Showing 1 - 20 results of 31 for search '"liver cancer"', query time: 0.10s Refine Results
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    Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC by Anqi Wang, Sitong Yan, Jiatao Liu, Xiang Chen, Mengyao Hu, Xiao Du, Weijia Jiang, Zhipeng Pan, Lulu Fan, Guoping Sun

    Published 2025-02-01
    “…Mechanistically, CREB5 upregulates the transcription of tenascin-C (TNC) by directly binding to its promoter region, thereby promoting EMT in liver cancer cells. In summary, our findings suggest that ERS activation promotes EMT in liver cancer cells via SE-mediated upregulation of the CREB5/TNC pathway. …”
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    Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

    Published 2025-02-01
    “…Abstract Liver cancer represents a major global health concern, with projections indicating that the number of new cases could surpass 1 million annually by 2025. …”
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    To construct and validate a risk score model of angiogenesis-related genes to predict the prognosis of hepatocellular carcinoma by Duangui Gao, Yuan Lu, Tianpeng Jiang, Qinghong Duan, Zhi Huang

    Published 2025-02-01
    “…On the single-cell level, it was confirmed that the key genes (AEBP1, ATP2A3, PLAT, and PNMA1) expressed differently between liver cancer and adjacent tissue cell groups. Finally, qRT_PCR and WB results showed that ATP2A3, AEBP1, PNMA1, and PLAT were highly expressed in liver cancer tissue compared to adjacent tissue, and the proliferation, migration, and invasion of HCCLM3 cells were inhibited after knocking out AEBP1. …”
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    Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma. by Md Al Mehedi Hasan, Md Maniruzzaman, Jie Huang, Jungpil Shin

    Published 2025-01-01
    “…Hepatocellular carcinoma (HCC) is the most prevalent and deadly form of liver cancer, and its mortality rate is gradually increasing worldwide. …”
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    Role of alpha-fetoprotein in complex diagnostics of progressing course of chronic hepatitis B and C by I. A. Belavina, O. P. Dudanova

    Published 2012-06-01
    “…Overall 69 patients with chronic viral hepatitis were investigated: 39 with chronic hepatitis B (CHB) and 30 — with chronic hepatitis C (CHC) without signs of cirrhotic transformation and liver cancer. The diagnosis was verified by clinical, laboratory and morphological – with assessment of histological activity index (HAI) and histological sclerosis index (HSI), instrumental (transabdominal ultrasound, Doppler ultrasonography of portal blood flow), virologic studies. …”
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    Helicobacter pylori Infection and Hepatobiliary Pathology by S. V. German, I. P. Bobrovnitsky

    Published 2018-09-01
    “…Different species of the Helicobacter genus, including H. pylori, are shown to contribute to the development of liver cancer. However, some researchers report data against the involvement of H. pylori in the pathogenesis of various hepatobiliary diseases.Conclusion.  …”
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