Barriers and Facilitators to the Preadoption of a Computer-Aided Diagnosis Tool for Cervical Cancer: Qualitative Study on Health Care Providers’ Perspectives in Western Cameroon by Magali Jonnalagedda-Cattin, Alida Manoëla Moukam Datchoua, Virginie Flore Yakam, Bruno Kenfack, Patrick Petignat, Jean-Philippe Thiran, Klaus Schönenberger, Nicole C Schmidt

“…The HCPs emphasized the importance of clinical validation, usability testing, and iterative feedback mechanisms to build trust in the CAD tool’s accuracy and utility. …”
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Wearable Loop Sensors for Knee Flexion Monitoring: Dynamic Measurements on Human Subjects by Ian Anderson, Christopher Cosma, Yingzhe Zhang, Vigyanshu Mishra, Asimina Kiourti

“…The untethered sensor is validated upon a cylindrical phantom that is bent manually at random speed. A calibration mechanism is developed to derive the sensor-measured angles. …”
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Activity of trypsin inhibitors in common bean seeds (Phaseolus vulgaris L.) from the VIR collection: variability and source material for breeding by T. V. Buravtseva, G. P. Egorova, M. O. Burlyaeva, M. A. Nikishkina

“…The search for samples with high content of inhibitors is also relevant, since inhibitors play a crucial role in the functioning of the basic biochemical mechanisms that determine and regulate the physiological state of the cell.Materials and methods. …”
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GPR137-RAB8A activation promotes ovarian cancer development via the Hedgehog pathway by Chao Tang, Lin Li, Chongying Zhu, Qiang Xu, Zihao An, Shouying Xu, Chao Lin

“…Thus, further investigation of the mechanisms regarding OC carcinogenesis and discovery of novel targets is of great importance. …”
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Femoral neck system (FNS) versus 4 cannulated compression screws (CCSs) in the treatment of young patients with Pauwels type III femoral neck fracture: a retrospective comparative... by Yang Gao, Tianle Ma, Xiaohu Chang, Peng Jia, Xiaoteng Li, Xin Tang

“…Various demographic and clinical variables, including age, gender, fracture side, mechanism of injury, Garden classification, and time interval between injury and surgery, were collected. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Next, RNA-seq, COIP, Dual-luciferase reporter experiment, and CHIP-seq were used to explore the potential underlying mechanism. Results In our study, we investigated the role of HVEM in the microenvironment of NSCLC and its implications in immunotherapy. …”
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Effective control of southern blight and root rot of Aconitum carmichaelii Debeaux by endophytic Bacillus velezensis YN-2-6S by Qian Wang, Yujie Qiu, Siyu Wang, Yumei Gou, Hongji Hou, Tianwei Su, Lan Zou, Jing Huang

“…Taken together, this study proved that YN-2-6S was a promising biocontrol agent against southern blight and root rot of A. carmichaelii and the underline mechanism may involve the production of antifungal lipopeptides, polyketides, volatile compounds, hydrolysis and induction of host systemic resistance.…”
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Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…This study aimed to investigate the potential biological mechanisms underlying POCD. Methods Male C57BL/6 mice (2 and 17 months old) were randomly assigned to surgery or control groups. …”
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Spatiotemporal evolution and driving force analysis of drought characteristics in the Yellow River Basin by Meiying Wang, Yangbo Chen, Jingyu Li, Yanjun Zhao

“…Understanding the time-domain abrupt changes and evolutionary mechanisms of drought events is crucial for comprehending the water resource dynamics in the basin. …”
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Disparities in anxiety and related factors among Chinese older adults across different aged-care models: a comparison of two cross-sectional studies by Xin Zheng, Ziwen Xu, Jiajie Zhao, Sanyuan Hao, Fuqin Xu, Shuo Ding, Guoqing Liu, Shufan Yang, Benjamin Otsen, Wen Zhu, Zhongliang Bai, Jie Yang, Ren Chen

