Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization by Syed A. H. Zaidi, Ruth B. Caldwell, Modesto A. Rojas

“…We show that OIR-induced activation of macrophage/microglial cells, retinal inflammation, and pathological RNV are mediated by increases in cholesterol ester (CE) formation due to activation of the acyl-CoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) enzyme.…”
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Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor by Zikang Zhang, Kangdi Zheng, Zhao Zhang, Longbin Cao, Lizhu Lin, Weimin Sun, Feng Qiu

“…To better understand the interaction between female genital tract microbiome and immune function, the immunomodulatory activities of L. gasseri LGV03 were investigated in zebrafish models of neutropenia, macrophage and T cells deficiency. L. gasseri LGV03 showed higher potent activities in ameliorating vinorelbine-induced neutropenia, macrophage and T cells deficiency, and significantly enhanced mRNA expressions of cytokines TNF-α, TNF-β and IFN-α. …”
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Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis by Chiu-Li Yeh, Li-Han Su, Jin-Ming Wu, Po-Jen Yang, Po-Chu Lee, Po-Da Chen, Chun-Chieh Huang, Der-Yirng Hsieh, Hsueh-Ju Wang, Sung-Ling Yeh, Ming-Tsan Lin

“…Also, expressions of inflammatory cytokines and macrophage infiltration markers in adipose tissues and lungs were elevated. …”
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Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy by Tarek Kamal Abouzed, Seiichi Munesue, Ai Harashima, Yusuke Masuo, Yukio Kato, Khaled Khailo, Hiroshi Yamamoto, Yasuhiko Yamamoto

“…Salicylate showed beneficial effects on diabetic nephropathy similar to those of pyridoxamine, which include lowering blood glucose levels and inhibiting macrophage infiltration into the kidneys. Attenuation of macrophage infiltration into the kidneys and upregulation of antiglycating enzyme glyoxalase 1 gene expression were found only in the salicylate treatment group. …”
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Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain by Wen S. Sheng, Priyanka Chauhan, Shuxian Hu, Sujata Prasad, James R. Lokensgard

“…Multicolor flow cytometry was used to determine the effects of CB2R agonists on macrophage activation and T-lymphocyte infiltration into dorsal root ganglia (DRG) and lumbar spinal cord (LSC). …”
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Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…Abstract Abundant infiltration of tumor-associated macrophages (TAMs) within the tumor stroma plays a pivotal role in inducing immune escape in pancreatic cancer (PC). …”
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Cytokines and Water Distribution in Anorexia Nervosa by Hubertus Himmerich, Bethan Dalton, Olivia Patsalos, Ulrike Schmidt, Iain C. Campbell

“…Following blood collection, 27 cytokines and chemokines were quantified using multiplex ELISA-based technology: Eotaxin, Eotaxin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon- (IFN-) γ, interleukin- (IL-) 1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, interferon γ-induced protein- (IP-) 10, macrophage inflammatory protein- (MIP-) 1α, MIP-1β, monocyte chemoattractant protein- (MCP-) 1, MCP-4, thymus and activation-regulated chemokine (TARC), TNF-α, and TNF-β. …”
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Chemokine Profiles Are Affected in Serum of Patients with Acute Rejection of Kidney Allograft by Lenka Krupickova, Martina Fialova, Marek Novotny, Veronika Svachova, Kristyna Mezerova, Eva Cecrdlova, Ondrej Viklicky, Ilja Striz

“…On the other hand, adding of monocytes/macrophages to a culture of renal epithelial cells suppressed the release of CXCL10 and CXCL11 attracting T lymphocytes. …”
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ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice by Ninon Foussard, Célia Bourguignon, Virginie Grouthier, Caroline Caradu, Candice Chapouly, Alain-Pierre Gadeau, Thierry Couffinhal, Marie-Ange Renault

“…This was associated with an increased macrophage infiltration and an impaired myocyte differentiation. …”
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The Role of TAMs in Tumor Microenvironment and New Research Progress by Yawei Feng, Zhiqiang Ye, Furong Song, Yufeng He, Jun Liu

“…Tumor-associated macrophages (TAMs) are an important part of tumor microenvironment (TME) and play a key role in TME, participating in the process of tumor occurrence, growth, invasion, and metastasis. …”
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Pivotal Roles of GM-CSF in Autoimmunity and Inflammation by Aoi Shiomi, Takashi Usui

“…Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor, which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells. …”
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The Role of MIF in Type 1 and Type 2 Diabetes Mellitus by Yuriko I. Sánchez-Zamora, Miriam Rodriguez-Sosa

“…Both processes are orchestrated by inflammatory cytokines, including the macrophage migration inhibitory factor (MIF). To date, MIF has been implicated in both types of diabetes; therefore, understanding the role of MIF could affect our understanding of the autoimmune or inflammatory responses that influence diabetic pathology. …”
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Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida by Benjamin Billings, Neeka Akhavan, Amy Vittor, Ying Nagoshi

“…Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. …”
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Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation by Chang Xia, Xiaoquan Rao, Jixin Zhong

“…Inflammatory regulation has been focused on innate immunity especially macrophage for a long time, while increasing evidence suggests T cells are crucial for the development of metabolic inflammation and insulin resistance since 2009. …”
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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

“…Digital spatial profiling analysis of PDAC samples demonstrates the colocalization of TIMP-1high macrophages and CD63high cancer cells. The presence of TIMP-1high macrophages and CD63high epithelial cells correlates with poor prognosis in PDAC. …”
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IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

“…OI promoted the transformation of macrophages into M2 macrophages, and this was inhibited when TIM4 was blocked. …”
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IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M by Fernando Botelho, Anisha Dubey, Ehab A. Ayaub, Rex Park, Ashley Yip, Allison Humbles, Roland Kolbeck, Carl D. Richards

“…In vitro, IL-33 upregulated expression of OSM in the RAW264.7 macrophage cell line and in bone marrow-derived macrophages. …”
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Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

“…Analysis of scFv binding and blocking function was evaluated by flow cytometry in macrophage-like THP-1 cells and hepatocellular carcinoma HepG2 cells. …”
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Screening of Anti-Inflammatory Components of Qin Jin Hua Tan Tang by a Multivariate Statistical Analysis Approach for Spectrum-Effect Relationships by Feipeng Duan, Yisheng Li, Meizhen Zhao, Tianyong Hu, Xinquan Pan, Yue Feng, Fang Ma, Shuqi Qiu, Yiqing Zheng

“…These four bioactive components significantly inhibited the secretion of inflammatory factors in the lipopolysaccharide-stimulated macrophage cell line. This research successfully screened the QJHTT anti-inflammatory active ingredient group. …”
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MSC-Derived Exosome Promotes M2 Polarization and Enhances Cutaneous Wound Healing by Xiaoning He, Zhiwei Dong, Yina Cao, Han Wang, Shiyu Liu, Li Liao, Yan Jin, Lin Yuan, Bei Li

“…In this study, early depletion of macrophages delayed the wound repair with MSC injection, which suggested that MSC-mediated wound healing required macrophages. …”
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