Preoperative Thrombocytopenia May Predict Poor Surgical Outcome after Extended Hepatectomy by Mohammad Golriz, Omid Ghamarnejad, Elias Khajeh, Mohammadsadegh Sabagh, Markus Mieth, Katrin Hoffmann, Alexis Ulrich, Thilo Hackert, Karl Heinz Weiss, Peter Schirmacher, Markus W. Büchler, Arianeb Mehrabi

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The XIAP inhibitor AZD5582 improves the treatment effect of microwave ablation on hepatocellular carcinoma by Wenhui Wang, Fuyuan Wu, Zhe Wu, Mengfan Zhang, Qiang Lu

“…However, the residual tumor, resulting from insufficient ablation, led to recurrence and metastasis of liver cancer. Novel combination strategies are urgently needed to enhance efficiency of MWA.MethodsWe detected the expression of XIAP protein after ablation in primary liver cancer patients using immunohistochemistry. …”
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Nomogram to Predict the Survival of Chinese Patients with Alcohol-Related Liver Disease by Fangfang Duan, Chen Liu, Yuwei Liu, Chunyan Chang, Hang Zhai, Huichun Xing, Jun Cheng, Song Yang

“…Relapse, cirrhosis, liver cancer, and a model for end-stage liver disease score of ≥21 were independent risk factors for those patients. …”
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A Meta-Analysis of Statin Use and Risk of Hepatocellular Carcinoma by Yikai Wang, Wenjun Wang, Muqi Wang, Juanjuan Shi, Xiaoli Jia, Shuangsuo Dang

“…Our meta-analysis shows that the use of statins is associated with a lower risk of liver cancer.…”
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Multi-scale channel attention U-Net: a novel framework for automated gallbladder segmentation in medical imaging by Yiming Zhou, Xiaobo Wen, Xiaobo Wen, Kang Fu, Meina Li, Lin Sun, Xiao Hu

“…ObjectivesTo develop a novel automatic delineation model, the Multi-Scale Channel Attention U-Net (MCAU-Net) model, for gallbladder segmentation on CT images of patients with liver cancer.MethodsWe retrospectively collected the CT images from 120 patients with liver cancer, based on which ground truth was manually delineated by physicians. …”
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Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

“…Abstract Liver cancer represents a major global health concern, with projections indicating that the number of new cases could surpass 1 million annually by 2025. …”
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Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis... by P. S. Demenkov, E. A. Antropova, A. V. Adamovskaya, E. I. Mishchenko, T. M. Khlebodarova, T. V. Ivanisenko, N. V. Ivanisenko, A. S. Venzel, I. N. Lavrik, V. A. Ivanisenko

“…Hepatocellular carcinoma (HCC) is a common severe type of liver cancer characterized by an extremely aggressive course and low survival rates. …”
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Advance of Mesenchymal Stem Cells in Chronic End-Stage Liver Disease Control by Yun Gao, Xiushan Yin, Xiaomeng Ren

“…The chronic liver diseases will slowly develop into liver fibrosis, cirrhosis, and even liver cancer if no proper control is performed with high efficiency. …”
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Olfm4 Is Highly Expressed in HCC Patients and as a Biomarker and Therapeutic Target for HCC by Yulong Wei, Qingzhu Song, Fenglan Zhang, Tian Yuan

“…Conventional therapies against liver cancer are inadequate, and the pathogenesis of HCC remains unclear. …”
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Clinical Application of Partial Splenic Embolization by Yong-Song Guan, Ying Hu

“…Common indications of PSE include hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia, autoimmune hemolytic anemia, splenic trauma, idiopathic thrombocytopenic purpura, splenic hemangioma, and liver cancer. It is also performed to exclude splenic artery aneurysms from the parent vessel lumen and prevent aneurysm rupture, to treat splenic artery steal syndrome and improve liver perfusion in liver transplant recipients, and to administer targeted treatment to areas of neoplastic disease in the splenic parenchyma. …”
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To construct and validate a risk score model of angiogenesis-related genes to predict the prognosis of hepatocellular carcinoma by Duangui Gao, Yuan Lu, Tianpeng Jiang, Qinghong Duan, Zhi Huang

“…On the single-cell level, it was confirmed that the key genes (AEBP1, ATP2A3, PLAT, and PNMA1) expressed differently between liver cancer and adjacent tissue cell groups. Finally, qRT_PCR and WB results showed that ATP2A3, AEBP1, PNMA1, and PLAT were highly expressed in liver cancer tissue compared to adjacent tissue, and the proliferation, migration, and invasion of HCCLM3 cells were inhibited after knocking out AEBP1. …”
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Circulating Tumor Cells Measurements in Hepatocellular Carcinoma by Franck Chiappini

“…Liver cancer is the fifth most common cancer in men and the seventh in women. …”
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LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis. by Lin Zhu, Qianqian Meng, Weiyi Qian, Weiting Shao, Yuyue Lu, Shuai Jin, Afei Zhang, Shuang G Yan, Jingtao Lu

“…We found that it is significantly highly expressed in the liver cancer tissues of HCC patients, but the exact role and specific mechanism of this abnormal expression are not yet clear. …”
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Fibrolamellar Carcinoma: 2012 Update by Michael Torbenson

“…Fibrolamellar carcinomas are a unique type of primary liver cancer. They occur most commonly in children and young adults. …”
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A Rare Case of Metastatic Hepatocellular Carcinoma Masquerading as a Forehead Hematoma by Kimberly Sanders, Ashley Thomas, Carmen Isache, Anwer Siddiqi

“…Hepatocellular carcinoma (HCC) is the most common primary liver cancer and can arise from any form of chronic liver disease or cirrhosis. …”
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Nanomaterials based biosensors applied for detection of aflatoxin B1 in cereals: a review by Loyce Namanya, Emma Panzi Mukhokosi, Ediriisa Mugampoza

“…Liver damage is a result of prolonged exposure to AFB1, which raises the prevalence of liver cancer and cirrhosis. Different biosensors have been fabricated using various nanoparticles to detect aflatoxins in food. …”
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Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases by Ting Liu, Yu Zhou, Kwang Suk Ko, Heping Yang

“…Their interactions play a central role in fibrosis, cirrhosis, and liver cancer. Molecular interference of their interactions offers possible therapeutic potential for CLDs. …”
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Structural insights into antibody-based immunotherapy for hepatocellular carcinoma by Masaud Shah, Muhammad Hussain, Hyun Goo Woo

“…Abstract Hepatocellular carcinoma (HCC) is one of the most common types of primary liver cancer and remains a leading cause of cancer-related deaths worldwide. …”
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Occurrence of Alternaria Toxins, Ochratoxin A and Aflatoxins B1 in Green Arabic Coffee (Coffea arabica) in Saudi Arabia: Risk Assessment on HepG-2 Cell Line and Male Albino Rats by Ahmed Hashim Almusallam, Ahmed Mahmoud Ismail

“…The current study aimed to detect and quantify of potential mycotoxins in coffee beans and to investigate their potential risk on HepG-2 human liver cancer cells and male albino rats. Eighteen fully matured coffee beans samples were collected from different geographical locations in Saudi Arabia. …”
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Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide by Abdou Saad El-Tabl, Moshira Mohamed Abd El-Waheed, Mohammed Ahmed Wahba, Nahla Abd El-Halim Abou El-Fadl

“…The cytotoxic activity of the ligand and its metal complexes showed potent cytotoxicity effect against growth of human liver cancer HepG2 cell lines compared to the clinically used Sorafenib (Nexavar).…”
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