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31801
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31802
Information Communication Technology and Service Delivery in Nyagatare District Local Goverment, Rwanda.
Published 2020“…The study further concluded that Nyagatare District Local Government should fundraise for ICT donations in terms of training facilitation fees, CT equipment such as computers, to help the members of staff, administration and other stake holders to acquire the necessary skills and equipment for better service delivery in the study area and that there should be favorable government policy that boosts the moral of the private and public investors into ICT business so that there is visible ICT operations in the study area for effective service delivery among other suggested intervention mechanisms to boost ICT for effective service delivery. …”
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31803
The association between physician sex and patient outcomes: a systematic review and meta-analysis
Published 2025-01-01“…Further work is necessary to examine these effects in other care contexts across different countries and understand underlying mechanisms and long-term outcomes to optimize health outcomes for all patients. …”
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31804
Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality
Published 2022-06-01“…Patients in the norepinephrine group required more mechanical ventilation (84% vs. 67%, OR 2.67, 95% CI 1.70–4.25, P < 0.001) and experienced longer ICU stays (median 7 vs. 4 days, OR 7.92, 95% CI 1.40–44.83, P = 0.020) than non‐norepinephrine group. …”
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31805
Exploration of neurometabolic alterations in adolescent patients with bipolar depression and non-suicidal self-injury based on proton magnetic resonance spectroscopy
Published 2025-01-01“…However, the neuropathophysiological mechanisms behind NSSI in ABD remain unclear. Therefore, this study employed proton magnetic resonance spectroscopy (1H-MRS) technology to investigate the potential relationship between NSSI and neurometabolism in the ventromedial prefrontal cortex (vmPFC) of patients with ABD.MethodsThis study compared brain biochemical metabolism between ABD with and without NSSI. …”
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31806
Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study
Published 2025-02-01“…Intervention consisted of steps 1 (oral hygiene instructions and professional mechanical plaque removal) and 2 (subgingival instrumentation) of periodontal therapy, including an antiseptic mouth rinse for 7 days. …”
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31807
Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization
Published 2025-02-01“…Objective: To explore the molecular mechanism by which ginseng-derived nanoparticles (GDNPs) inhibit the growth of human non-small cell lung cancer cells (A549) by altering the polarization state of macrophages. …”
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31808
Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User
Published 2025-01-01“…On this foundation, we derive closed-form expressions for the average block-error rate (BLER) to analyze the performance of trustworthy users as well as the average secure BLER to quantify the secure performance when untrustworthy users wiretap trustworthy users’ information using successive interference mechanisms. Moreover, we further develop asymptotic expressions for both cases to measure the diversity gain and induce key parameters. …”
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31809
Dietary Solid-state-fermentation product of Bacillus velezensis T23 alleviate hepatic steatosis, oxidative stress, gut barrier damage, and microbiota dysbiosis in juvenile genetica...
Published 2025-03-01“…The application of commensal probiotic bacteria is one of the preferable green feed additives for antibiotic substitution in aquaculture, while the application methods and detailed action mechanisms of commensal bacteria isolated from aquatic animals are not consistent with normal mammalian-derived probiotics. …”
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31810
The anticancer properties, cell-cycle cytotoxicity and apoptosis of cissus rotundifolia, trema orientalis, and buddleja polystachya with ocular applications
Published 2025-02-01“…The detected phytoconstituents in the plant extract might be involved in the tested cytotoxic activity and its molecular apoptotic mechanism. Future studies are required to isolate the active ingredient(s) and confirm the therapeutic application(s).…”
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31811
Free fatty acids may regulate the expression of 11β-hydroxysteroid dehydrogenase type 1 in the liver of high-fat diet golden hamsters through the ERS-CHOP-C/EBPα signaling pathway...
Published 2025-02-01“…Abstract Objective Free fatty acids (FFA) can increase the expression of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) in local tissues and organs. However, the mechanism underlying the effect of FFA on 11β-HSD1 expression remains unclear. …”
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31812
The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient...
Published 2025-01-01“…MetS was found to be an independent factor of impaired MEEI and LV GLPS, the further decrease of MEEI and LV GLPS in INOCA patients caused by MetS might involve the synergistic injury mechanism. Early diagnosis and treatment of MetS in patients with INOCA are important.…”
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31813
Targeting deubiquitinase USP7-mediated stabilization of XPO1 contributes to the anti-myeloma effects of selinexor
Published 2025-01-01“…Nevertheless, in myeloma, the precise mechanisms underlying SEL-induced XPO1 degradation and its impact on drug responsiveness remain largely undefined. …”
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31814
Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series
Published 2024-04-01“…Two patients required mechanical ventilation, and 2 received acute dialysis. …”
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31815
The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e...
Published 2025-12-01“…This study aims to detect if MBD2 can reduce NETs formation and the potential mechanism in severe asthma.Methods A severe asthma model was established in C57BL/6 wild-type mice exposure to house dust mite (HDM), ovalbumin (OVA), and lipopolysaccharide (LPS). …”
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31816
Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral...
Published 2025-03-01“…Despite similar radiographic findings, mechanical performance and histological structure displayed in both grafted groups, AOPT exhibit superior interface integration, which is critical for effective tissue restoration. …”
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31817
Non Linear Thermal Radiation Analysis of Electromagnetic Chemically Reacting Ternary Nanofluid Flow over a Bilinear Stretching Surface
Published 2025-03-01“…Motivation: The increasing demand for advanced heat transfer mechanisms has driven interest in hybrid and ternary nanofluids due to their superior thermal properties compared to conventional fluids. …”
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31818
First report of serological, molecular detection, and characterization of human parvovirus B19 infections among sickle cell anaemia patients in Khartoum State, Sudan
Published 2025-04-01“…However, the molecular mechanisms of infection remain poorly understood. Aim: This study aimed to determine the prevalence of human parvovirus B19 among patients with sickle cell anaemia in Khartoum State, Sudan. …”
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31819
Preliminary study assessing the long-term surgical outcomes of TBX6-associated congenital scoliosis (TACS) patients using the propensity score matching method: exploring the clinic...
Published 2025-01-01“…The specific genetic mechanism is not yet clear and may be related to the relatively normal development of paravertebral tissues in TACS patients. …”
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31820
N6-methyladenosine RNA modification regulates the transcription of SLC7A11 through KDM6B and GATA3 to modulate ferroptosis
Published 2025-01-01“…Abstract Background Recent studies indicate that N6-methyladenosine (m6A) RNA modification may regulate ferroptosis in cancer cells, while its molecular mechanisms require further investigation. Methods Liquid Chromatography-Tandem Mass Spectrometry (HPLC/MS/MS) was used to detect changes in m6A levels in cells. …”
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