Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis by Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C

“…Biao Xu,1,* Changshui Wang,2,* Xiaodong Zhu,2 Li Zhu,3 Guangkui Han,2 Changmeng Cui2 1Clinical Medical School, Jining Medical University, Jining, 272067, People’s Republic of China; 2Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, 272000, People’s Republic of China; 3Translational Pharmaceutical Laboratory, Jining No. 1 People’s Hospital, Shandong First Medical University, Jining, 272000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Changmeng Cui; Guangkui Han, Department of Neurosurgery, Affiliated Hospital of Jining Medical University, 89 Guhuai Road, Jining, Shandong, 272000, People’s Republic of China, Tel +86 0537 2908518, Email cmcuidr1989@163.com; guangkui_han@163.comBackground: Corilagin is widely distributed in various medicinal plants. In recent years, numerous pharmacological activities of Corilagin have been reported, including anti-inflammatory, antiviral, hepatoprotective, anti-tumor, and anti-fibrosis effects. …”
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A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant by Pritam Sarkar, Tasfiya Rufaidah Ahnaf, Razina Rouf, Jamil Ahmad Shilpi, Shaikh Jamal Uddin

“…The various parts of this plant have been used in traditional medicinal systems for their potential therapeutic effects in conditions such as asthma, microbial infections, diabetes, pain relief, inflammation, cancer, and arthritis. …”
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Effect of 5-Aminolevulinic Acid on the Quality and Volatile Metabolites of Korla Fragrant Pear Fruit by SUN Tianyu, WEN Bo, WANG Chunfeng, TIAN Jia, HAO Zhichao, LIN Yan, WEN Yue, ZHANG Feng

“…Among them, α-farnesene, 4-[((1E)-1,5-dimethyl-1,4-hexanedi-1-yl]-1-methyl-cyclohexene, δ-cadinene, (E)-1-methyl-4-(6-methylhept-5-en-2-ylidene) cyclohex-1-ene and germacrene B were annotated as key compounds to this pathway, which together endowed Korla fragrant pears with special citrus-like, lavender, lemony, astringent, thyme-like, spicy, earthy, non-medicinal and orange flower-like flavors. In conclusion, it is demonstrated that the exogenous application of 5-ALA significantly improved the quality of Korla fragrant pear fruit, the effect being most pronounced at 5-ALA concentration of 150 mg/L.…”
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Anti-breast cancer activity of some novel quinoline derivatives by Ghorab Mostafa M., Alsaid Mansour S.

“…To discover new bioactive lead compounds for medicinal purposes, 2-cyano-3-(4-substituted)-N-(quinolin-3-yl) acrylamide derivatives 2–24, chromenes 25, 26 and benzochromenes 27, 28 were synthesized. …”
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Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…Background: Traditional medicines remain integral to healthcare worldwide especially in developing countries. …”
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Severe subcutaneous infection with Clostridium septicum in a herd of native Icelandic horses by Charlotta Oddsdóttir, Ólöf G. Sigurðardóttir, Vala Friðriksdóttir, Vilhjálmur Svansson, Birkir Þór Bragason, Sigríður Björnsdóttir

“…Clostridial infections of equine muscle or subcutis following injection with medicinal products have been described in other countries but have never been reported in Iceland. …”
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Multicentre adaptive randomised trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin versus calcineurin inhibitor-based or sirolimu... by Simon Gates, Matthew Collin, Victoria Potter, Rebecca Bishop, Ronjon Chakraverty, Kavita Raj, Adrian Bloor, Andrea Hodgkinson, Jeff Davies, Emma Kempshall, Fiona Dignan, Ram Malladi, Siobhan Smith, Charlotte Gaskell, Gabrielle Smith

