Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial by Marwa Khalil, Omar Hamadah, Maher Saifo

“…This trial aims to study the effect of preconditioning with photobiomodulation in preventing oral mucositis and xerostomia in cancer patients undergoing chemotherapy alone for the first time, and to examine its role in improving patients’ quality of life. Materials and methods This is a prospective, randomized, double-blind clinical trial including 45 patients divided into three age- and sex-matched groups. …”
Get full text

Observational research in epidemic settings: a roadmap to reform by Marc Lipsitch, Nicholas Evans, Alexandra L Phelan, Stephany N Duda, Annette Rid, Colin J Carlson, Jennifer B Rosen, Natalie E Dean, John Barugahare, Maya B Mathur, Emily E Ricotta, Fausto A Bustos Carrillo, Samuel Angelli-Nichols, Adia Benton, Emma Chang-Rabley, Lisa Federer, Mary-Margaret A Fill, Elizabeth C LeRoy, Natalie M Linton, Lauren Sauer, Sheena G Sullivan, Mackenzie Zendt

“…Resolving these challenges requires careful attention to prioritising the most valuable research questions, ensuring robust study design, strong data management practices, expansive community engagement, and access and benefit sharing of results and research materials. This paper opens with a discussion of how well-designed observational studies contribute to biomedical evidence and provides examples from across the clinical literature of how these methods generate hypotheses for future research and uncover otherwise unattainable insights by providing examples from across the clinical literature. …”
Get full text

Forensic Assessment of Alcohol Intoxication in Cases of Fatal Road Traffic Accidents in Lithuania by Beata Kirstukaitė, Akvilė Paškauskienė, Sigitas Chmieliauskas, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė

“…This study aims to examine the prevalence of alcohol in blood samples collected from the autopsy results of road traffic accident victims. Materials and methods: A retrospective study of 136 road traffic accident victims was performed in State Forensic Medicine Service of Lithuania in the period of 2013 to 2023. …”
Get full text

Utility of Visceral Adiposity Index and Lipid Accumulation Products to Define Metabolically-Unhealthy Polycystic Ovary Syndrome in Asian Indian Women - A Cross Sectional Study by R. A. Shreenidhi, Reeta Mahey, Monika Rajput, Rohitha Cheluvaraju, Ashish D. Upadhyay, Jai Bhagwan Sharma, Garima Kachhawa, Neerja Bhatla

“…Settings and Design: The design of the study was a cross-sectional study. Materials and Methods: Two hundred PCOS women were included in the study, and all the clinical, anthropometric, hormonal, biochemical and metabolic markers were assessed. …”
Get full text

From the Banks of the Orkhon to the Banks of the Neva: the History of Mining and Transit of Mongolian Gold to the Russian Empire at the beginning of the 20th century. by Aldar A. Shirapov, Anna M. Plekhanova

“…The purpose of the research is to study the mechanism of delivery of Mongolian gold to the Russian territory; identify and evaluate the role of the Russo-Chinese Bank and the Kyakhtinsky District Treasury in this process. Materials and methods. The study is based on the analysis of data from regulatory documents contained in the Complete Collection of Laws of the Russian Empire and previously unpublished cases from the funds of the State Archive of the Republic of Buryatia and the Russian State Historical Archive. …”
Get full text

Long-Term Monitoring of Liver Fibrosis and Steatosis in Patients with Chronic Hepatitis C after Achieving a Sustained Virologic Response to Antiviral Therapy by K. R. Dudina, P. A. Belyy, I. V. Maev, N. Kh. Safiullina, E. A. Klimova, S. A. Shutko, O. O. Znoyko, N.  D. Yushchuk

“…Aim: to analyze the dynamics of fibrosis and steatosis of the liver according to fibroelastometry in patients with chronic hep-atitis C (CHC) after ≥ 6 months from transient elastometry (TE) achieving a sustained virologic response (SVR) to antiviral therapy.Materials and methods. At baseline, a prospective observational study included 628 CHC patients with known stage of liver fibrosis (F) before AVT, some of whom were phased out due to non-compliance with the inclusion criteria. …”
Get full text

