Unraveling multimodality of digital health records by comparing mortality trajectories of diagnoses of diseases from over 12 million patients. by Hyojung Paik

“…For example, viral hepatitis, a known predisposing feature of liver cancer in Asia, was observed to initiate in younger Koreans. …”
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An Overview of In Vitro Models of Alcohol‐Related Hepatocellular Carcinoma by Anoïsia Courtois, Sophie Gérard, Damien Esparteiro, Eric Nguyen‐Khac, Ingrid Marcq, Grégory Fouquet

“…Alcohol‐related liver disease (ALD) encompasses a broad spectrum of clinical and pathological features, ranging from asymptomatic and reversible pathologies to hepatocellular carcinoma (HCC), a highly prevalent and deadly liver cancer. Indeed, alcohol consumption is one of the main worldwide etiologies of HCC. …”
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The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background by Jinsheng Yu, Sharon Marsh, Junbo Hu, Wenke Feng, Chaodong Wu

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to steatohepatitis, fibrosis, cirrhosis, and liver cancer. While the pathogenesis of NAFLD remains incompletely understood, a multihit model has been proposed that accommodates causal factors from a variety of sources, including intestinal and adipose proinflammatory stimuli acting on the liver simultaneously. …”
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Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats by Salah M. Aly, Hamdy A. Fetaih, Abeer A. I. Hassanin, Mosleh M. Abomughaid, Aliaa A. Ismail

“…The HCC-induced group showed histopathological features of liver cancer including hypercellularity, nuclear hyperchromasia, mitotic figures, and preneoplastic foci. …”
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High order expression dependencies finely resolve cryptic states and subtypes in single cell data by Abel Jansma, Yuelin Yao, Jareth Wolfe, Luigi Del Debbio, Sjoerd V Beentjes, Chris P Ponting, Ava Khamseh

“…Further, Stator’s fine resolution of liver cancer states reveals expression programmes that predict patient survival. …”
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Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

“…Xuejuan Wang, Li Li, Yun Wang Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Yun Wang, Department of anesthesiology, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong’an Road, Xicheng District, Beijing, 100050, People’s Republic of China, Email wangyun129@ccmu.edu.cnAbstract: Bone is a common site of advanced cancer metastasis, second only to the lungs and liver. Cancer-induced bone pain (CIBP) is a persistent and intense pain that is caused by a combination of inflammatory and neuropathic factors. …”
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Rural-Urban Disparity in Premature Cancer Mortality in Young People Aged 15–44 Years in China, 2004–2021 by Chunrong Chen, Xing Xing, Shaojie Li, Bo Qu, Chunyu Liu, He Zhu, He Zhu

“…More efforts are needed to develop effective early-onset cancer prevention strategies, with particular emphasis on liver cancer and rural areas.…”
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Feasibility and Efficacy of S-Adenosyl-L-methionine in Patients with HBV-Related HCC with Different BCLC Stages by Tao Guo, Yukun He, Weijie Ma, Zhisu Liu, Quanyan Liu

“…To understand the feasibility and efficacy of treatment with SAMe in patients with hepatitis B-related HCC with different Barcelona Clinic Liver Cancer (BCLC) stages. Methods. We retrospectively enrolled 697 patients with BCLC early-stage (stages 0-A) and advanced-stage (stages B-C) HCC who underwent SAMe therapy (354 cases) or no SAMe therapy (343 cases). …”
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The Use of Noninvasive Velacur® for Discriminating between Volunteers and Patients with Chronic Liver Disease: A Feasibility Study by Michael P. Curry, Edward Tam, Caitlin Schneider, Noha Abdelgelil, Tarek Hassanien, Nezam H. Afdhal

“…Nonalcoholic fatty liver disease is the leading cause of chronic liver disease globally and can progress to cirrhosis, liver failure, and liver cancer. Current AASLD, AGA, and ADA guidelines recommend assessment for liver fibrosis in all patients with NAFLD. …”
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Factors Affecting the Survival of Patients with Oligometastatic Non-Small-Cell Lung Cancer: A Meta-Analysis by Yu Shi, Jianxin Yang, Ninghua Yao, Minghai Shao, Wenxiu Ding, Wanrong Jiang, Xinchen Sun

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Spatial Distribution and Dietary Risk Assessment of Aflatoxins in Raw Milk and Dairy Feedstuff Samples from Different Climate Zones in China by Xueli Yang, Bolin Liu, Lei Zhang, Xiaodan Wang, Jian Xie, Jiang Liang

