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1241
The effect of nuclear transcriptional factor κВ activation inhibitor – curcumine on the experimental immune liver disease
Published 2010-02-01“…At Т-cellular hepatitis cytolytic component of liver lesion, primary and secondary cell necrosis, depression of cytophagous activity of macrophages that causes preconditions for enhancement of inflammation were more intensive. …”
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1242
miR-155: An Important Role in Inflammation Response
Published 2022-01-01“…We analyze the articles about miR-155 for nearly five years, review the advanced study on the function of miR-155 in different inflammatory cells like T cells, B cells, DCs, and macrophages, and then summarize the biological functions of miR-155 in different inflammatory cells. …”
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1243
T Cell Activation and Regulation of HIV-1: Same Effectors with Distinct Outcomes
Published 1999-01-01“…For example, the viral promoter, as is the case for the immune system, is subject to complex regulation by combinations of cellular transcription factors that may quantitatively and/or qualitatively differ depending on cell types (eg, macrophages versus T lymphocytes) and cell states (eg, undifferentiated versus differentiated or quiescent versus activated). …”
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1244
A sequencing-based method for quantifying gene-deletion mutants of bacteria in the intracellular environment
Published 2025-01-01“…Further, the method was used to quantify mutants of S. Gallinarum in macrophages. Six mutants and one control strain were mixed in a pool and allowed to infect HD11 cells for 2 h. …”
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1245
Immunomodulatory effect of ethanol-soluble oligopeptides from Atlantic cod (Gadus morhua)
Published 2023-07-01“…It promoted the release of NO and the expression of iNOS, TNF-α, IL-6 and IL-1β genes in macrophages, suggesting that CP-ES may regulate innate immunity. …”
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1246
Isolation and Bioactivity Analysis of Ethyl Acetate Extract from Acer tegmentosum Using In Vitro Assay and On-Line Screening HPLC-ABTS+ System
Published 2014-01-01“…The anti-inflammatory activities and on-line screening HPLC-ABTS+ assay method of these compounds in LPS-stimulated murine macrophages were rapid and efficient for the investigation of bioactivity of A. tegmentosum.…”
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1247
Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39
Published 2025-01-01“…Abstract Microglia and the border-associated macrophages contribute to the modulation of cerebral blood flow, but the mechanisms have remained uncertain. …”
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1248
LANCL1 as the Key Immune Marker in Neuropathic Pain
Published 2022-01-01“…Cascade reactions including mast cells, macrophages, and T cells may be an important reason for the aggravation of nerve damage.…”
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1249
Therapeutic implications for the PD-1 axis in cerebrovascular injury
Published 2025-01-01“…In myeloid cells, PD-1 stimulation induces polarization of microglia and macrophages into an anti-inflammatory, restorative phenotype. …”
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1250
Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance
Published 2025-02-01“…The tumor microenvironment, particularly interactions with cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs), further complicates treatment by promoting aggressive tumor behavior and immune evasion. …”
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1251
Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications
Published 2021-01-01“…Histopathological correlates of HRF are not univocal, spacing from migrating retinal pigment epithelium cells, lipid-laden macrophages, microglial cells, and extravasated proteinaceous or lipid material. …”
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1252
Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
Published 2013-01-01“…Microscopic findings of the left kidney revealed infiltration of lymphocytes and lipid-laden macrophages (xanthoma cells) corresponding to XGP.…”
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1253
Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis
Published 2024-01-01“…This review comprehensively explores the biology of exosome-derived miRNAs, which originate from both immune cells (such as macrophages and dendritic cells) and nonimmune cells (such as endothelial and epithelial cells) and play a dynamic role in modulating pathways that affect the course of sepsis, including those related to inflammation, immune response, cell survival, and apoptosis. …”
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1254
Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis
Published 2020-01-01“…Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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1255
NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
Published 2025-01-01“…This research aimed to explore how NF-κB influences the recruitment and polarization of tumor-associated macrophages and myeloid-derived suppressor cells, both of which contribute to immunosuppression. …”
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1256
Metastatic Calcinosis of Aortic Valve Secondary to Renal Failure Mimicking Infective Endocarditis
Published 2016-01-01“…Later on, biopsy of her hand lesions showed extensive calcification with macrophages and giant cells. No atypia or malignancy was identified. …”
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1257
Inflammation in Diabetic Nephropathy
Published 2012-01-01“…We highlight the important role of inflammatory cells in the kidney, particularly infiltrating macrophages, T-lymphocytes and the subpopulation of regulatory T cells. …”
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1258
The Effects of Mesenchymal Stem Cells on Antimelanoma Immunity Depend on the Timing of Their Administration
Published 2020-01-01“…On the contrary, MSCs, injected 14 days after melanoma induction (B16F10+MSC14d-treated mice), promoted tumor growth by suppressing antigen-presenting properties of tumor-infiltrating dendritic cells (DCs) and macrophages and by reducing tumoricidal capacity of NK cells and T lymphocytes. …”
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1259
Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage
Published 2025-02-01“…The resulting CovSAla318Val mutation caused a significant upregulation of SLO resulting in increased inflammasome activation in human THP-1 macrophages, indicating an enhanced inflammatory potential. …”
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1260
Impact of Thrombopoietin Receptor Agonists on Pathophysiology of Pediatric Immune Thrombocytopenia
Published 2025-01-01“…Various pathophysiological mechanisms are implicated in ITP pathogenesis, including the production of autoantibodies against components of platelets (PLTs) by B-cells, the activation of the complement system, phagocytosis by macrophages mediated by Fcγ receptors, the dysregulation of T cells, and reduced bone marrow megakaryopoiesis. …”
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