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401
Identification of Olfactory Receptors Responding to Androstenone and the Key Structure Determinant in Domestic Pig
Published 2024-12-01“…Olfactory receptors (ORs) are members of the transmembrane G protein-coupled receptor superfamily, playing a crucial role in odor recognition, which further mediates crucial biological processes in mammals. In sows, androstenone can trigger sexual behaviors through olfaction, but the underlying mechanism remains to be explored. …”
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402
Generation of live mice from haploid ESCs with germline-DMR deletions or switch
Published 2025-01-01“…Abstract Genomic imprinting is required for sexual reproduction and embryonic development of mammals, in which, differentially methylated regions (DMRs) regulate the parent-specific monoallelic expression of imprinted genes. …”
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403
Structure-activity relationship and in silico docking analysis of dicarboximide fungicides on 17β-hydroxysteroid dehydrogenase 1 of human, rat, and pig
Published 2025-01-01“…Dicarboximide fungicides, including captafol, captan, cyclohexylthiophthalimide, folpet, and procymidone, represent a distinct category of fungicides. 17β-Hydroxysteroid dehydrogenase 1 (17β-HSD1) catalyzes the conversion of estrone to estradiol in mammals. Yet, the impact of these fungicides on 17β-HSD1 activity remains unknown. …”
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404
The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity
Published 2019-05-01“…Cerox1 function is conserved across placental mammals: human and mouse orthologues effectively modulate complex I enzymatic activity in mouse and human cells, respectively. …”
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405
Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway
Published 2025-02-01“…As an upstream component of the pathway and lacking a homolog in mammals, Sdd3 has the potential to serve as an antifungal target for biofilm infections.IMPORTANCEThe human fungal pathogen Candida albicans is categorized as a critical priority pathogen on the World Health Organization’s Fungal Priority Pathogens List. …”
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406
Phenotypic and Complete Reference Whole Genome Sequence Analyses of Two <i>Paenibacillus</i> spp. Isolates from a Gray Wolf (<i>Canis lupus</i>) Gastrointestinal Tract
Published 2025-01-01“…Inflammatory bowel disease (IBD) is increasing among mammals around the world, and domestic dogs are no exception. …”
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407
Characterization of the C5H11ORF96 gene in chickens: cloning, tissue distribution and investigation of its potential function in stress response regulation
Published 2025-01-01“…Our results showed that: (1) cC5H11ORF96 cDNA encodes a 120 amino acids protein, which shares high sequence identity with that of birds, mammals, reptiles, frogs and fish; (2) cC5H11ORF96 has a fully conserved RFKTQP motif and high proportion of serine, indicating its multiple potential phosphorylation sites; (3) cC5H11ORF96 is widely expressed in various chicken tissues, with high expression levels in the parathyroid gland, adrenal gland, and pituitary; (4) glucocorticoids (GCs) and stress significantly upregulate C5H11ORF96 mRNA and protein expression in the chicken pituitary and hypothalamus, suggesting its involvement in regulating stress response by influencing the negative feedback of GCs on the HPA axis in chickens. …”
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408
Copy Number Variations in Short Tandem Repeats Modulate Growth Traits in Penaeid Shrimp Through Neighboring Gene Regulation
Published 2025-01-01“…In this study, we systematically identified and compared STRs across multiple species, confirming a significantly higher prevalence of STRs (26–32%) in penaeid shrimp, which is markedly higher than that observed in other species, such as mammals (1.3–2.1%) and plants (0.21–0.73%). Further analysis utilizing a cohort of 326 Pacific white shrimp revealed a total of 672,507 high-quality STRs evenly distributed across the genome, with a notably lower frequency of SNPs within these STR regions. …”
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409
Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosisResearch in context
Published 2025-02-01“…Summary: Background: Leptospirosis is a globally neglected re-emerging zoonosis affecting all mammals, albeit with variable outcomes. Humans are susceptible to leptospirosis; infection with Leptospira interrogans species can cause severe disease in humans, with multi-organ failure, mainly affecting kidney, lung and liver function, leading to death in 10% of cases. …”
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410
Metabolic changes before and after weaning in Dezhou donkey foals in relation to gut microbiota
Published 2024-01-01“…Many studies have shown that the intestinal microbiota and serum metabolites of mammals exhibit different changes during lactation, weaning, and postweaning. …”
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411
Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey
Published 2024-05-01“…This study represents a first investigation of the long-term effects of carrion pulses, whose frequency may increase with climate changes, on the classical predator-prey coupling for large mammals.…”
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412
Exocyst complex component 1 (Exoc1) loss in dormant oocyte disrupts c-KIT and growth differentiation factor (GDF9) subcellular localization and causes female infertility in mice
Published 2025-01-01“…Abstract A limited number of female germ cells support reproduction in many mammals. The follicle, composed of oocytes and supporting granulosa cells, forms the basis of oogenesis. …”
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413
Enhancing reproductive capacity in hybrid Red Tilapia (Oreochromis niloticus × O. mossambicus) via dietary administration of date palm pollen (Phoenix dactylifera L.)
Published 2025-04-01“…While DPP may offer various health benefits, including potential positive effects on reproductive performance in mammals, its impact on reproductive health in fish remains largely unexplored. …”
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414
Revealing the biological features of the axolotl pancreas as a new research model
Published 2025-01-01“…Notably, the adult axolotl pancreas exhibits slower metabolic activity compared to mammals, as evidenced by the results of GTT and ITT. …”
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415
gga-miR-6634-5p Affects the proliferation and steroid hormone secretion of chicken (Gallus Gallus) granulosa cells by targeting MMP16
Published 2025-01-01“…However, research on the role of miRNAs in the ovulation process of chicken ovaries is still insufficient compared to that in mammals. Here, we investigated the regulatory mechanisms of gga-miR-6634-5p in the growth and steroid hormone secretion of chicken granulosa cells (GCs) by targeting MMP16. …”
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416
Stage-dependent changes in culture medium osmolality promote porcine oocyte maturation in vitro
Published 2025-01-01“…IntroductionEarly preimplantation embryos of mammals exhibit pronounced sensitivity to hyperosmotic conditions, which results in an embryonic developmental block. …”
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417
Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring
Published 2025-01-01“…Overall, maternal exposure to PS-NPs induced profound and enduring effects on the reproductive functions of female offspring, raising critical alarms regarding the multigenerational reproductive toxicity risks associated with nanoplastic exposure in mammals.…”
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418
First Detection of <i>Alphacoronavirus</i> in Bats from the World’s Largest Wetland, the Pantanal, Brazil
Published 2025-01-01“…They represent 40% of the total number of mammal species in the Pantanal, a biodiversity hotspot in South America. …”
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419
Liver morphometry and histopathology effects in Astyanax lacustris exposed to lambda-cyhalothrin pyrethroid insecticide
Published 2025-06-01“…Lambda-cyhalothrin (LC) is a pyrethroid insecticide employed to manage various arthropods as an alternative to persistent insecticides with minimized toxic effects on birds and mammals. However, LC causes oxidative and neurotoxic damages in fish Danio rerio. …”
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420
The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters
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