML. …”
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Phosphorylation of Arabidopsis NRT1.1 regulates plant stomatal aperture and drought resistance in low nitrate condition by Yuchen Kou, Bodan Su, Shunyao Yang, Wei Gong, Xi Zhang, Xiaoyi Shan

“…This finding identified a novel drought resistance mechanism enabled by post-transcriptional regulation of plasma membrane transporter.…”
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SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer by Yuqian Yan, Lei Shi, Tao Ma, Liguo Wang, Haojie Huang

“…(1) Background: Prostate cancer treatment efficacy is significantly influenced by androgen receptor (AR) signaling pathways. SLC22A3, a membrane transporter, has been linked to SNP rs9364554 risk loci for drug efficacy in prostate cancer. (2) Methods: We examined the location of SNP rs9364554 in the genome and utilized TCGA and other publicly available datasets to analyze the association of this SNP with <i>SLC22A3</i> transcription levels. …”
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