-
81
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
Published 2025-04-01“…Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases of the disease and there is a substantial golden period between the formation of polyps and the onset of cancer. …”
Get full text
Article -
82
Genetic evidence for the causal effects of air pollution on the risk of respiratory diseases
Published 2025-01-01“…Results: TSMR analysis revealed that exposure to PM2.5 increased the risk of early-onset chronic obstructive pulmonary disease (COPD), pneumonia, pulmonary embolism and lung cancer. PM2.5–10 exposure was associated with an increased risk of lung cancer, while PM10 exposure increased the risk of pneumonia and bronchiectasis. …”
Get full text
Article -
83
Cross-ViT based benign and malignant classification of pulmonary nodules.
Published 2025-01-01“…The benign and malignant discrimination of pulmonary nodules plays a very important role in diagnosing the extent of lung cancer lesions. There are many methods using Convolutional neural network (CNN) for benign and malignant classification of pulmonary nodules, but traditional CNN models focus more on the local features of pulmonary nodules and lack the extraction of global features of pulmonary nodules. …”
Get full text
Article -
84
HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses.
Published 2025-02-01“…Additionally, they suggest that many lung cancer-related genes may exert their roles in immune cells. …”
Get full text
Article -
85
Design and Analysis of thermosyphon Solar Water Heating System.
Published 2024“…In rural areas of Uganda, access to affordable hot water is a persistent challenge with communities often relying on firewood and charcoal for water heating which contributes to deforestation, air pollution, and health hazards hence respiratory diseases like asthma, lung cancer, TB, and allergic disease, climate changes and global warming. …”
Get full text
Thesis -
86
Colony-Forming and Cell Viability Assay to Assess Nanotoxicity of Maleic Acid and N-vinyl Caprolactam-Based Nanoarchitectures
Published 2025-01-01“…The cytotoxicity of Org-MMT, poly(MA-alt-VCL), and their nanocomposites were tested on HeLa (cervical carcinoma), A549 (lung cancer), and HDF (human dermal fibroblast) cells using MTT and colony formation assays. …”
Get full text
Article -
87
The 500-year Cultural & Economic Trajectory of Tobacco: A Circle Complete
Published 2017-12-01“…Solid epidemiological work connecting tobacco use with “the shortening of life span” began to appear in the medical literature in the 1950s, linking smoking with lung cancer and related conditions. In subsequent years, these developments led to significant curtailment of tobacco use. …”
Get full text
Article -
88
The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes
Published 2025-02-01“…Research shows that abnormal expression of ESRP1 is closely related to the formation and development of various solid tumors, including breast cancer, lung cancer, stomach cancer, and others, and is closely associated with the invasiveness, metastasis, and poor prognosis of tumors. …”
Get full text
Article -
89
Machine learning identifies the association between second primary malignancies and postoperative radiotherapy in young-onset breast cancer patients.
Published 2025-01-01“…YWBC patients receiving PORT had significantly greater risks of second primary solid malignancies (SPSMs, RR = 1.61), including breast cancer (RR = 1.89), lung cancer (RR = 2.12) and thyroid cancer (RR = 1.48), but not second primary hematologic malignancies (RR = 1.32; 0.94-1.88). …”
Get full text
Article -
90
Screening of multi deep learning-based de novo molecular generation models and their application for specific target molecular generation
Published 2025-02-01“…Moreover, we evaluated the performance of these NLP-based generation models and another new model architecture based on a selective state space and selected the best approach jointing a transfer learning strategy for de novo drug discovery to target L858R/T790M/C797S-mutant EGFR in non-small cell lung cancer.…”
Get full text
Article -
91
Quantum computational infusion in extreme learning machines for early multi-cancer detection
Published 2025-02-01“…Results demonstrate that Q-GBGWO-ELM improves diagnostic accuracy by an average of 6.5% compared to traditional methods, with notable accuracy rates across various cancers: 98.80% for breast cancer, 92.30% for brain tumors, 97.00% for skin cancer, and 96.98% for lung cancer. The model integrates advanced feature extraction and optimization techniques, indicating significant potential for early cancer detection. …”
Get full text
Article -
92
Clinical benefits of the 5th intercostal incision in uniportal VATS for female patients
Published 2025-02-01“…A retrospective analysis of 150 female lung cancer patients was conducted, divided into 4 and 5th intercostal incision groups (n = 75 each). …”
Get full text
Article -
93
A cross-sectional survey on the effects of ambient temperature and humidity on health outcomes in individuals with chronic respiratory disease
Published 2023-12-01“…., asthma, sleep apnea, interstitial lung disease, lung cancer) and residing in Canada for ≥ 1 year. Negative responders to weather extremes were *a priori* defined as having a change of ≥ 2 points in the CAT…”
Get full text
Article -
94
Unraveling relationship between the genetic polymorphism CYP2A13 and nicotine metabolism of male smokers in Medan, Indonesia
Published 2025-02-01“…CYP2A13, a key enzyme in nicotine and xenobiotic metabolism, is implicated in tobacco smoke-related lung cancer. Aim This study investigated the association between CYP2A13 genetic polymorphism and nicotine metabolism in male smokers in Medan, Indonesia. …”
Get full text
Article -
95
The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study
Published 2025-02-01“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. …”
Get full text
Article -
96
Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases
Published 2025-02-01“…Luteolin has therapeutic effects on chronic obstructive pulmonary disease (COPD), acute lung injury/acute respiratory distress syndrome (ALI/ARDS), pulmonary fibrosis, allergic asthma, and lung cancer. Luteolin, a naturally occurring polyphenol, is poorly water-soluble. …”
Get full text
Article -
97
A novel hybrid CLARA and fuzzy time series Markov chain model for predicting air pollution in Jakarta
Published 2025-06-01“…Poor air quality increases risks of respiratory inflammation, tuberculosis, asthma, chronic obstructive pulmonary disease (COPD), pneumoconiosis, and lung cancer.In this context, developing reliable air pollution forecasting models is imperative for guiding effective mitigation strategies and policy interventions. …”
Get full text
Article -
98
Comparative analysis of alectinib and brigatinib in real-world treatment of advanced NSCLC with ALK rearrangements
Published 2025-02-01“…Background and objectives: This study aimed to compare the efficacy of the second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) alectinib and brigatinib in the treatment of advanced non-small-cell lung cancer (NSCLC) with ALK rearrangements based on real-world data. …”
Get full text
Article -
99
Solitary metastasis in the internal auditory canal from non-small cell lung carcinoma: A case report
Published 2025-01-01“…Discussion: IAC metastases are rare, representing only 0.3%–0.7 % of all lesions in this anatomical space. Lung cancer is a common primary source. Clinically, IAC metastases manifest with acute onset and rapid symptom progression, often mimicking benign conditions. …”
Get full text
Article -
100
Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development
Published 2024-04-01“…We previously characterized the lung cancer microbiome in patients and identified Acidovorax temperans as enriched in tumors. …”
Get full text
Article