Suggested Topics within your search.
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- Embryology 1
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261
Helminth Parasites and the Modulation of Joint Inflammation
Published 2011-01-01“…Helminth parasites are accomplished masters at modifying their hosts' immune activity, and so attention has focused on rodent-helminth model systems to uncover the workings of the mammalian immune response to metazoan parasites, with the hope of revealing molecules and/or mechanisms that can be translated into better treatments for human autoimmune and idiopathic disorders. …”
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262
Disruption of erythroid nuclear opening and histone release in myelodysplastic syndromes
Published 2019-03-01“…Abstract Mammalian terminal erythropoiesis involves several characteristic phenomena including chromatin condensation and enucleation. …”
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263
Identification of a Gene Sharing a Promoter and Peroxisome Proliferator-Response Elements With Acyl-CoA Oxidase Gene
Published 2006-01-01“…Many mammalian genes are clustered on the genomes, and hence the genes in the same cluster can be regulated through a common regulatory element. …”
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264
Purification of Anti-Mycobacterium tuberculosis MPT64 Immunoglobulin-Y from Egg-Yolk Supernatant Using Thiophilic Adsorption Chromatography
Published 2024-03-01“… The significance of immunoglobulin Y (IgY) as a particular antibody equal to mammalian IgG is well understood. However, due to a lack of reliable purification procedures, producing highly pure IgY remains problematic. …”
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265
Desmosomal Molecules In and Out of Adhering Junctions: Normal and Diseased States of Epidermal, Cardiac and Mesenchymally Derived Cells
Published 2010-01-01“…Of these special cell-cell junctions containing desmosomal glycoproteins or proteins we review the composite junctions (areae compositae) connecting the cardiomyocytes of mature mammalian hearts and their importance in relation to human arrhythmogenic cardiomyopathies. …”
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266
Plant thionins: structure, biological functions and potential use in biotechnology
Published 2018-09-01“…Thionins are toxic to different types of cells including mammalian cancer cell lines. Transgenic plants expressing thionin genes display enhanced resistance to pathogens. …”
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267
Silvicultural Attempts to Induce Browse Resistance in Conifer Seedlings
Published 2011-01-01“…It appears that silvicultural manipulation via sulfur application and/or soil amendment cannot accelerate or alter the ontogenetical changes that may naturally defend seedlings against mammalian herbivores. In a brief trial with captive deer, redcedar browse resistance was influenced by seedling maturation, but not monoterpene content. …”
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268
Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration
Published 2017-01-01“…Sirtuins are highly conserved lysine deacetylases involved in ageing, energy production, and lifespan extension. The mammalian SIRT2 has been implicated in Parkinson’s disease (PD) where studies suggest SIRT2 promotes neurodegeneration. …”
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269
Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase
Published 2019-01-01“…Influenza A viruses (IAV) are evolutionarily successful pathogens, capable of infecting a number of avian and mammalian species and responsible for pandemic and seasonal epidemic disease in humans. …”
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270
<i>Trypanosoma cruzi</i>: Genomic Diversity and Structure
Published 2025-01-01“…Trans-sialidases are the most prevalent genes in the genome with a key role in the infection process, while mucins and MASPs are also significant glycosylated proteins expressed on the parasite surface, essential for its biological functions, as host–parasite interaction, host cell invasion or protection against the host immune system, in both insect and mammalian stages. Collectively, in this review, some of the most recent advances in the structure and composition of the <i>T. cruzi</i> genome are reviewed.…”
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271
Genome editing using CRISPR/ Cas9 system: a practical guide
Published 2017-02-01“…Nowadays, CRISPR/Cas systems can be used not only to modify genomes, but also to control expression levels of defined genes, visualize loci of interest in the space of living cell nuclei, change methylation status of mammalian CpG sites, and to serve many other purposes. …”
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272
Hyaluronan Synthesis, Catabolism, and Signaling in Neurodegenerative Diseases
Published 2015-01-01“…The glycosaminoglycan hyaluronan (HA), a component of the extracellular matrix, has been implicated in regulating neural differentiation, survival, proliferation, migration, and cell signaling in the mammalian central nervous system (CNS). HA is found throughout the CNS as a constituent of proteoglycans, especially within perineuronal nets that have been implicated in regulating neuronal activity. …”
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273
Clinicopathological features of two ultra-rare cases of malignant perivascular epithelioid cell tumors (PEComas) involving the uterus with recent updates
Published 2023-01-01“…In view of multiple tumor deposits, the second patient was induced with a mammalian target of rapamycin (m-TOR) inhibitor (everolimus) but unfortunately died of the disease. …”
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274
CUL4-Based Ubiquitin Ligases in Chromatin Regulation: An Evolutionary Perspective
Published 2025-01-01“…Although Cullin (CUL) proteins lack intrinsic enzymatic activity, they participate in the formation of active ubiquitin ligase complexes, known as Cullin-Ring ubiquitin Ligases (CRLs), through their association with ROC1 or ROC2, along with substrate adaptor and receptor proteins. Mammalian genomes encode several CUL proteins (CUL1–9), each contributing to distinct CRLs. …”
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275
Cytomegalovirus Infection in Patient with Clear Cell Renal Cell Carcinoma
Published 2023-01-01“…In this case report, we present the case of a 61-year-old man with clear cell renal cell carcinoma who underwent targeted therapy with the receptor tyrosine kinase (RTK) inhibitor lenvatinib and the mammalian target of rapamycin (mTOR) inhibitor everolimus. …”
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276
A scoping review of evidence of naturally occurring Japanese encephalitis infection in vertebrate animals other than humans, ardeid birds and pigs.
Published 2024-10-01“…Indirect evidence (antibodies) was identified in several mammalian and avian orders, as well as reported in two reptile species. …”
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277
Genomic and Computational Analysis of Novel SNPs in TNP1 Gene Promoter Region of Bos indicus Breeding Bulls
Published 2022-01-01“…Transition nuclear proteins (TNPs), the principal proteins identified in the condensing spermatids chromatin, have been found to play a key role in histone displacement and chromatin condensation during mammalian spermatogenesis. One such gene belonging to the TNP family called TNP1 gene is abundantly expressed in the regulation of spermatogenesis, and its sequence is remarkably well conserved among mammals. …”
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278
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.
Published 2004-08-01“…We report that mon encodes the zebrafish ortholog of mammalian transcriptional intermediary factor 1gamma (TIF1gamma) (or TRIM33), a member of the TIF1 family of coactivators and corepressors. …”
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279
Reorganisation of chromatin during erythroid differentiation
Published 2019-02-01“…Throughout erythropoiesis cells undergo a dramatic reorganization of the chromatin landscape leading to global nuclear condensation and transcriptional silencing, followed by nuclear extrusion at the final stage of mammalian erythropoiesis. Drastic changes of genome architecture and function accompanying erythroid differentiation seem to be an informative model for studying the ways of how genome organization and dynamic gene activity are connected. …”
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280
LeaData a novel reference data of leather images for automatic species identification
Published 2025-02-01“…Abstract In the leather industry, the mammalian skins of buffalo, cow, goat, and sheep are the permissible materials for leather-making. …”
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