Isotropy of an Upper Limb Exoskeleton and the Kinematics and Dynamics of the Human Arm by Joel C. Perry, Janet M. Powell, Jacob Rosen

“…The aims of the research reported in this manuscript are (1) to study the kinematics and the dynamics of the human arm during daily activities in a free and unconstrained environment, (2) to study the manipulability (isotropy) of a 7-degree-of-freedom (DOF)-powered exoskeleton arm given the kinematics and the dynamics of the human arm in ADLs. …”
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Adeno-associated virus-based gene therapy for hemophilia–addressing the gaps by Wolfgang Miesbach, Paul Batty, Pratima Chowdary, Sylvia Fong, Radoslaw Kaczmarek, Frank W.G. Leebeek, Brian Long, Johnny Mahlangu, Mike Makris, Glenn F. Pierce, Steven W. Pipe, Alok Srivastava, Jan Voorberg, Flora Peyvandi

“…However, the complexity of gene therapy and the lack of standardization of methods in different components of this therapy can lead to unique challenges for clinical implementation. This manuscript follows literature reviews and structured discussions by the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee Working Group on Gene Therapy that identified specific areas requiring standardization of methods, including viral vector production, liver function assessment, quantification of factor (F)VIII and FIX expression levels, assessment of antiadeno-associated viral antibodies, and genomic integration detection methods. …”
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Privacy-preserving approach for IoT networks using statistical learning with optimization algorithm on high-dimensional big data environment by Fatma S. Alrayes, Mohammed Maray, Asma Alshuhail, Khaled Mohamad Almustafa, Abdulbasit A. Darem, Ali M. Al-Sharafi, Shoayee Dlaim Alotaibi

“…The data dimensional can have vague meaningful patterns, making it challenging to certify that privacy-preserving models do not destroy the efficacy and accuracy of statistical methods. This manuscript presents a Privacy-Preserving Statistical Learning with an Optimization Algorithm for a High-Dimensional Big Data Environment (PPSLOA-HDBDE) approach. …”
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Contextual adaptation of digital wellbeing interventions for young people: insights from a project in Saudi Arabia by Dahlia Aljuboori, Laura K. Clary, Saud Abdulaziz Alomairah, Saud Abdulaziz Alomairah, Michelle Colder Carras, Nazmus Saquib, Juliann Saquib, Fahad Albeyahi, Antonius J. Van Rooij, Anouk Tuijnman, Vincent G. Van der Rijst, Michelle R. Kaufman, Michelle R. Kaufman, Johannes Thrul, Johannes Thrul, Johannes Thrul

“…Our research team is conducting a series of studies - literature reviews, stakeholder engagement work, and a nationwide survey of adolescent digital media use - to inform, develop, and ultimately test school-based digital wellbeing intervention for high school students in Saudi Arabia. The goal of this manuscript is to explain our process of informing and creating an intervention that builds on previously established, evidence-based approaches, and is also tailored to a particular context (e.g., Saudi Arabia). …”
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Application of lipidomics in the study of traditional Chinese medicine by Yang Yang, Guangyi Yang, Wenpeng Zhang, Lingyi Xin, Jing Zhu, Hangtian Wang, Baodong Feng, Renyan Liu, Shuya Zhang, Yuanwu Cui, Qinhua Chen, Dean Guo

“…This analysis aids in uncovering potential mechanisms for treating diverse physiopathological conditions, assessing drug efficacy, understanding mechanisms of action and toxicity, and generating innovative ideas for disease prevention and treatment. This manuscript assesses recent literature, summarizing existing lipidomics technologies and their applications in TCM research. …”
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Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

“…The research scope covers a wide range of content from basic theory to practical cases, which has a guiding effect on clinical research.This manuscript is closely related to the core purpose and readership of Journal of Inflammation Research, a journal known for its in-depth and comprehensive coverage of the immune system and encouragement of original research. …”
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Study on the Key Influential Factors on Water Huff-n-Puff in Ultralow-Permeability Reservoir by Xiaoyan Wang, Kun Xie, Jie Zhang, Yong Zhang, Yang Zhang, Wei Wang, Xi Yan, Fengxiang Zhao

“…A systematic study on the related key influential factors of water huff-n-puff is done for improving the development effect of ultralow-permeability reservoirs. This manuscript studied the key influential factors of water huff-n-puff and related improving recovery methods using physical simulation experiments to put forward a beneficial condition for water huff-n-puff, combining with the field practice. …”
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Observations on old Serbian terminology for iron mining and processing: Želězo and gvozdje by Loma Aleksandar B.