Detecting Atrial Fibrillation Using Smartwatches by Agnieszka Kulczycka-Rowicka, Julianna Podolec, Silvia Ciraolo, Joanna Wojda, Adam Sobiński, Zuzanna Kościuszko, Katarzyna Kurza, Matylda Czerwonka, Katarzyna Lesiczka-Fedoryj, Anna Walczak

“…The aim of this review is to analyze the latest information on the use of smartwatches in detecting atrial fibrillation.   Research materials and methods: This review draws on data sourced from the current literature and clinical reports from various sources. …”
Get full text

Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) by V. Т. Ivashkin, A. I. Ulyanin, I. V. Mayev, R. S. Kozlov, M. A. Livzan, S. R. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, D. S. Bordin, N. N. Dekhnich, N. V. Korochyanskaya, T. L. Lapina, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

“…Aim: to analyze current approaches to H. pylori eradication therapy in adults and present the materials of Experts Council held on December 9, 2022 in Moscow.General statements. …”
Get full text

Effectiveness of purple leaves (Graptophyllum pictum L. Griff) and hydroxyapatite as socket preservation biomaterials by Ratri Maya Sitalaksmi, Rizkipriyanto Azharpratomo, Shafira Ninditya Irsan, Primanda Nur Rahmania, Sisca Meida Wati, Syafira Salsabila Adam, Kavanila Bilbalqish, Khairul Anuar bin Shariff, Harry Laksono, Agus Dahlan, Devi Rianti

Get full text

Risk factors of 180-day rebleeding after management of blunt splenic injury without surgery and embolization: a national database study by Chung-Yen Chen, Hung-Yu Lin, Pie-Wen Hsieh, Yi-Kai Huang, Po-Chin Yu, Jian-Han Chen

“…Abstract Purpose This study aimed to identify risk factors for rebleeding within 180 days post-discharge in blunt splenic injury patients managed without splenectomy or embolization. Materials and methods A retrospective analysis was conducted using Taiwan’s National Health Insurance Research Database. …”
Get full text

Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…Estimation of an optimal corticosteroid (CS, prednisone) dosage for the remission induction in patients with ulcerative colitis (UC) and Crohn’s disease (CD) based on the construction of a dose-effect relationship during the first and second courses of therapy.Materials and methods. The study included 86 patients with moderate to severe active disease (61 with UC and 25 with CD) aged 18 to 65 years. …”
Get full text

Characterization of polyethylene and polyurethane microplastics and their adsorption behavior on Cu2+ and Fe3+ in environmental matrices by Ilaria Zanoni, Lucia Briccolani, Lara Faccani, Magda Blosi, Simona Ortelli, Matteo Crosera, Giovanna Marussi, Stefania Albonetti, Anna Luisa Costa

“…The zeta-potential measurements as a function of pH provided insights into the dispersion behavior of microplastics (MPs) in freshwaters, suitable for the growth of Zebrafish (Egg water) and Daphnia magna (Elendt M7 Water). Both materials showed in bidistilled water negative zeta potential (ZP) at natural pH (ZP = − 51.0 ± 4.3 mV at pH = 6.6 and ZP = − 29.5 ± 1.4 mV at pH = 5.6 for LDPE and PU, respectively), justified by the presence of surface-active charged impurities. …”
Get full text

Functional Evaluation of Open Carpal Tunnel Release in Carpal Tunnel Syndrome Patients by Swagat Mahapatra, Devta Singh, Prakhar Mishra, Jaydeep Patel, Madhusudan Mishra, Animesh Gupta

“…Objective: The objective of this study was to evaluate the functional outcome of open carpal tunnel release in carpal tunnel syndrome and analyze the risk factors and epidemiological patterns associated with carpal tunnel syndrome. Materials and Methods: This prospective cohort study was performed in the department of orthopedics at our institute for 8 months (January 2021 to August 2022) on carpal tunnel syndrome patients of either sex age ranging 20–60 years who attended orthopedic outpatient department and orthopedic wards, and who confirmed consent and found fitted according to inclusion criteria were recruited for this study. …”
Get full text