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MARVEL Analysis of the Measured High-resolution Spectra of 12C16O by Salman Mahmoud, Nayla El-Kork, Nariman Abu Elkher, Mubarak Almehairbi, Malathe Samir Khalil, Tibor Furtenbacher, Attila G. Császár, Olga P. Yurchenko, Sergey N. Yurchenko, Jonathan Tennyson

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Exploring the anticancer potential of extracts and compounds from the heartwood of Cotinus coggygria Scop. wild growing in Serbia by Ivana Pašić, Miroslav Novaković, Vele Tešević, Slobodan Milosavljević, Nina Petrović, Tatjana Stanojković, Ivana Z. Matić

“…The aim of study was to explore the cytotoxicity of extracts (EE-ethanol, MME-methylene chloride/methanol, and WE-water) and compounds (butin, butein, fisetin, sulfuretin, taxifolin, eriodictyol, fustin, cotinignan A, sulfuretin auronol, 3-O-methylepifustin, 3-O-methylfustin, and sitosterol-3-O-β-D-glucoside) isolated from C. coggygria. Mechanisms of anticancer effects of three extracts, butin, butein, and sulfuretin were examined. …”
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An efficient strategy to boost photoelectrochemical water oxidation of g-C3N4 films modified with NiO as cocatalyst by Lingling Bi, Jiahao Zhan, Wenhao Zhang, Zhenzhou Wu, Weichuan Xu, Xiaobo Liang, Lijing Zhang, Bin Yan, Chunyi Xu

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Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime by Frank W. Davis, Anne-Marie Parkinson, Max A. Moritz, Max A. Moritz, Isaac W. Park, Carla M. D’Antonio

“…The climate and fire vulnerability of BDF could be reduced by management actions such as mechanical fuel treatments and post-fire restoration, but these are highly constrained by topography, access, and sensitive wildlife species. …”
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miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis by ZhiYu Zhao, BoXia Li, DianWei Cheng, YuFang Leng

“…Conclusion In summary, miRNA-541-5p may be a biomarker of myocardial I/R damage diseases and can regulate oxidative stress and iron death by inhibiting the expression of miRNA-541-5p, thereby reducing mechanisms of I/R injury.…”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…As tubulin plays an important role in the mechanism of anthelmintics, the major compound of the most active extract (NR-EtOAc) rosmarinic acid was docked onto the colchicine-binding site of the tubulin (5OV7) protein. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…The therapeutic effects of migrasomes on airway inflammation in ovalbumin (OVA)-induced asthmatic mice were evaluated by hematoxylin-eosin (HE) and periodic-acid schiff (PAS) staining, and their mechanism were further testified by immunofluorescent staining, real-time PCR and flow cytometry. …”
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New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach by Yin Guan, Xiaoqian Zhao, Yun Lu, Yue Zhang, Yan Lu, Yue Wang

“…These findings support NBTL’s use as a promising candidate for RA treatment, emphasizing the need for further research on its mechanisms and clinical application.…”
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Exploring how graft length shapes root system architecture and morphology in grapevine rootstocks by Mathieu Larrey, Jean-Pascal Tandonnet, Clément Saint Cast, Sarah Jane Cookson, Philippe Vivin

“…The insights gathered here contribute to a deeper understanding of the mechanisms governing root development in grafted grapevines, thereby informing strategies to enhance grafting techniques and optimize grapevine cultivation. …”
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Simultaneous Debridement and Titanium Mesh Reconstruction in Patients with Compound Depressed Skull Fracture: A Retrospective Descriptive Study by Srikant Das, Acharya Suryakant Pattajoshi, Mahesh Kumar Kusta, Dibakar Sarkar

“…Results: The mean age of the subjects was 28.48±13.79 years. The predominant mechanism of injury was Road Traffic Accident (RTA), affecting 59 (60.2%) patients. …”
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