“…Its only mention in a text written in Old Serbian spoken language is found in Dušan’s Code; the article in question deals with the ordeal of red-hot iron and has a close phraseological match in the Russian Justice manuscript, which suggests that its wording goes back to an oral formula of Slavic customary law. …”
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Gut Microbiota at the Crossroad of Hepatic Oxidative Stress and MASLD by Fabrizio Termite, Sebastiano Archilei, Francesca D’Ambrosio, Lucrezia Petrucci, Nicholas Viceconti, Roberta Iaccarino, Antonio Liguori, Antonio Gasbarrini, Luca Miele

“…Moreover, various exogenous factors impact gut microbiota and its involvement in MASLD-related oxidative stress, such as air pollution, physical activity, cigarette smoke, alcohol, and dietary patterns. This manuscript aims to provide a state-of-the-art overview focused on the intricate interplay between gut microbiota, lipid peroxidation, and MASLD pathogenesis, offering insights into potential strategies to prevent disease progression and its associated complications.…”
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QCD predictions for simultaneously produced Higgs and vector bosons at $$\sqrt{s}$$ s = 13, 14, 27 and 100 TeV with a comprehensive study of systematic uncertainty and charge asymm... by Kamuran Dilsiz, Emrah Tiras, Meryem Yilmaz, Hasan Ogul

“…Abstract A comprehensive study of high-order QCD cross-section for the Higgs boson that is simultaneously produced with a vector boson is presented at $$\sqrt{s} = 13, 14, 27$$ s = 13 , 14 , 27 and 100 TeV in this manuscript. The simultaneous Higgs production with a vector boson facilitates the investigation of the Higgs signal. …”
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Meals, Education, and Gardens for In-School Adolescents (MEGA): study protocol for a cluster randomised trial of an integrated adolescent nutrition intervention in Dodoma, Tanzania by Wafaie W Fawzi, Dongqing Wang, Abbas Ismail, Leonard Kamanga Katalambula, Andrea R Modest, Tara Young, Mary Mwanyika-Sando, Amani Tinkasimile, Dominic Mosha, Augustine Malero, Said Vuai

“…Chan School of Public Health (approval number: IRB20-1623), the Institutional Research Review Committee at the University of Dodoma (approval number: MA.84/261/02) and the Tanzania National Institute for Medical Research (approval number: NIMR/HO/R.8a/Vol. IX/3801). A manuscript with the research findings will be developed for publication. …”
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BSG 2024 IBD guidelines protocol (standard operating procedures) by Philip Smith, Rachel Cooney, Jimmy Limdi, Sreedhar Subramanian, Polychronis Pavlidis, Ajay Verma, Said Din, Gordon W Moran, Naila Arebi, Shahida Din, Morris Gordon, Kamal V Patel, Klaartje Bel Kok, Dennis McGonagle, Matthew Shale, Ana-Maria Darie, Vasiliki Sinopoulou, Newton A C S Wong

“…We present the prospective operating procedure and technical summary protocol in the manuscript.Methods ‘Grading of Recommendations Assessment, Development and Evaluation’ (GRADE) will be followed in the development of the guideline, approach as laid out in the GRADE handbook, supported by the WHO. …”
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Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption by Yi Zhang, Yongding He, Meixin Yan, Shilong Zhang, Sisi Zhou, Wankuan Shen

“…Therefore, it is very necessary to study the pathogenic mechanism of S. scitamineum, especially at the molecular level. This manuscript identified a new pathogenic gene and discovered a new pathogenic mechanism of this gene in S. scitamineum, enriched the molecular pathogenesis of S. scitamineum, and provided a new target for the prevention and control of sugarcane smut disease.…”
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Fatigue in patients with chronic obstructive pulmonary disease: protocol of the Dutch multicentre, longitudinal, observational FAntasTIGUE study by Mirjam A G Sprangers, Martijn A Spruit, Emiel F M Wouters, Daisy J A Janssen, Jean W M Muris, Judith B Prins, Yvonne M J Goërtz, Milou Looijmans, Melissa S Y Thong, Jeannette B Peters, Chris Burtin, Yvonne Meertens-Kerris, Arnold Coors, Jan H Vercoulen

“…The secondary aim is to identify diurnal differences in fatigue by using ecological momentary assessment (EMA). This manuscript describes the protocol of the FAntasTIGUE study and gives an overview of the possible strengths, weaknesses and clinical implications.Methods and analysis A 2-year longitudinal, observational study, enrolling 400 patients with clinically stable COPD has been designed. …”
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Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation by Eliot G. Peyster, MD, MSc, Cai Yuan, PhD, Sara Arabyarmohammadi, PhD, Priti Lal, MD, Michael D. Feldman, MD, PhD, Pingfu Fu, PhD, Kenneth B. Margulies, MD, MS, Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI

“…Data Availability: The data that support the findings of this study are presented in the manuscript and extended data sections. Unprocessed raw data are available from the corresponding author upon reasonable request. …”
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Refining Established Practices for Research Question Definition to Foster Interdisciplinary Research Skills in a Digital Age: Consensus Study With Nominal Group Technique by Jana Sedlakova, Mina Stanikić, Felix Gille, Jürgen Bernard, Andrea B Horn, Markus Wolf, Christina Haag, Joel Floris, Gabriela Morgenshtern, Gerold Schneider, Aleksandra Zumbrunn Wojczyńska, Corine Mouton Dorey, Dominik Alois Ettlin, Daniel Gero, Thomas Friemel, Ziyuan Lu, Kimon Papadopoulos, Sonja Schläpfer, Ning Wang, Viktor von Wyl

“…For the workshops and the subsequent manuscript writing process, we adopted a consensus study methodology. …”
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Introducing ‘trident’: a graphical interface for discriminating groups using dental microwear texture analysis by Thiery, Ghislain, Francisco, Arthur, Louail, Margot, Berlioz, Emilie, Blondel, Cécile, Brunetière, Noël, Ramdarshan, Anusha, Walker, Axelle EC, Merceron, Gildas

“…This manuscript introduces trident, an R package for performing dental microwear texture analysis and subsequently classifying variables based on their ability to separate discrete categories. …”
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A dataset of Zostera marina and Zostera noltei structure and functioning in four sites along the French coast over a period of 18 months by Lacoste, Elise, Ouisse, Vincent, Desroy, Nicolas, Allano, Lionel, Auby, Isabelle, Bajjouk, Touria, Bourdier, Constance, Caisey, Xavier, De Casamajor, Marie-Noelle, Cimiterra, Nicolas, Cordier, Céline, Curd, Amélia, Derrien, Lauriane, Droual, Gabin, Dubois, Stanislas, Foucault, Elodie, Foveau, Aurélie, Gaffet, Jean-Dominique, Ganthy, Florian, Gionaroli, Camille, Ignacio-Cifre, Rachel, Liabot, Pierre-Olivier, Messiaen, Gregory, Meteigner, Claire, Monnier, Benjamin, Van Paemelen, Robin, Pasquier, Marine, Rigouin, Loic, Rollet, Claire, Royer, Aurélien, Soissons, Laura, Tancray, Aurélien, Blanchet-Aurigny, Aline

“…This manuscript describes the methodology associated with the dataset entitled: A dataset of Zostera marina and Zostera noltei structure and functioning in four sites along the French coast over a period of 18 months. …”
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Impact of Nutritional Support for Tuberculosis on Intermediate and Terminal Undernutrition and Treatment Outcomes (INSTITUT) study: a protocol for a quasi-experimental study to ass... by Dissou Affolabi, Chelsie Cintron, Madolyn Dauphinais, Attannon Arnauld Fiogbe, Mohammed Fall Dogo, Safiou Ate, Christine Adjonou, Kokou Agossou, Susie Jiaxing Pan, Marius Esse, Benjamin Ade, Komi Séraphin Adjoh, Pranay Sinha, Kobto G Koura

“…Findings from the study will be disseminated via national and international conferences and through manuscript publications in peer-reviewed journals. Data can be made available upon request to the corresponding author.Trial registration number NCT06084715. …”
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A qualitative process evaluation of SBIRT implementation in pediatric trauma centers using the Science to Service Laboratory implementation strategy by Kelli Scott, Michael J. Mello, Geraldine Almonte, Emely Arenas Lemus, Julie R. Bromberg, Janette Baird, Anthony Spirito, Mark R. Zonfrillo, Karla Lawson, Lois K. Lee, Emily Christison-Lagay, Stephanie Ruest, Jeremy Aidlen, Andrew Kiragu, Charles Pruitt, Isam Nasr, Robert Todd Maxson, Beth Ebel, Sara J. Becker

“…The Implementing Alcohol Misuse Screening, Brief Intervention, and Referral to Treatment Study (IAMSBIRT) aimed to implement SBIRT across 10 pediatric trauma centers using the Science-to-Service Laboratory (SSL), an empirically supported implementation strategy. This manuscript aimed to assess trauma center staff preferences and experience with the didactic training, performance feedback, and ongoing coaching elements of the SSL via a retrospective qualitative process evaluation. …”
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