Unveiling Hidden Aspects of Intermediary Organizations in Innovation: A Systematic Review through the Lens of Industry Taxonomy by Mostafa Mohseni kiasari, ‌Javad Soltanzadeh, Amirhossein Azizi Hasanabadi, Hamed Talebi

“…Since the scope of this study includes the relationship between the functions of mediating institutions and innovation; the two concepts of "intermediary institutions" and "innovation" were defined as the main keywords, and a wide range of synonym keywords were used to collect studies and do a comprehensive search. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…Finally, we established that the suppression of NET formation by S100A8/A9 inhibition is primarily mediated through the AMPK/Nrf2/HO-1 signaling pathway. …”
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β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…Finally, it was demonstrated that ITGB2 mediates these effects mainly through its interaction with intercellular adhesion molecule-1 (ICAM 1) of endotheliocyte. …”
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Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications by Ahmad Vafaeian, Fateme Rajabi, Nima Rezaei

“…TLRs play a crucial role in delaying barrier repair, promoting Th2-mediated dermatitis, shifting the response toward Th1 in the chronic phase, and contributing to the establishment of the itch-scratch cycle, as well as mediating the effects of UV radiation. …”
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Using insecticidal compounds to elucidate the potential role of neurotransmitters in Lepidoptera pupal ecdysis by Niranjana Krishnan, Cassandra Gorman, Jillian Stewart, Steven Bradbury, Russell Jurenka

“…These findings, along with toxicokinetic analyses, suggest that pupal ecdysis may be mediated by the α1, β1, and β2 subunits of nAChRs without involvement of mAChRs. …”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…Abstract Alzheimer’s disease (AD) is characterized by oxidative stress-mediated memory dysfunction and neuronal cell death. …”
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Antisecretory factor in severe traumatic brain injury (AFISTBI): protocol for an exploratory randomized placebo-controlled trial by Linus Réen, David Cederberg, Niklas Marklund, Edward Visse, Peter Siesjö

“…Secondary outcomes will be inflammatory mediators in plasma and intracerebral microdialysis perfusate days 1, 3, and 5 during trial treatment. …”
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NMR probing of copper–amyloid β1–16 interactions and self-assembly by Punnepalli Sunanda, Srinivasarao Raghothama, Uma Maheswari Devi Palempalli, Bankala Krishnarjuna

“… Trace metal ions, such as copper, play an important role in the development of amyloid β (Aβ)-mediated Alzheimer’s disease (AD). Atomic-level investigation of Aβ interaction with copper ions is essential for understanding the metal-mediated peptide self-assembly. …”
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Consumer Anthropomorphism and Happiness: Analysis of the Brand Authenticity Effect by Mehdi Khademi Gerashi, Setare Mohammadian

“…One of the noteworthy findings is that brand authenticity serves as a mediator, effectively explaining how brand anthropomorphism influences consumer happiness. …”
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Pathways Through Which Green Exposure Type Influences Cardiovascular Diseases Mortality in Shanghai, China by Jianzhong HUANG, Yanting XU, Lan WANG, Zhouqian HE

“…The model incorporates three key mediating factors: Air pollution (measured by PM2.5 concentration), extreme high temperature, and physical activity level. …”
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Bridging imagination and strategy in SMEs: The role of ideas and strategy in SME performance by Adin Gustina, Jane S. Liu, Setyabudi Indartono, Nindya N. Laili

“…Furthermore, strategic flexibility mediates the impact of imaginativeness on SME performance, whereas intra-organisational knowledge sharing and resources moderate the impact of imaginativeness on SME performance. …”
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Exploring the necessity of corporate dynamic capability and sustainable performance by Li Mingxing, Ma Zhiqiang, Bailin Ge, Song Xinping, Mohammad Heydari, Maulid H. Bwabo

“…It also provides empirical evidence of agility’s complementary role in mediating the effects of knowledge sharing, sensing capability, and managerial cognitive capability on sustainable performance.…”
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Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

“…In this study, we identify the core genes promoting transcription and expression following T2943-mediated upregulation of H3K14ac, highlighting Grid1 (GluD1) as a central gene. …”
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Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes by Ravi Bhushan, Rimjhim Trivedi, Ritu Raj, Anjali Rani, Sangeeta Rai, Anima Tripathi, Shiv Govind Rawat, Ajay Kumar, Dinesh Kumar, Pawan K. Dubey

“…High-throughput RNA sequencing and computational bioinformatics analyses were conducted to identify novel hub genes, and their regulatory mechanisms were validated through qRT-PCR, western blot, and siRNA-mediated knockdown studies. Intermediate metabolites and circulatory levels of amino acids in the serum of GDM patients and healthy controls were measured. …”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Bufalin has a therapeutic effect on both metastasis and drug resistance, but how bufalin affects chemoresistance-mediated metastasis remains unclear. Methods The role of BU in the inhibition of EMT and angiogenesis induced by chemoresistant cells using wound healing assays, invasion assays, HUVEC tube formation and adhesion assays. …”
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The role of the interleukin family in liver fibrosis by Zixin Zhang, Zixin Zhang, Jiahui Wang, Hui Li, Qun Niu, Qun Niu, Yujing Tao, Yujing Tao, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Haijian Dong, Haijian Dong

“…In this paper, we systematically summarize recent literature to elucidate the pathogenesis of interleukin-mediated liver fibrosis and explore potential therapeutic targets for liver fibrosis treatment.…”
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Research on guest comfort and satisfaction with indoor environmental quality in former GBI-certified green hotels: a study case from Malaysia by Hayder Saadoon Abdulaali, Hayder Saadoon Abdulaali, Ismar M. S. Usman, Mohsen Alawi, Shagea Alqawzai

“…The research evaluates IEQ performance, suggests additional parameters, and explores how comfort mediates the relationship between IEQ and satisfaction. …”
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Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

“…A high concentration of free α-defensins induced NTHi adherence to MDMs but decreased IgG-mediated phagocytosis by MDMs. The decreased phagocytosis was associated with TLR4 activation, downstream signaling via NF-κB p65 and marked increased secretion of inflammatory cytokines, CXCL8, IL-1b, and TNFα by the α-defensin-treated and NTHi-infected MDMs. …”
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Evaluation of the relationship between adversity quotient, professional identity, and perceived humanistic care of head nurses in Master’s Degrees in nursings by Cai Haina, Gu Lingna, He Qingqing, Wang Yang, Cai Zejun, Tian Chuan, Xu Qinghong

“…Adversity quotient (r = 0.430, P < 0.01), perceived humanistic care of nurse leaders (r = 0.443, P < 0.01) and occupational identity were positively correlated, and perceived humanistic care of nurse leaders could affect occupational identity through the mediating effect of adversity quotient, with the mediating effect accounting for 31.8%. …”
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T cell immune senescence is associated with frailty and sarcopenia in lung transplant candidates by Joanna M. Schaenman, MD, PhD, Harry Pickering, PhD, Elaine F. Reed, PhD, Maura Rossetti, PhD, Benjamin Seligman, MD, S. Samuel Weigt, MD, Michael Shino, MD, David Sayah, MD, PhD, John Belperio, MD, Ashley Hu, MD, Ashley Prosper, MD, Kathleen Ruchalski, MD, Abbas Ardehali, MD, Reshma Biniwale, MD

“…Conclusions: These findings suggest that impaired cell-mediated immunity may underlie the associations between frailty and sarcopenia and poor clinical outcomes. …”
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