Internal Dosimetry in Patients Undergoing Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-[DOTA0-Tyr3] Octerotate: A Single-Center Experience by Elahe Mahmoudi, Mahasti Amoui, Mohammad Reza Deevband, Elahe Pirayesh, Mohammad Reza Asgari, Mehdi Ghorbani

“…This research aims to specify the absorbed dose to patients for the treatment of neuroendocrine tumors using imaging with 177Lu-[DOTA0-Tyr3] octerotate. Materials and Methods: Whole body planar scintigraphy images were collected for 10 patients, which are used as the basis for the personalized patient dosimetry calculations. …”
Get full text

A review of metabolic calorimetric applications in plant stress, waste management, and diagnostics by Michael Bayode, Ifeoluwaposi Ogundana, Oluwatosin Ogundare, Elizabeth Awodire, Patience Abbah, Israel Onifade, Adeola Adeyolanu, Stephen Okunade, Samuel Ogboye, Michael Elabiyi

“…Calorimetric studies of waste materials, wastewater sludge, and effluents were also considered in concert with specified thermophysical variables that define these environmental phenomena, such as enhanced thermal and heat capacity. …”
Get full text

Cognitive behavior therapy for academic burnout, procrastination, self-handicapping behavior, and test anxiety among adolescents: a randomized control trial by Khizra Khurshid, Rabia Mushtaq, Umara Rauf, Nida Anwar, Qasir Abbas, Sumayah Aljhani, Zoobia Ramzan, Mafia Shahzadi

“…The present study is designed to investigate the impact of cognitive behavioural therapy (CBT) on procrastination, burnout, self-handicapping behaviour, test anxiety, and school functioning among adolescents facing academic problems. Materials and methods A total of 200 adolescents were enrolled for eligibility assessment; 129 participants met the eligibility criteria, and they were allocated to the experimental and waitlist control conditions. …”
Get full text

Prediction of Reproductive Outcomes of Intracytoplasmic Sperm Injection Cycles Using a Multivariate Scoring System by Ahmed Abuelsoud Abden, Momen Ahmed Kamel, Ahmed Nabil Fetih, Ali Haroun Yousef

“…Settings and Design: This prospective observational cohort study (NCT03846388) included patients who pursued IVF or ICSI in a tertiary infertility unit between February 2019 and December 2021. Materials and Methods: The score variables were age, body mass index, antral follicle count, basal follicle-stimulating hormone (FSH), basal FSH/luteinising hormone ratio, infertility duration, number of previous cancellations and mean ovarian volume. …”
Get full text

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…However, there have been no reports on its efficacy in treating limb ischemia through promoting angiogenesis.Materials and Methods: In this study, we prepared AST-loaded lignin nanoparticles (LNP/AST) with sustained-release functionality, which were mixed with GelMA hydrogel (GelMA@LNP/AST). …”
Get full text

Features of the Parameters of 24-Hours pH-Impedance and High-Resolution Esophageal Manometry in Patients with Barrett's Esophagus on Proton Pump Inhibitors by I. V. Maev, D. S. Bordin, E. V. Barkalova, M. A. Ovsepyan, E. R. Valitova, N. G. Kalashnikova, D. N. Andreev

“…Аim: to identify predictors of insufficient effectiveness of proton pump inhibitors based on the evaluation of the results of 24-hour pH-impedance and high-resolution esophageal manometry in patients with Barrett's esophagus.Materials and methods. 52 patients with histologically confirmed Barrett's esophagus who are on therapy with proton pump inhibitors were examined. …”
Get full text

Evaluation of the relatedness between the biofilm-associated genes and antimicrobial resistance among Acinetobacter baumannii isolates in the southwest Iran by Nafiseh Hosseinzadeh Shakib, Zahra Hashemizadeh, Abolfazl Rafati Zomorodi, Reza Khashei, Yeganeh Sadeghi, Abdollah Bazargani

“…This study aims to explore the relationship between biofilm production, the presence of biofilm-associated genes, and antibiotic resistance patterns in A. baumannii isolates obtained from ICU patients. Materials and Methods: We collected 100 A. baumannii isolates from ICU patients at Nemazee Hospital in Shiraz, Iran. …”
Get full text