“…On average, the estimated dietary exposure to AFM1 from milk and dairy products for Chinese consumers ranged from 0.0138 to 0.0281 ng/kg bw/day, with the MOE values below 10,000, and liver cancer risk of 0.00004–0.00009 cases/100,000 persons/year. …”
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Evaluation of the Selenotranscriptome Expression in Two Hepatocellular Carcinoma Cell Lines by Stefano Guariniello, Giovanni Di Bernardo, Giovanni Colonna, Marcella Cammarota, Giuseppe Castello, Susan Costantini

“…Hepatocellular carcinoma (HCC) is the most common type of liver cancer and is still one of the most fatal cancers. …”
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SiameseNet based on multiple instance learning for accurate identification of the histological grade of ICC tumors by Zhizhan Fu, Fazhi Feng, Xingguang He, Tongtong Li, Xiansong Li, Jituome Ziluo, Zixing Huang, Jinlin Ye

“…BackgroundAfter hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer. Timely and accurate identification of ICC histological grade is critical for guiding clinical diagnosis and treatment planning.MethodWe proposed a dual-branch deep neural network (SiameseNet) based on multiple-instance learning and cross-attention mechanisms to address tumor heterogeneity in ICC histological grade prediction. …”
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Design, Synthesis and Pharmacological Screening of β-Amino-, Thiadiazole/Thiadiazine-Phosphonate Based Triazole Motifs as Antimicrobial/Cytotoxic Agents by Abdou Wafaa M., Ganoub Neven A., Sabry Eman

“…The results showed that all synthesized compounds reflected remarkable antitumor activity against breast (especially MDA-MB-231/ATCC and BT-549), and prostate carcinoma cell lines (PC-3 and DU-145), whereas a moderate to good effect on ovarian and liver cancer cells was observed.…”
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ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition by Si-qi Zhao, Min-jie Chen, Fei Chen, Zhao-feng Gao, Xiao-ping Li, Ling-yu Hu, Hai-ying Cheng, Jin-yan Xuan, Jian-guo Fei, Zheng-wei Song

“…Immunohistochemistry, The Cancer Genome Atlas (TCGA) data, and single-cell expression analysis revealed reduced ENTPD8 levels in liver cancer compared to adjacent tissues, with ENTPD8 primarily expressed in tumor cells within the tumor tissue. …”
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Comprehensive Analysis on the Specific Role and Function of Mitochondrial Inner Membrane Protein MPV17 in Liver Hepatocellular Carcinoma by Hanchuan Tao, Cheng Wang, Chongmei Lu, Ning Ma, Yifan Zhu, Shihai Xuan, Xiaojun Zhou

“…Liver hepatocellular carcinoma (LIHC) is the predominant type of liver cancer, and its treatment still faces great challenges presently. …”
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Transcatheter Arterial Chemoembolization Based on Hepatic Hemodynamics for Hepatocellular Carcinoma by Satoru Murata, Takahiko Mine, Tatsuo Ueda, Ken Nakazawa, Shiro Onozawa, Daisuke Yasui, Shin-ichiro Kumita

“…The Barcelona Clinic Liver Cancer (BCLC) classification has recently emerged as the standard classification system for clinical management of patients with HCC. …”
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Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase by Thomas Große-Steffen, Thomas Giese, Nathalia Giese, Thomas Longerich, Peter Schirmacher, G. Maria Hänsch, Matthias M. Gaida

“…PMN as well as prevention of adhesion induced EMT also in liver cancer cell line. In conclusion, PMN via elastase induce EMT in vitro, most likely due to the loss of cell-to-cell contact. …”
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TGF-β signaling orchestrates cancer-associated fibroblasts in the tumor microenvironment of human hepatocellular carcinoma: unveiling insights and clinical significance by Junwei Ge, Hongwei Jiang, Junjun Chen, Xuemin Chen, Yue Zhang, Liangrong Shi, Xiao Zheng, Jingting Jiang, Lujun Chen

“…Abstract Liver cancer, specifically hepatocellular carcinoma (HCC), stands out as one of the most formidable solid tumors, characterized by a dauntingly low survival rate. …”
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Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma by Kawuli Jumai, Tangjuan Zhang, Bingzhang Qiao, Julaiti Ainiwaer, Haiping Zhang, Zhichao Hou, Idris Awut, Madinyat Niyaz, Liwei Zhang, Ilyar Sheyhidin

“…Experiments in the literature on liver cancer (LC) were repeated to verify the functions of these genes in different tumors. …”
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