“…Secondary outcomes include cumulative incidence of acute grade II-IV GvHD at 1 year, cumulative incidence of moderate and severe chronic GvHD at 1 year, overall survival at 1 year and cumulative incidence of non-relapse mortality at 1 year.Ethics and dissemination The protocol was approved by the West Midlands, Edgbaston Research Ethics Committee (20/WM/0195); initial approval was received on 11 September 2020, current protocol version (V.4.0) approval on 25 July 2023. The Medicines and Healthcare products Regulatory Authority also approved all protocol versions. …”
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Comparison of Antioxidant Properties of Fruit from Some Cultivated Varieties and Hybrids of <i>Rubus idaeus</i> and <i>Rubus occidentalis</i> by Natalia Adamczuk, Mirosława Krauze-Baranowska, Justyna Ośko, Małgorzata Grembecka, Piotr Migas

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Synthesis and Characterisation of a Monolithic Imprinted Column Using a Methacrylic Acid Monomer with Porogen Propanol for Atenolol Analysis by Aliya Nur Hasanah, Firdha Senja Maelaningsih, Fadli Apriliandi, Akhmad Sabarudin

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Forsythia suspensa leaf fermented tea extracts attenuated oxidative stress in mice via the Ref-1/HIF-1α signal pathway and modulation of gut microbiota by Lijuan Li, Yating zhao, Yuxin Ding, Lanze Guo, Ruiyao Dai, Aixiang Chen, Guofeng Duan

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Restoration of Sestrin 3 Expression Mitigates Cardiac Oxidative Damage in Ischemia–Reperfusion Injury Model by Mina Park, Sunghye Cho, Dongtak Jeong

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Crystal structure of 3,5–di-O-benzoyl-1,2-O-isopropylidene-α–D-ribose, C22H22O7 by Wu Binbin, Chen Guangying, Ding Haixin

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Crystal structure of 3-(4-bromophenyl)-5-methyl-1H-pyrazole, C10H9BrN2 by Kočović David, Mugoša Snežana, Shova Sergiu, Tomić Zoran D., Jaćimović Željko K.

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Synthesis and In Vitro Antibacterial Activity of New 2-(1-Methyl-4-nitro-1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles by Bahram Letafat, Negar Mohammadhosseini, Ali Asadipour, Alireza Foroumadi

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New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.) by Resmi Mustarichie, Aliya Nur Hasanah, Gofarana Wilar, Dolih Gozali, Nyi Mekar Saptarini

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YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates by Inés Bouzón-Arnáiz, Mukul Rawat, Rachael Coyle, Lionel Brice Feufack-Donfack, Malen Ea, Agnes Orban, Jean Popovici, Lucía Román-Álamo, Antonino Nicolò Fallica, Bárbara Domínguez-Asenjo, Javier Moreno, Elsa M. Arce, Ana Mallo-Abreu, Diego Muñoz-Torrero, Marcus C. S. Lee, Xavier Fernàndez-Busquets

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Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production by Parnian Arafi, Sujan Devkota, Emily Williams, Masato Maesako, Michael S Wolfe

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Evaluation of the rainfed and irrigated conditions on biomass and essential oil yield of German chamomile (Matricaria chamomilla) in response to melatonin foliar application by Hossein Gorgini Shabankareh, Mohammad Reza Asgharipour, Ali Salehi Sardoei, Ahmad Reza Kamaliun, Hamid Mohammadi, Mansour Ghorbanpour

“…Abstract German chamomile (Matricaria chamomilla L.) is a valuable medicinal plant known for its rich content of bioactive compounds, including chamazulene, α-bisabolol, and α-bisabololoxide A. …”
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Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, follo... by G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero

“…Brexucabtagene autoleucel, a US Food and Drug and European Medicines Agency-approved anti-CD19 chimeric antigen receptor T-cell therapy, marks a significant breakthrough offering hope in this challenging scenario. …”
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Using the WHO building blocks to examine cross-border public health surveillance in MENA by Laura Buback, Shayanne Martin, Esbeydy Pardo, Farah Massoud, Jesus Formigo, Atousa Bonyani, Noha H. Farag, Zayid K. Almayahi, Kenta Ishii, Susie Welty, Dana Schneider

“…Recommendations emphasize strengthened governance and leadership to facilitate regional cooperation and information sharing, sustainable financing for implementing a One Health approach, utilizing innovative information systems, workforce development to enhance data collection and analysis, and secure supply chains for medicines and vaccines and equitable service delivery for all mobile populations. …”
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