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361
Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set...
Published 2025-01-01“…Several potential candidates that mitigate DEHP-mediated cellular apoptosis have been screened out, including quercetin, taurine, methionine, and phloridzin. …”
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362
Autophagy-lysosome pathway in insulin & glucagon homeostasis
Published 2025-02-01“…In this review, we will discuss recent advances in understanding lysosome-mediated autophagy and lysosomal proteins involved in maintaining insulin and glucagon homeostasis, as well as their contributions to the etiology of diabetes.…”
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363
Resilient religion: What good is religion for?
Published 2023-12-01“…The author analyses three mediating processes of resilience that promote the possibility of a synthesis: the recognition of contingency, the experience of fulfilling happiness, and the wonder of possibilisation (new beginnings). …”
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364
Digital economy, green finance, and economic resilience.
Published 2025-01-01“…The development of the digital economy can effectively promote economic resilience, and green finance plays a significant mediating role between the digital economy and economic resilience. …”
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365
Feedback strategies in distance education: a survey of university students
Published 2023-12-01“…Screen-mediated teaching at the university level has necessitated a redesign of learning environments across various dimensions, encompassing epistemological, relational, and pragmatic aspects. …”
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366
Calvin and other religions
Published 2004-06-01“…In this article his views on true and false religion, non-Christian faiths, the uniqueness of Christ as Mediator and Redeemer, and universalism is discussed from the perspective not only of his Institutes, but also of his Commentaries, Tracts and Treatises and Letters. …”
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367
Surviving a crisis: A multilevel model of leadership styles, employees' psychological capital and organizational resilience.
Published 2025-01-01“…The results show that both transformational and directive leadership styles were significant and positive predictors of organizational resilience through the mediating role of employees' psychological capital. …”
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368
Experimental methods of portal hypertension studying
Published 2010-04-01“…Ex vivo studies gave physiological characteristic to the mediators causing splanchnic vasodilation and increasing of vascular tension in cirrhotic liver, and methods of molecular biology identified defects in signalling routes responsible for disorders of metabolism of these substances.Conclusion. …”
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369
Targeted intervention of tumor microenvironment with HDAC inhibitors and their combination therapy strategies
Published 2025-02-01“…Furthermore, the tumor microenvironment, which is intricately linked to cancer development, acts as a mediator in the proliferation of numerous cancers and presents a viable target for oncological therapies. …”
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370
Strongly interacting dark sectors in the early Universe and at the LHC through a simplified portal
Published 2020-01-01“…Abstract We study the cosmology and LHC phenomenology of a consistent strongly interacting dark sector coupled to Standard Model particles through a generic vector mediator. We lay out the requirements for the model to be cosmologically viable, identify annihilations into dark vector mesons as the dominant dark matter freeze-out process and discuss bounds from direct detection. …”
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371
Ferroptosis: mechanism and role in diabetes-related cardiovascular diseases
Published 2025-02-01“…Further study on ferroptosis-mediated cardiac injury can enhance our understanding of the pathophysiology of diabetic cardiovascular diseases and provide more potential therapeutic choices.…”
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372
Obecność i działanie Ducha Świętego w Eucharystii a postawy duchowe kapłana i wiernych
Published 2020-10-01“…Artykuł ukazuje najpierw brak wyraźnych odniesień do Ducha Świętego w przedsoborowej liturgii i w encyklice Mediator Dei Piusa XII (1947). Doceniając odnowę liturgiczną, rozpatruje Konstytucję Sacrosanctum Concilium i wskazuje na pneumatologiczne granice owej konstytucji. …”
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373
Maternal exposure to deltamethrin during pregnancy and lactation impairs hippocampal learning and memory function of male offspring by ferroptosis
Published 2025-01-01“…Thus, maternal exposure to DM during pregnancy and lactation could impair hippocampal learning and memory function of male offspring by p53-mediated ferroptosis.…”
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374
SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell lines
Published 2025-02-01“…This study aimed to investigate whether SHP2 is involved in the P4-mediated cSrc activation in breast cancer cells.MethodsT47D, MCF-7 and BT-483 breast cancer cell lines were used in this study. …”
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375
GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia
Published 2025-02-01“…The changes in angiogenesis markers, autophagy markers, and eNOS levels were detected using qPCR and Western blotting. 3-MA was used to assess the role of autophagy in the activation of eNOS mediated by AST and its subsequent angiogenic effects.Results: GelMA@LNP/AST significantly promoted blood flow recovery in mice with hind limb ischemia. …”
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376
A minimally invasive animal model of atherosclerosis and neointimal hyperplasia for translational research
Published 2025-02-01“…Methods Endothelial denudation was performed via a minimally invasive approach through the auricular artery, followed by stent-retriever mediated endothelial injury in New Zealand White rabbits (n = 10). …”
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377
Co-Creating Knowledge Online: Approaches for Community Artists
Published 2013-12-01“…Forming peer alliances to share and build knowledge is an important aspect of community arts practice, and these co-creation processes are increasingly being mediated by the Internet. This paper offers guidance for practitioners who are interested in better utilising the Internet The decision not to capitalise the word ‘internet’ in this paper is based on the consideration that digital networks that use the Internet protocol suite, TCP/IP, have become ubiquitous means of sending and receiving communications. to connect, share, and make new knowledge. …”
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378
THE CONUNDRUM FACING CHRISTIAN TRADITIONAL LEADERS
Published 2019-12-01“…Given the statement “For there is only one God and one mediator between God and men, the man Christ Jesus” (1 Tim. 2:5), the question is: Where does this place traditions, customs and culture? …”
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379
Signal and modulating role of enzymes of digestive glands
Published 2011-03-01“…Proteinases realize effects through protease-activated receptors of four types which are localized on membranes of glandular cells, leiomyocytes, sensory terminals of afferent neurons and neuroendocrine producers of regulatory peptides, yielding direct and mediated morphofunctional effects.Conclusion. Enzymergic regulation of visceral functions, including sensory, alimentiry, protective, acts as new section of up-to-date science and, according to accumulated facts, is promising in gastroenterology, pancreatology, oncology, immunology and other segments of clinical medicine.…”
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380
Understanding Nitrogen Availability from Applications of Anaerobically Digested Beef-Cattle Manure in Florida Sandy Soil
Published 2015-05-01“… Anaerobic digestion of livestock manure is a microbe-mediated process carried out in vessels or tanks, where the livestock wastes are digested slowly in environment absent of oxygen. …”
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